Cortex eucommiae extract composition for treating gestational hypertension and application of cortex eucommiae extract composition

Abstract

The invention belongs to the field of traditional Chinese medicine extracts, and particularly relates to a cortex eucommiae extract composition for treating gestational hypertension and an applicationof the cortex eucommiae extract composition. The composition comprises 20-40 parts of ursolic acid, 10-25 parts of chlorogenic acid, 20-60 parts of a mixing extract of pinoresinol diglucoside and liriodendrin, and 30-50 parts of total flavone. The cortex eucommiae extract composition is prepared through the steps of enzymolysis, multiple-step extraction, dissolving and the like. The preparation method is simple and efficient, the prepared cortex eucommiae extract composition has good effect in the respect of treating gestational hypertension, and besides, the side effect is reduced.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine extracts, and in particular relates to an extract composition of Eucommia ulmoides for treating pregnancy-induced hypertension and its application. Background technique [0002] Gestational hypertension refers to the symptoms of high blood pressure, edema, proteinuria and other symptoms in women after 20 weeks of pregnancy, which are transient and disappear after delivery. It is a pregnancy-specific disease and is one of the main causes of maternal and perinatal illness and death. Hypertension must be considered if the systolic blood pressure is above 140 mm Hg (18.7 kPa) and the diastolic blood pressure is above 90 mm Hg (12.0 kPa) in the third trimester of pregnancy. There are many theories about the causes of pregnancy-induced hypertension. It is generally believed that certain substances from the placenta enter the maternal blood, causing changes in the immune factors of the pregna...

AI Technical Summary

Problems solved by technology

[0006] Chinese patent application CN 102670791 A discloses a traditional Chinese medicine oral liquid of Eucommia ulmoides for relieving hypertension, which is made of the following raw materials in parts by weight: 150-300 parts of Eucommia ulmoides, 150-300 parts of angelica, 150-300 parts of Morinda officinalis , Polygonum multiflorum 150-300 parts, lotus leaf 150-300 parts, the oral liquid can quickly relieve symptoms such as tinnitus, dizziness, headache, palpitation, shortness of breath, insomnia caused by high blood pressure, but due to the large number of components, there is no effect on the active ingredients In the process of separation and purification, the impurities and harmful components in the components of traditional Chinese medicine cannot be effectively eliminated

[0007] Chinese patent application CN 103750156 A discloses a low-cost, rich in active substances such as genipinic acid and aucubin, which are also rich in nutrients such as amino acids and glucose, and can reduce the vermicelli of Eucommia ulmoides gum. The processing method can be used in prevention and diet, but its effect in the treatment of pregnancy-induced hypertension needs to be further improved