Multifunctional medical mouthwash and preparation method thereof

A mouthwash, multi-functional technology, applied in the field of mouthwash, can solve the problem of single function of mouthwash, and achieve the effects of relieving oral pain and discomfort, fast drug effect and increasing applicability

Inactive Publication Date: 2020-08-07
卓颖
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of the above problems, the present invention provides a multifunctional medical mouthwash and preparation method thereof, in order to solve the problem that the function of the current mouthwash is too single

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A multifunctional medical mouthwash (hereinafter referred to as "mouthwash"), the mouthwash at least includes nimesulide and sodium fluoride, and the rest is distilled water. Nimesulide is a non-steroidal anti-inflammatory drug, which can be used clinically for the treatment of pain after surgery and acute trauma, and the symptoms of primary dysmenorrhea. The invention applies nimesulide to one of the components of mouthwash before and after oral surgery, which can effectively reduce the pain of patients before and after oral surgery. Adding sodium fluoride to mouthwash can prevent caries, because it is difficult for patients to brush their teeth normally after oral surgery, which increases the risk of dental caries in the perioperative period, and the interaction between sodium fluoride and enamel can form on the surface of enamel Fluorapatite can improve the hardness and acid resistance of tooth enamel, and can reduce the formation of plaque and reduce the incidence o...

Embodiment 2

[0023] An embodiment of the mouthwash of the present invention, the weight percent of nimesulide in the mouthwash is 0.01-1%, the weight percent of sodium fluoride in the mouthwash is 0.02-0.5%, and the weight percent of lidocaine in the mouthwash 0.5-5%, the weight percentage of ethanol in the mouthwash is 10-20%, and the weight percentage of sorbitol in the mouthwash is 10-20%. Among them, low-dose lidocaine can act as local anesthesia, has fast drug effect, does not have any irritation to oral cells and tissues, and can relieve oral pain of patients.

[0024] The preparation method of the mouthwash that present embodiment proposes is:

[0025] According to the above-mentioned proportions by weight, after fully mixing the proportions of the mouthwash components (the mouthwash components include at least nimesulide, sodium fluoride, lidocaine, ethanol and sorbitol) by stirring the magnet to mix uniformly in the time range of 0.5 Within ~2 hours, gradually add distilled water...

Embodiment 3

[0027] A kind of embodiment of the mouthwash that the present invention proposes, the weight percent of nimesulide in the mouthwash is 0.1%, the weight percent of sodium fluoride in the mouthwash is 0.1%, and the weight percent of lidocaine in the mouthwash is 2% ~4%, the weight percent of ethanol in the mouthwash is 10-20%, and the weight percent of sorbitol in the mouthwash is 10-20%.

[0028] The preparation method of mouthwash described in the present embodiment is:

[0029] According to the above proportions by weight, after fully mixing the proportions of the mouthwash components (the mouthwash components include at least nimesulide, sodium fluoride, lidocaine, ethanol and sorbitol) by stirring the magnet to mix evenly within the time range of 1 hour , Gradually add distilled water and further stir and mix at 20 degrees Celsius to form a clear liquid, and filter to remove impurities to obtain mouthwash. For example, the filtration procedure may be filtration through fil...

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PUM

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Abstract

The invention provides a multifunctional medical mouthwash and a preparation method thereof. The mouthwash at least comprises nimesulide, sodium fluoride, and the balance distilled water. The multifunctional medical mouthwash provided by the invention has multiple medical purposes of cleaning the oral cavity, relieving oral discomfort symptoms, diminishing inflammation and the like; the multifunctional medical mouthwash can also be used as adjuvant drugs before radioactive oral mucositis, chemotherapy-induced oral ulcer, recurrent aphthous ulcer, and oral cleaning or periodontal treatment, issuitable for prior oral treatment and post oral treatment, and has the efficacy of relieving pains after oral treatment.

Description

technical field [0001] The invention relates to the field of mouthwash, in particular to a multifunctional medical mouthwash and a preparation method thereof. Background technique [0002] The oral cavity is the main organ for eating. Oral ulcers can occur from self-limiting recurrent aphthous ulcers, or from oral mucositis caused by radiotherapy. In recent years, due to the chemotherapy drug methotrexate tablets Oral ulcers caused by use are also more common. The inflammation of the mucous membranes in the oral cavity is the biggest trouble for the patients, which causes pain, aggravates the difficulty of eating, causes great troubles to daily life, and becomes a mental burden. Since the oral cavity is the entrance of the digestive tract, the way of medication is limited, and the surface coating is also difficult to stay on the surface. Therefore, the relief of oral mucosal ulcers in the form of gargle can allow patients to obtain a certain relief from pain, restore relat...

Claims

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Application Information

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IPC IPC(8): A61K33/16A61K31/18A61K8/46A61K8/21A61P1/02A61Q11/00
CPCA61K8/21A61K8/46A61K31/18A61K33/16A61Q11/00A61P1/02A61K2300/00
Inventor 卓颖
Owner 卓颖
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