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Traditional Chinese medicine composition for promoting diabetic ulcer wound repair and preparation method of traditional Chinese medicine composition

A technology for repairing diabetic ulcers and wounds, which can be used in drug combination, drug delivery, pharmaceutical formulations, etc., to solve problems such as unfavorable ulcer closure, affecting the integrity and normal functional activities of the affected limb, and slow progress, achieving high patient compliance, Not easy to stick to the skin, fast closing effect

Inactive Publication Date: 2020-05-22
HUADONG HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, surgical treatment can easily affect the integrity of the affected limb and normal functional activities, while non-surgical treatment, including drugs and physical therapy, slows down the epithelialization process of the wound, which is not conducive to ulcer closure

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1 Chinese medicine composition of the present invention treats clinical experiment of diabetic ulcer

[0032] Take 120 parts of trichosanthum pollen, 90 parts of turmeric, 90 parts of rhubarb, 24 parts of herb, 24 parts of Magnolia officinalis, 90 parts of Angelica dahurica, 60 parts of frankincense, 60 parts of myrrh, 90 parts of keel, 100 parts of beeswax, and 900 parts of sesame oil.

[0033] Preparation:

[0034] (1) take each raw material by weight;

[0035] (2) making raw material 1 after the keel is ground into powder for subsequent use;

[0036] (3) Soak trichosanthum pollen, turmeric, rhubarb, atractylodes rhubarb, Magnolia officinalis, and Angelica dahurica together in a sesame oil pot for 72 hours, then heat to 165°C, keep warm for 25 minutes, and the color becomes burnt yellow, remove residue and filter, and filter after cooling to obtain filtrate I ;

[0037] (4) Heating the filtrate I to 170°C, adding frankincense and myrrh to dissolve it, re...

Embodiment 2

[0040] Embodiment 2 treats the Chinese medicine composition of diabetic ulcer

[0041] Take 120 parts of trichosanthum pollen, 90 parts of turmeric, 85 parts of rhubarb, 24 parts of atractylodes rhubarb, 24 parts of Magnolia officinalis, 80 parts of Angelica dahurica, 60 parts of frankincense, 60 parts of myrrh, 90 parts of keel, 100 parts of beeswax, and 900 parts of sesame oil.

[0042] Preparation:

[0043] (1) take each raw material by weight;

[0044] (2) making raw material 1 after the keel is ground into powder for subsequent use;

[0045] (3) Soak trichosanthum pollen, turmeric, rhubarb, atractylodes rhubarb, Magnolia officinalis, and Angelica dahurica together in a sesame oil pot for 50 hours, then heat to 160°C, keep warm for 22 minutes, and the color becomes burnt yellow, remove residue and filter, cool down and filter to obtain filtrate I ;

[0046] (4) Heating the filtrate I to 150°C, adding frankincense and myrrh to dissolve it, removing residue and filtering,...

Embodiment 3

[0049] Embodiment 3 treats the Chinese medicine composition of diabetic ulcer

[0050] Take 120 parts of trichosanthes, 90 parts of turmeric, 90 parts of rhubarb, 27 parts of herb, 24 parts of Magnolia officinalis, 80 parts of Angelica dahurica, 60 parts of frankincense, 60 parts of myrrh, 90 parts of keel, 100 parts of beeswax, and 900 parts of sesame oil.

[0051] Preparation:

[0052] (1) take each raw material by weight;

[0053] (2) making raw material 1 after the keel is ground into powder for subsequent use;

[0054] (3) Soak trichosanthum, turmeric, rhubarb, atractylodes rhubarb, Magnolia officinalis, and Angelica dahurica together in a sesame oil pot for 60 hours, then heat to 155°C, keep warm for 22 minutes, and the color becomes burnt yellow, remove residue and filter, and filter after cooling to obtain filtrate I ;

[0055] (4) Filtrate I was heated to 155° C., frankincense and myrrh were added, slag was removed and filtered, and filtrate II was obtained by filt...

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Abstract

The invention provides a traditional Chinese medicine composition for promoting diabetic ulcer wound repair and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 100-150 parts of radix trichosanthis, 70-110 parts of rhizoma curcumae longae, 70-110 parts of radix et rhizoma rhei, 20-30 parts of rhizoma atractylodis, 20-30 parts of cortex magnoliae officinalis, 70-110 parts of radix angelicae dahuricae, 50-75 parts of olibanum, 50-75 parts of myrrha, 70-110 parts of os draconis, 100-150 parts of cera flava and 750-1000 parts of oleum sesami. According to the traditional Chinese medicine compound preparation, traditional Chinese medicines are utilized to achieve ahooping effect, diffuse swelling around diabetic ulcer skin is promoted to be astringed and gathered to a wound, and an effect of treating dispersion with astringent is achieved, so that gathered toxic pathogens penetrate out of a body from the ulceration wound to form a protection field, and healing of the wound is accelerated. The traditional Chinese medicine compound preparation for external use has the characteristics and advantages of no operation, low pain, quick wound astringing and high patient compliance, and meanwhile, advantages of an external treatment method with the characteristics of the traditional Chinese medicines are embodied.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for promoting diabetic ulcer wound repair and a preparation method thereof. Background technique [0002] Diabetic ulcers are serious and common among many complications of diabetes [1-2] In recent years, the incidence rate in North America and Europe is 13%, 5.1% [3] , the incidence rate in China has reached 8.1% [4] . High medical expenses cause huge economic burden to the society. At present, diabetic ulcers are mostly treated with wound dressing changes, infection control, hyperbaric oxygen therapy, surgery, etc. [5] . However, surgical treatment can easily affect the integrity of the affected limb and normal functional activities, while non-surgical treatment, including drugs and physical therapy, slows down the process of epithelialization of the wound, which is not conducive to ulcer closure....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/06A61P3/10A61P17/02A61K35/02A61K35/644
CPCA61K9/0014A61K9/06A61K35/02A61K35/644A61K36/185A61K36/232A61K36/284A61K36/324A61K36/328A61K36/428A61K36/575A61K36/708A61K36/9066A61K2236/35A61P3/10A61P17/02A61K2300/00
Inventor 吴闽枫黄建华王宏伟
Owner HUADONG HOSPITAL
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