Preparation method and application for oral solution containing Panax ginseng, Codonopsis pilosula, radix scrophulariae, radix ginseng Rubra, radix salviae miltiorrhizae and astragalus membranaceus

A filtrate, protein-free technology, applied in the field of medicine, can solve the problems of undisclosed effects and research, and achieve the effect of obvious effect and obvious therapeutic effect.

Active Publication Date: 2020-02-21
HUBEI WEISHI BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no research on the treatment of gastric ulcer with Wushenqi Oral Liquid, and there is no published research on the effect and research on the preparation process of porcine protein-free serum in Wushenqi Oral Liquid on its efficacy in treating gastric ulcer

Method used

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  • Preparation method and application for oral solution containing Panax ginseng, Codonopsis pilosula, radix scrophulariae, radix ginseng Rubra, radix salviae miltiorrhizae and astragalus membranaceus
  • Preparation method and application for oral solution containing Panax ginseng, Codonopsis pilosula, radix scrophulariae, radix ginseng Rubra, radix salviae miltiorrhizae and astragalus membranaceus

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preparation example Construction

[0017] 1. Preparation of porcine protein-free serum

[0018] In order to obtain porcine protein-free serum that meets the requirements, it will be prepared through pretreatment, column mixed bed treatment, ultrafiltration treatment and post-treatment.

[0019] A preparation method of pig protein-free serum, comprising the following steps:

[0020] Pretreatment: Take pig blood for anticoagulation treatment, add purified water to adjust the pH value, add adsorbent for adsorption, heat and boil for denaturation treatment, and collect the first filtrate by filtration;

[0021] Column mixed bed treatment: the first filtrate is concentrated to obtain a first concentrated liquid, and after centrifugation, the supernatant is taken, passed through a column mixed bed, and the effluent is collected, and the effluent is filtered to obtain a second filtrate;

[0022] Ultrafiltration treatment: passing the second filtrate through an ultrafiltration column to collect the permeate;

[0023]...

Embodiment 1

[0034] Example 1: 10 parts of porcine protein-free serum, 20 parts of ginseng, 10 parts of astragalus, 10 parts of codonopsis, 8 parts of crocodile, 4 parts of red ginseng, 5 parts of safflower, 5 parts of Ophiopogon japonicus, 15 parts of Schisandra chinensis in Example 1 , 8 parts of Acanthopanax, 5 parts of Banzhilian, 5 parts of Salvia, 3 parts of Lycium barbarum, 3 parts of Rehmannia glutinosa and 3 parts of honey.

Embodiment 2

[0035] Example 2: 20 parts of pig protein-free serum, 10 parts of ginseng, 8 parts of astragalus, 7 parts of codonopsis, 7 parts of crocodile, 8 parts of red ginseng, 10 parts of safflower, 3 parts of Ophiopogon japonicus, 1 part of Schisandra chinensis in Example 1 , Acanthopanax 5 parts, Scutellaria barbata 3 parts, Salvia miltiorrhiza 1 part, Lycium barbarum 1 part, Rehmannia glutinosa 2 parts and honey 2 parts.

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PUM

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Abstract

The invention discloses a preparation method and an application for an oral solution containing Panax ginseng, Codonopsis pilosula, radix scrophulariae, radix ginseng Rubra, radix salviae miltiorrhizae and astragalus membranaceus. The preparation method for porcine protein-free serum comprises the following steps: taking pig blood for anticoagulation treatment and denaturation treatment, and collecting a first filtrate; concentrating the first filtrate so as to obtain a first concentrate, carrying out centrifuging, allowing a supernate to flowing into a column mixing bed, collecting an effluent liquid, and carrying out filtering so as to obtain a second filtrate; allowing the second filtrate to flow through an ultrafiltration column, and collecting a permeate; and concentrating the permeate so as to obtain a second concentrate, adding medicinal active carbon, carrying out adsorption treatment, carrying out heating to 80 DEG C, carrying out filtering, blending the filtrate, filling thefiltrate into an oral liquid bottle, carrying out sealing and sterilizing, and carrying out storing in a shade place. The porcine protein-free serum obtained by using the preparation method provided by the invention reaches a dry matter content and a trace element content respectively up to 75.1% and 0.092%, and has trace elements with a content higher than the average level of the trace elementscontained in human serum. The porcine protein-free serum provided by the invention is used for preparing the oral solution containing Panax ginseng, Codonopsis pilosula, radix scrophulariae, radix ginseng Rubra, radix salviae miltiorrhizae and astragalus membranaceus, and has obvious treatment effects on gastric ulcer and duodenal ulcer.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a preparation method and application of Wushenqi oral solution. Background technique [0002] Wushenqi Oral Liquid is formulated with ginseng, Codonopsis radix, Scrophulariaceae, red ginseng and Salvia miltiorrhiza as the five ginseng, supplemented with astragalus and porcine protein-free serum. It is used for shortness of breath, laziness, fatigue, dizziness, soreness of the waist and knees caused by deficiency of qi and blood and deficiency of kidney yang. It can also enhance the body's immunity, nourish the lungs and kidneys, and has obvious effects on lung cancer and liver cancer. inhibition. Clinically, it has curative effects on chronic cough due to lung deficiency, asthma, hemoptysis due to tuberculosis, night sweat, waist and knee pain due to kidney deficiency, impotence and nocturnal emission, neurasthenia, and red blood cell drop after chemotherapy and radiotherapy. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/08A61P1/04A61K35/644A61K35/16
CPCA61K35/16A61K36/258A61K36/481A61K36/344A61K36/808A61K36/286A61K36/8968A61K36/79A61K36/57A61K36/254A61K36/539A61K36/537A61K36/815A61K36/804A61K35/644A61K9/0095A61P1/04A61K2300/00
Inventor 罗先隽
Owner HUBEI WEISHI BIO PHARMA
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