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Externally applied traditional Chinese medicine composition for treating rheumatic arthritis and preparation method thereof

A technology of rheumatoid arthritis and composition, which is applied in the field of externally applied traditional Chinese medicine composition and its preparation for the treatment of rheumatoid arthritis. Transforming performance, improving blood circulation, and accelerating blood flow

Pending Publication Date: 2020-10-09
苏州康富多生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Nowadays, it is generally relieved by anti-inflammatory and analgesic drugs during treatment, but because most of the western medicines have strong side effects, long-term use will damage human health, and at the same time, the drug dependence is strong and the disease cannot be cured. Therefore, the invention discloses a treatment for rheumatism. Externally applied traditional Chinese medicine composition for rheumatoid arthritis and preparation method thereof, fundamentally treat rheumatoid arthritis, to solve this problem

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] S1: Preparation of external dressing:

[0061] Take graphene oxide and absolute ethanol, mix and stir for 5 minutes, sonicate for 1 hour, then add triaminopropyltriethoxysilane, reflux reaction at 70°C water bath temperature for 4 hours, centrifuge, take the solid phase and wash it, at 90°C vacuum drying to obtain modified graphene oxide;

[0062] Take polyacrylic acid aqueous solution and ammonia water, ultrasonically treat for 10 minutes, then slowly add isopropanol dropwise, and continue to stir during the dropwise addition to obtain material A; take material A, continue to add isopropanol, chloroauric acid trihydrate, Stirring and reacting for 2 hours, then adding ascorbic acid, reacting for 1 hour, centrifuging, washing, and drying to obtain a hollow carrier;

[0063] Take notopterygium, lovage and Scorpion grass, soak in 85% ethanol for 30 minutes, ultrasonically extract at 60°C for 30 minutes, cool, filter to obtain the primary filtrate, repeat the methanol extr...

Embodiment 2

[0073] S1: Preparation of external dressing:

[0074] Take graphene oxide and absolute ethanol, mix and stir for 8 minutes, sonicate for 1.1 hours, then add triaminopropyltriethoxysilane, reflux for 4.2 hours at 72°C water bath temperature, centrifuge, take the solid phase and wash, 95 Vacuum drying at ℃ to obtain modified graphene oxide;

[0075] Take polyacrylic acid aqueous solution and ammonia water, ultrasonically treat for 12 minutes, then slowly add isopropanol dropwise, and continue to stir during the dropwise addition process to obtain material A; take material A, continue to add isopropanol, chloroauric acid trihydrate, Stir and react for 2.3 hours, then add ascorbic acid, react for 1.1 hours, centrifuge, wash, and dry to obtain a hollow carrier;

[0076] Take notopterygium, lovage and Scorpion grass, soak in 85% ethanol for 35 minutes, ultrasonically extract at 62°C for 35 minutes, cool, filter to obtain the primary filtrate, repeat the methanol extraction step on ...

Embodiment 3

[0086] S1: Preparation of external dressing:

[0087] Take graphene oxide and absolute ethanol, mix and stir for 10 minutes, sonicate for 1.2 hours, then add triaminopropyltriethoxysilane, reflux reaction at 75°C water bath temperature for 4.5 hours, centrifuge, take the solid phase and wash it, 100 Vacuum drying at ℃ to obtain modified graphene oxide;

[0088] Take polyacrylic acid aqueous solution and ammonia water, ultrasonically treat for 15 minutes, then slowly add isopropanol dropwise, and continue to stir during the dropwise addition process to obtain material A; take material A, continue to add isopropanol and chloroauric acid trihydrate, at 28°C Stir and react for 2.5 hours, then add ascorbic acid, react for 1.2 hours, centrifuge, wash, and dry to obtain a hollow carrier;

[0089] Take notopterygium, lovage and scorpion grass, soak in 85% ethanol for 40 minutes, ultrasonically extract at 65°C for 40 minutes, cool, filter to obtain the primary filtrate, repeat the met...

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PUM

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Abstract

The invention discloses an externally applied traditional Chinese medicine composition for treating rheumatic arthritis and a preparation method thereof, the externally applied traditional Chinese medicine composition comprises at least two layers of base cloth and an external dressing, a layer of heat conduction material is laid between every two adjacent layers of base cloth, and the external dressing is coated on the surface of the uppermost layer of base cloth; and the external dressing is prepared from notopterygium root, radix angelicae pubescentis, scorpion grass, large-leaved gentian,radix clematidis, caulis spatholobi, cassia twig, peach kernel, bighead atractylodes rhizome, radix paeoniae rubra, angelica sinensis and the like. The traditional Chinese medicine composition is reasonable in process design and proper in component proportion, the prepared traditional Chinese medicine composition needs to be used by assisting infrared rays, heat can be generated through the infrared rays in the using process, and therefore hot compress is conducted on joints, and arthralgia is relieved while the effect of the external dressing is improved; the external dressing combines the functions of clearing heat, dispersing blood stasis, resolving dampness, dispelling wind, promoting blood circulation and tonifying kidney, and can be used for effectively treating rheumatism or rheumatoid arthritis and other diseases.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to an externally applied traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis is a common acute or chronic inflammation of connective tissue. Commonly said rheumatoid arthritis is one of the main manifestations of rheumatic fever, clinically characterized by joint and muscle migratory soreness, redness and pain. It is related to group A beta-hemolytic streptococcal infection, and factors such as cold and humidity can induce the disease. Although the incidence of rheumatic fever has decreased significantly in recent decades, atypical rheumatic fever and chronic rheumatic arthritis are not uncommon. [0003] Nowadays, it is generally relieved by anti-inflammatory and analgesic drugs during treatment, but because most of the western medicines have strong si...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K41/00A61K36/8984A61K9/70A61K47/02A61K47/32A61N5/06A61F7/02A61P19/02A61P29/00
CPCA61K36/237A61K36/232A61K36/185A61K36/515A61K36/716A61K36/486A61K36/54A61K36/736A61K36/284A61K36/71A61K36/65A61K36/8984A61K36/746A61K36/258A61K36/126A61K9/7023A61K47/02A61K47/32A61K41/0052A61P19/02A61P29/00A61N5/0625A61F7/02A61N2005/0643A61N2005/0659A61F2007/0088A61F2007/0261A61F2007/0203A61K2300/00
Inventor 吴学峰
Owner 苏州康富多生物科技有限公司
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