Wireless wearable neural signal detectiondevice and system

Abstract

The invention discloses a wireless wearable neural signal detectiondevice and system. The device includes a flexible microelectrode array and a wearable detector, wherein the flexible microelectrode array can be implanted into nervous nuclei in the brain, and is applied to synchronous detection of neural electrophysiological signals and neural electrochemical signals, the wearable detector is usedfor receiving the neural electrophysiological signals and neural electrochemical signals which are output by the flexible microelectrode array, performing conditioning analysis, analog-to-digital conversion and compression on the neural electrophysiological signals and neural electrochemical signals and sending the compressed signals in a wireless mode. Unrestricted free movement and behavior ofanimals are facilitated in the research, and the problem of difficult movement of the animals duringcontinuous monitor of neural information in the research of behavioral neural mechanisms of the animals can besolved.

Description

technical field [0001] The invention relates to the field of neural information detection in brain science, in particular to a wireless wearable neural signal detection device and system. Background technique [0002] Combining behavioral studies with neural circuit mechanisms is an important direction of brain science research. Take sleep as an example: sleep is a complex behavioral activity under the control of brain nerves, which can relieve fatigue and help remove waste in brain cells. Synaptic remodeling enhances learning and memory abilities, etc. However, at present, the sleep disorder manifested by insomnia has a global prevalence rate of 6-10%, and the incidence rate is increasing day by day, and has become an important medical and public health problem involving all mankind. Insomnia can have adverse effects on the human body and spirit. It can be one of the earliest and most common symptoms of depression, and it is also one of the factors leading to depression, w...

AI Technical Summary

Problems solved by technology

However, the existing neuroelectrophysiological technology and transmitter detection technology cannot fully meet the needs of long-term continuous monitoring of neuroelectricity and glutamate and other transmitter concentration signals in the animal brain without restraining animal behavior.

On the one hand, using the existing mainstream wired connection method to monitor the neural information activity in the brain will disturb and restrict the animal's behavior, which will bring artificial interference factors and a lot of inconvenience to the research; and Transmitter Electrochemical Signaling Wireless Wearable Instruments

On the other hand, the traditional silicon-based implanted microelectrode array, because it is rigid, will bring difficulties to long-term detection

First, after being implanted into the animal brain, it is easy to break due to animal activities; second, after long-term implantation, it is easy to cause inflammatory reactions, etc., resulting in brain cell death, causing the electrodes to be wrapped and eroded by secretions, resulting in electrode damage. Decreased performance, especially at transmitter concentration detection sites

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