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Temperature-based real-time evaluation method and temperature-based real-time evaluation device for Young's modulus of microwave ablation tissue

A microwave ablation and Young's modulus technology, which is applied to microwave surgical instruments, control instrument energy, and components of surgical instruments, etc., can solve problems such as the absence of an effective relationship model between microwave ablation temperature and Young's modulus.

Active Publication Date: 2020-04-10
NANJING NUOYUAN MEDICAL DEVICES CO LTD
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

[0005] There is currently no valid relationship model between temperature and Young's modulus during microwave ablation

Method used

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  • Temperature-based real-time evaluation method and temperature-based real-time evaluation device for Young's modulus of microwave ablation tissue
  • Temperature-based real-time evaluation method and temperature-based real-time evaluation device for Young's modulus of microwave ablation tissue
  • Temperature-based real-time evaluation method and temperature-based real-time evaluation device for Young's modulus of microwave ablation tissue

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Embodiment Construction

[0033] Below in conjunction with embodiment the present invention will be further described.

[0034] like figure 1 Shown is a flow chart of a temperature-based microwave ablation tissue Young's modulus real-time evaluation method provided by an embodiment of the present invention, including the following steps:

[0035] S1. Build a simultaneous real-time acquisition system for microwave ablation temperature and Young's modulus;

[0036] S2. Obtain data on the synchronous change of T and E under different ablation doses;

[0037] S3, establish multiple groups of E-T relational equations by polynomial data fitting, according to the coefficient of determination (goodness of fit, R) of each group of relational equations obtained 2 ), remove R 2 <0.9 relational equation;

[0038] S4. Utilize satisfying R 2 Multiple sets of E-T relationship equations ≥0.9 are averaged to obtain the final E-T relationship model;

[0039] S5, check the established E-T relationship model, determ...

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Abstract

The invention discloses a temperature-based real-time evaluation method and a temperature-based real-time evaluation device for the Young's modulus of a microwave ablation tissue. The method can be used to estimate the hardness parameter (Young's modulus, E) of the tissue in real time according to an obtained temperature (T) of the tissue in a microwave ablation process. According to the method, firstly, a large amount of synchronous change data of T and E in the microwave ablation process is acquired by building an in-vitro pig liver microwave ablation temperature and Young's modulus real-time synchronous acquisition system; and secondly, a plurality of groups of E-T relation equations are established by data fitting to acquire a final E-T relation model. The method establishes correlation between T and E, and can calculate the hardness parameter of the tissue by measuring the temperature of the tissue. The method has great significance for evaluating the real-time curative effect ofmicrowave ablation of tumors, and has important values for establishing a multi-mode microwave ablation curative effect evaluation system.

Description

technical field [0001] The invention belongs to the technical field of evaluating the curative effect of microwave ablation, and in particular relates to a temperature-based real-time evaluation method and device for microwave ablation tissue Young's modulus. Background technique [0002] Microwave thermal ablation therapy is considered to be another new type of effective treatment for malignant tumors after surgery, chemotherapy, radiotherapy, immunotherapy, etc. It has played a huge role in tumor treatment and has been widely used in common tumors such as liver cancer, lung cancer, kidney cancer, thyroid cancer, intestinal cancer, and uterine fibroids. However, there are still many scientific and technical problems to be solved in microwave tumor thermal ablation, one of the most important ones is the real-time curative effect evaluation problem in microwave ablation therapy. At present, temperature is mainly used as a determining factor for tumor cell inactivation in cli...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/18
CPCA61B18/1815A61B2018/00791A61B2018/00904
Inventor 钱志余晋晓飞刘文文李怡燃王娟冯宇俞钦栋朱柔君邹止寒
Owner NANJING NUOYUAN MEDICAL DEVICES CO LTD
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