Inclusion preparation of traditional Chinese medicine composition with anti-tumor effect and preparation method and application of inclusion preparation

Abstract

The invention discloses an inclusion preparation of a traditional Chinese medicine composition with an anti-tumor effect. The inclusion preparation is prepared from traditional Chinese medicinal materials and auxiliary materials, wherein the traditional Chinese medicinal materials comprise American ginseng, venenum bufonis, asparagus cochinchinensis, rhizoma bolbostemmae, acanthopanax obovatus hoo, kiwi root, fructus hippophae and fingered citron; and the auxiliary materials comprise sucralose, sorbitol, xylitol and a spicy sense covering agent. An optimal extraction process of the various rawmaterials is screened through a large number of experiments; the optimal auxiliary materials are screened; the novel inclusion preparation of Tianfoshen oral liquid with reasonable process design isprovided; and by the preparation, the defects of spicy sense, bitter and lasting aftertaste, high sugar content, difficulty in popularization and taking and the like of the Tianfoshen oral liquid canbe greatly overcome. Meanwhile, pilot scale production proves that the preparation method provided by the invention is simple in process, good in preparation stability, high in content of extracted effective components, high in operability and suitable for industrial mass production.

Description

technical field [0001] The invention relates to a medicine, in particular to a traditional Chinese medicine composition, its preparation method and its application in the preparation of medicines for treating tumor diseases. Background technique [0002] Malignant tumors have become a common and major disease that seriously threatens human life and quality of life. The causes of malignant tumors mainly include: environmental pollution of the body, chemical pollution, such as chemical toxins, ionizing radiation, free radical toxins, microorganisms, such as bacteria, fungi, viruses, etc. and their metabolic toxins, genetic characteristics, endocrine imbalance, immune dysfunction, etc. Various carcinogens and carcinogenic factors lead to cancerous changes in normal cells of the body. It often manifests as: a local mass formed by abnormal proliferation of cells in local tissues. Cancer is a large class of diseases caused by multiple reasons, multiple stages and multiple mutatio...

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Problems solved by technology

[0004] At present, there are many means and methods for the treatment of malignant tumors, such as surgery, chemotherapy, radiotherapy, immunotherapy, etc. These treatments have certain curative effects on malignant tumors, but at the same time, there are serious adverse reactions and limited efficacy. and other shortcomings

[0005] Tianfushen Oral Liquid produced by Changshu Leiyunshang Pharmaceutical Co., Ltd. has significant anti-tumor effect, but due to its high sugar content, it is not suitable for cancer patients with diabetes. The viscosity is also high, which is inconvenient for weaker tumor patients to inhale, and the toad in the prescription has a spicy feeling, and the aftertaste is bitter and long-lasting, making it difficult to take, which affects its clinical application

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