Preparation method of radix polygoni multiflori and ginseng bowel relaxing preparation

A Shouhui laxative and preparation technology, which is applied in the field of preparation of Shouhui laxative preparations, can solve the problems of large loss, loss of medicinal ingredients, waste of medicinal material resources, etc., and achieve the improvement of dry matter quality, clinical curative effect, and high-efficiency enrichment The effect of using

Inactive Publication Date: 2020-08-25
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The medicinal ingredients of Lycium barbarum and Atractylodes macrocephala are mainly polysaccharides and amino acids. The water extraction and alcohol precipitation process will cause a great loss of medicinal polysaccharides and amino acids, resulting in the loss of the medicinal ingredients of Shouhui laxative preparation.
Although the clinical curative effect of Shouhui Laxative Capsules is definite at present, the existing preparation process also causes a waste of medicinal material resources, so it is necessary to optimize and upgrade the preparation method of the existing Shouhui Laxative preparations so that it can make full use of raw materials Herb resources can achieve higher quality and better clinical efficacy, and can also simplify operations and save labor costs

Method used

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  • Preparation method of radix polygoni multiflori and ginseng bowel relaxing preparation
  • Preparation method of radix polygoni multiflori and ginseng bowel relaxing preparation
  • Preparation method of radix polygoni multiflori and ginseng bowel relaxing preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0143] The preparation of embodiment 1 Shouhui laxative granule

[0144] He Shou Wu 150g Aloe Vera 200g Cassia Seed 180g

[0145] Ginseng 20g Wolfberry 30g Donkey-hide gelatin 30g

[0146] Citrus aurantium 150g Atractylodes macrocephala 80g

[0147] A. Take Radix Polygoni Multiflori, Aloe Vera, Semen Cassiae, Ginseng, Fructus Lycium Barbarum, Ejiao, Fructus Aurantii, Atractylodes Atractylodes Eight Flavors, and grind Ejiao to obtain fine powder of Ejiao, which is set aside; ginseng is reflux extracted twice with 9 times the amount of 45% ethanol, each time 1 hours, the reflux liquid was concentrated under reduced pressure to an extract with a relative density of 1.17 at 70°C-80°C to obtain extract I and ginseng dregs for subsequent use;

[0148] B. Ginseng dregs, Lycium barbarum fruit, Atractylodes citrus aurantium and Atractylodes macrocephala, add 8 times the amount of water to decoct and extract twice, each time for 1 hour, the decoction solution is centrifuged at 10000r / ...

Embodiment 2

[0151] The preparation of embodiment 2 Shouhui catharsis tablet

[0152] Polygonum multiflorum 100g Aloe vera 150g Cassia seed 130g

[0153] Ginseng 50g Wolfberry 30g Donkey-hide gelatin 70g

[0154] Citrus aurantium 115g Atractylodes macrocephala 45g

[0155] A. Take Radix Polygoni Multiflori, Aloe Vera, Semen Cassiae, Ginseng, Fructus Lycium Barbarum, Ejiao, Fructus Aurantii, Atractylodes Atractylodes Bawei, and Ejiao is crushed to obtain fine powder of Ejiao, which is set aside; Ginseng is extracted twice with 10 times the amount of 50% ethanol, each time 1 Hours, the reflux liquid was concentrated under reduced pressure to an extract with a relative density of 1.10 at 70°C-80°C to obtain extract I and ginseng dregs for subsequent use;

[0156] B. Ginseng dregs, Lycium barbarum fruit, Citrus aurantii, Atractylodes macrocephala plus 10 times the amount of water are decocted and extracted twice, each time for 2 hours, the decoction solution is centrifuged at 9000r / min, filt...

Embodiment 3

[0159] The preparation of embodiment 3 Shouhui laxative granules

[0160] Polygonum multiflorum 70g Aloe vera 120g Cassia seed 100g

[0161] Ginseng 70g Wolfberry 90g Donkey-hide gelatin 80g

[0162] Citrus aurantium 110g Atractylodes macrocephala 40g

[0163] A. Take Radix Polygoni Multiflori, Aloe Vera, Semen Cassiae, Ginseng, Fructus Lycium Barbarum, Ejiao, Fructus Aurantii, Atractylodes Atractylodes Eight Flavors, and grind Ejiao to obtain fine powder of Ejiao, which is set aside; ginseng is extracted twice with 8 times the amount of 40% ethanol, each time 1 hours, the reflux liquid was concentrated under reduced pressure to an extract with a relative density of 1.15 at 70°C-80°C to obtain extract I and ginseng dregs for subsequent use;

[0164] B. Ginseng dregs, Lycium barbarum fruit, Citrus aurantium, Atractylodes macrocephala plus 9 times the amount of water are decocted and extracted twice, each time for 0.5 hours, the decoction liquid is centrifuged at 8500r / min, fi...

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Abstract

The invention belongs to the field of traditional Chinese medicine preparations, and discloses a novel preparation method of a radix polygoni multiflori and ginseng bowel relaxing preparation. Compared with an original preparation process, the preparation process disclosed by the invention improves the contents of ginsenoside Rg1, ginsenoside Re, stibene glucoside, naringin and synephrine in the radix polygoni multiflori and ginseng bowel relaxing preparation, so that polysaccharide components in radix ginseng, fructus lycii and rhizoma atractylodis macrocephalae are efficiently enriched and utilized, and the dry matter quality of an extract is also remarkably improved. The preparation process of the radix polygoni multiflori and ginseng bowel relaxing preparation, disclosed by the invention, can save medicinal material resources and the cost of artificial materials; the obtained radix polygoni multiflori and ginseng bowel relaxing preparation is high in content of medicinal components, and the clinical curative effect of a product is improved.

Description

technical field [0001] The invention relates to a preparation method of Shouhui laxative preparation, which belongs to the field of traditional Chinese medicine preparations. Background technique [0002] Functional constipation is caused by conduction failure in the large intestine. Various symptoms such as abdominal pain and nervousness. Epidemiological surveys show that the incidence of constipation in my country is 3.0% to 17.0%. The incidence of functional constipation is generally higher in the elderly than in the young, and in women than in men. Constipation can not only cause anal diseases such as hemorrhoids and fissures, but also induce and aggravate various cardiovascular and cerebrovascular diseases, increase the risk of colon cancer, and make patients in a state of anxiety, depression and other emotional abnormalities for a long time. Functional constipation is a common clinical disease and one of the refractory diseases in the world. With the aging of the po...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/886A61P1/10A61K35/36
CPCA61K35/36A61K36/258A61K36/284A61K36/482A61K36/704A61K36/752A61K36/815A61K36/886A61K36/896A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61P1/10A61K2300/00
Inventor 张贵民王永刚冯倩张翠云
Owner LUNAN PHARMA GROUP CORPORATION
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