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Preparation of tea tree essential oil inclusion compound and gasified inhalation type administration method of tea tree essential oil inclusion compound

The technology of a tea tree essential oil and an administration method, which is applied in the field of traditional Chinese medicine, can solve the problems of easy decomposition and deterioration, and the essential oil is easy to volatilize, and achieves the effects of small dosage of medicine, convenient use and convenient carrying.

Inactive Publication Date: 2020-05-12
YUNNAN LVXIN BIOLOGICAL PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, essential oils are volatile, sensitive to light, temperature, and air, and easy to decompose and deteriorate

Method used

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  • Preparation of tea tree essential oil inclusion compound and gasified inhalation type administration method of tea tree essential oil inclusion compound

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Tea tree essential oil clathrate

[0023] (1) Take 40g of pure gum and 160mL of water to make a pure gum solution, the mass volume ratio of pure gum to water is 1:4g / mL.

[0024] (2) Under stirring conditions, slowly add 10 mL of tea tree essential oil into the pure gum solution obtained in step (1) for emulsification, the mass volume ratio of tea tree essential oil and pure gum is 1:4mL / g.

[0025] Using a high-shear homogeneous emulsifier, circulate emulsification twice at 30~40Mpa to make the mixture into a uniform emulsion. Spray drying at an inlet air temperature of 190±5°C and an outlet air temperature of 85±5°C. After drying, dry tea tree essential oil clathrate is obtained.

Embodiment 2

[0027] Tea tree essential oil clathrate

[0028] (1) Take 50g of pure gum and 300mL of water to make a pure gum solution, the mass volume ratio of pure gum to water is 1:6g / mL.

[0029] (2) Under stirring conditions, slowly add 10 mL of tea tree essential oil into the pure gum solution obtained in step (1) for emulsification, the mass volume ratio of tea tree essential oil and pure gum is 1:5mL / g.

[0030] Using a high-shear homogeneous emulsifier, circulate emulsification twice at 30~40Mpa to make the mixture into a uniform emulsion. Spray drying at an inlet air temperature of 190±5°C and an outlet air temperature of 85±5°C. After drying, dry tea tree essential oil clathrate is obtained.

Embodiment 3

[0032] Tea tree essential oil clathrate

[0033] (1) Take 60g of pure gum and 480mL of water to make a pure gum solution, the mass volume ratio of pure gum to water is 1:8g / mL.

[0034] (2) Under stirring conditions, slowly add 10 mL of tea tree essential oil into the pure gum solution obtained in step (1) for emulsification. The mass volume ratio of tea tree essential oil and pure gum is 1:6 mL / g.

[0035] Using a high-shear homogeneous emulsifier, circulate emulsification twice at 30~40Mpa to make the mixture into a uniform emulsion. Spray drying at an inlet air temperature of 190±5°C and an outlet air temperature of 85±5°C. After drying, dry tea tree essential oil clathrate is obtained.

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Abstract

The invention provides preparation of a tea tree essential oil inclusion compound and a gasified inhalation type administration method of the tea tree essential oil inclusion compound. Tea tree essential oil has good broad-spectrum bactericidal bacteriostatic and health care actions and is considered as an important substitute of local antimicrobial agents of antibiotics. According to the preparation and the gasified inhalation type administration method, the tea tree essential oil is included with pure gelatin, administration is carried out by using an electronic heater, the tea tree essential oil inclusion compound can be gasified when a heating temperature exceeds boiling points of compounds in the tea tree essential oil, a sufferer inhales gas into an oral cavity in a smoking manner, the gas enters a respiratory tract, thus, bacteriostatic and bactericidal effects of the tea tree essential oil are exerted, and the tea tree essential oil inclusion compound can be applied to adjuvanttherapy of diseases of respiratory tract infection.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to the preparation of tea tree essential oil clathrate and its gasification and inhalation administration method. Background technique [0002] Tea tree essential oil (volatile oil), also known as Melaleuca alternifolia oil, is a colorless to pale yellow oily liquid extracted from fresh branches and leaves of Melaleuca alternifolia by steam distillation. Human aroma. At present, it has been widely used in basic medicine and health, daily chemical industry, spices, food, pharmaceutical and other industries. [0003] Tea tree essential oil has good broad-spectrum bactericidal and antibacterial properties, can resist viruses, activate immune factors, resist parasites, and promote wound healing. Irregular menstruation and genital infection. It is non-toxic and pollution-free, has the advantages of low drug resistance and safety to the human body, and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/61A61K47/69A61K9/72A61P11/00A61P31/04A61P31/12A61P31/10A61P33/00
CPCA61K9/0053A61K36/61A61K47/6949A61P11/00A61P31/04A61P31/10A61P31/12A61P33/00
Inventor 刘胜贵王钲霖马海悦付彬彬李智高孔令羽
Owner YUNNAN LVXIN BIOLOGICAL PHARMA CO LTD
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