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Anti-acne composition and preparation method thereof

A composition and an acne-removing technology, applied in the field of biomedicine, can solve problems such as inability to meet actual needs, and achieve the effects of relieving and treating acne, reducing drug resistance enhancement, and enhancing inhibitory effect.

Pending Publication Date: 2019-11-05
王鹏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with the enhancement of bacterial resistance, the use of tea tree oil alone for acne treatment can no longer meet the actual needs, and it is urgent to develop a drug that can more effectively inhibit the proliferation of bacteria such as Propionibacterium acnes to meet the needs.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] 1. Preparation of magnolol essential oil, magnolol and honokiol

[0045] Get Magnolia officinalis (Magnolia officinalis (Magnolia officinalis) dry dry bark, root bark or branch bark), after crushing, Magnolia officinalis powder is obtained, and Magnolia officinalis powder is put into a round-bottomed retort, and in the round-bottomed retort Add deionized water in the middle, carry out normal pressure distillation to Magnolia officinalis powder. Add 15ml of deionized water to every 1g of magnolia bark powder, continue the atmospheric distillation for 2h, recover the distillate from the receiver after the end, and recover the medicinal residue from the round bottom distillation bottle. After using anhydrous sodium sulfate to dehydrate the distillate, take the oil phase to obtain Magnolia officinalis essential oil.

[0046] Medicinal residues are placed in the round bottom flask, use 80% alkaline ethanol to extract medicinal residues (heat reflux extraction), the add-on o...

Embodiment 2

[0052] This embodiment is basically the same as Example 1, the difference being the preparation process of the acne-removing composition:

[0053] The raw materials are mixed according to the following parts by weight: 100 parts of tea tree essential oil, 180 parts of magnolol essential oil, 140 parts of magnolol, 80 parts of honokiol, 60 parts of peppermint oil, 120 parts of fennel essential oil, 40 parts of helichrysum essential oil and 70 parts of clove basil oil to obtain a mixture, then add the mixture into the solubilizer SP-115A, stir evenly, then add deionized water, and mix evenly to obtain the acne-removing composition. Among them, 50ml of deionized water and 30ml of SP-115A are added to every 10g of the mixture.

Embodiment 3

[0055] This embodiment is basically the same as Example 1, the difference being the preparation process of the acne-removing composition:

[0056] The raw materials are mixed according to the following parts by weight: 140 parts of tea tree essential oil, 140 parts of magnolol essential oil, 100 parts of magnolol, 80 parts of honokiol, 100 parts of peppermint oil, 120 parts of fennel essential oil, 80 parts of helichrysum essential oil and 30 parts of clove basil oil to obtain a mixture. Then the mixture was added into deionized water, and Span 60 was added into the water, and at a temperature of 80° C., it was vigorously stirred and emulsified to obtain an acne-removing composition. Wherein, 50 ml of deionized water and 30 ml of Span 60 were added to every 10 g of mixture A.

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Abstract

The invention belongs to the field of biomedicine and specifically relates to an anti-acne composition and a preparation method thereof. the anti-acne composition comprises the following raw materials(by weight): 100-140 parts of camellia sinensis essential oil, 140-180 parts of magnolia cortex essential oil, 100-140 parts of magnolol, 80-120 parts of honokiol, 60-100 parts of oleum menthae piperitae, 80-120 parts of chinese mosla herb essential oil, 40-80 parts of Helichrysum Italicum essential oil and 30-70 parts of Oleum Ocimi Gratissimi. The anti-acne composition effectively inhibits multiplication of bacteria such as propionibacterium acnes, etc., to realize treatment and prevention of acne. The anti-acne composition of the scheme can be applied to research and development and preparation of anti-acne products.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to an acne-removing composition and a preparation method thereof. Background technique [0002] Acne (acne) is a chronic inflammatory skin disease of the pilosebaceous unit. The pathogenesis of acne is multifaceted. Factors such as excessive sebum secretion, pilosebaceous duct blockage, and bacterial infection can cause acne. Among them, bacterial infection is the most important factor that acne takes place. On the skin surface and in the sebaceous follicles, there are some microorganisms including Propionibacterium acnes. The lipase produced by Propionibacterium acnes decomposes sebum to generate free fatty acids, and at the same time chemoattracts inflammatory cells and mediators, and finally induces and aggravates the inflammatory response. [0003] Tea tree essential oil is a substance with anti-acne effect, also known as Melaleuca alternifolia oil, which is extracted fr...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61P17/10A61K31/05
CPCA61K36/61A61K36/575A61K31/05A61K36/534A61K36/53A61K36/28A61P17/10A61K2236/37A61K2236/331A61K2236/333
Inventor 王鹏郑钟祥
Owner 王鹏
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