External use biological preparation for controlling vagina inflammation, and preparation method of external use biological preparation for controlling vagina inflammation

Abstract

The invention discloses an external use biological preparation for controlling vagina inflammation, wherein the acid environment with pH smaller than or equal to 4.5 of the vagina can be maintained, and the external use biological preparation has higher buffer capacity and good sterilizing effects and is non-irritant. The external use biological preparation consists of the following raw materialsin percentage by mass of 1-5% of a radix sophorae flavescentis extract, 1-5% of a poria cocos extract, 0.1-2% of a radix angelica sinensis extract, 0.1-2% of a wild chrysanthemum extract, 0.1-2% of awhite lily extract, 0.1-2% of a hamamelis extract, 0.1-2% of a calendula extract, 1-10% of 1,3-butanediol, 0.1-2% of hydroxyethyl cellulose, 0.1-2% of ammonium acryloyldimethyltaurate/VP copolymers, 0.1-2% of ethylenediamine tetraacetic acid disodium salt, 0.1-10% of antibacterial peptides and the balance water.

Description

technical field [0001] The present invention relates to a medicine for preventing and treating female reproductive tract inflammation, especially a kind of external biological preparation for preventing and treating vaginal inflammation which can maintain the acidic environment of vaginal pH ≤ 4.5, has strong buffer capacity and bactericidal effect, and is non-irritating. its preparation method. Background technique [0002] Female reproductive tract infection (Reproductive Tract Infection, RTI) is mainly an infectious disease that occurs in the female reproductive system, and is caused by various pathogenic microorganisms such as parasites, viruses, bacteria, fungi, and chlamydia. Gram-positive Lactobacilli are the dominant bacteria in the normal female reproductive tract flora. Lactobacillus decomposes glycogen in the vaginal mucosa epithelium in an acidic environment to produce lactic acid, and at the same time produces hydrogen peroxide and lactobacillus, which can effec...

AI Technical Summary

Problems solved by technology

Antibiotics have the best antibacterial effect, but they have the problem of destroying the self-cleaning function of the vagina and causing the imbalance of normal vaginal flora; Chinese medicine extracts also have good curative effects, but their pH is about 7.5, which will not only affect the gram-positive lactic acid The growth of dominant bacteria such as bacilli has a certain impact on the self-cleaning function of the vagina, and it is more irritating to the skin, sometimes causing side effects such as skin redness and swelling; the pH of the antibacterial peptide is about 3.8, which is conducive to vaginal self-cleaning, but the antibacterial effect is relatively weak

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