Application of lactobacillus plantarum powder in regulating fat metabolism and intestinal flora of obese rats

Abstract

The invention provides an application of lactobacillus plantarum powder in regulating fat metabolism and intestinal flora of fat rats. The lactobacillus plantarum powder can reduce the in-vivo fat content, increased under induction of high-fat diet, of rats and reduce the body fat rate; the FFA content, increased under induction of high-fat diet, in serum of rats can be remarkably reduced; meanwhile, the TG content in the serum of obese rats can be reduced, and the HDL-C content is increased; the lipid metabolism function of the livers of the obese rats can be improved, and activation of a fatty acid synthesis pathway of the obese rats is inhibited; the condition of intestinal flora disorder of the obese rats can be improved, and the flora richness, flora diversity, flora structure and composition of the obese rats can be maintained; increase of relative abundance of firmicutes is inhibited; the relative abundance of bacteroides is improved; the relative abundance ratio of the firmicutes to the bacteroides in intestinal tracts of rats under the condition of high fat diet is reduced; and the similarity of intestinal flora of the obese rats and healthy rats is increased.

Description

Technical field [0001] The invention belongs to the field of biological food, and specifically designs the application of plant lactobacillus powder to regulate fat metabolism and intestinal flora in obese rats. Background technique [0002] Obesity is a chronic metabolic disease, which not only directly affects human health, but may also cause secondary diseases such as hypertension and diabetes. In severe cases, it will accelerate aging and death. Genetics, environment, eating habits and other factors can cause body obesity, and high-fat eating habits are the main cause of acquired obesity. Compared with the ordinary diet, the outstanding feature of the high-fat diet is the high fat content. A large intake of high-fat diet can cause the body's lipid metabolism disorder, a large accumulation of fat, and cause intestinal flora disorders. [0003] Nowadays, most of the fast treatment of obesity diseases takes a certain dose of drugs, but most traditional western medicines or tradit...

AI Technical Summary

Problems solved by technology

[0003] Most of the rapid treatment of obesity now takes a certain dose of drugs, but most of the traditional western medicines or traditional Chinese medicines have certain side effects, and there are certain potential safety hazards. It has attracted more and more attention, but there are few reports on the specific role of Lactobacillus plantarum powder in regulating lipid metabolism or intestinal flora in the body

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