Dextran washing and sedimentation system

Abstract

The invention discloses a dextran washing and sedimentation system, and belongs to the technical field of dextran washing. The system is characterized in that a primary temperature control heat exchange device is additionally arranged between a washing sedimentation tank (2) and a coarse filter (5); the output end of the coarse filter (5) is connected with a hydrolysis tank (9) through a roots pump (8); an electric stirring device is arranged in the washing sedimentation tank (2), and one side of the lower part of the washing sedimentation tank (2) is connected with an alcohol input pipe (202). The temperature control heat exchange device, the coarse filter and the roots pump are additionally arranged on an output pipeline of the washing sedimentation tank. The temperature in the crude product output pipe is monitored and adjusted in real time through the temperature control heat exchange device, and the dextran crude product in the pipeline is heated in real time, so that the viscosity of the dextran crude product is effectively reduced, and the flowability of the dextran crude product is improved. The high temperature can obviously reduce the inclusion of dextran colloid on impurities, and is beneficial to filtering and removing large-particle impurities. Large-particle impurities in the dextran crude product are removed, the quality of dextran is improved, and the service lifetime of the roots pump is prolonged.

Description

technical field [0001] A dextran washing and precipitating system belongs to the technical field of dextran washing. Background technique [0002] At present, in the production process of dextran, it is usually necessary to wash and precipitate. In the washing and sedimentation tank, most of them use alcohol for washing. However, in the process of using alcohol to wash the fermentation product and obtain the crude dextran, due to the high concentration of ethanol, the precipitation of dextran colloids is fast. , Impurities are easily wrapped in the sedimentation particles, and finally form larger particles of high-viscosity dextran crude product. This kind of crude product has the following disadvantages: 1. The crude dextran product with high viscosity and wrapped with impurities is prone to agglomeration, adhesion to the inner wall of the pipeline, and adhesion to block the delivery pump during pipeline transportation, which affects the normal operation of the washing sedi...

AI Technical Summary

Problems solved by technology

This kind of crude product has the following disadvantages: 1. The crude dextran product with high viscosity and wrapped with impurities is prone to agglomeration, adhesion to the inner wall of the pipeline, and adhesion to block the delivery pump during pipeline transportation, which affects the normal operation of the washing sedimentation tank-hydrolysis tank delivery

2. The crude dextran product contains impurities, which can easily cause poor solubility and yellow color of the crude dextran product, and the yellow color and poor solubility of dextran will affect its quality as an injection drug

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