Pharmaceutical composition for treating stubborn acne and application thereof

A combination and stubborn technology, applied in the direction of drug combination, drug delivery, pharmaceutical formulation, etc., can solve problems such as scars, unsatisfactory effects, sepsis, etc.

Inactive Publication Date: 2019-10-18
岳茂兴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some people do not take scientific treatment methods after having pimples, but blindly pick and squeeze them with their hands, thinking that the pimples will be healed after the pimples are squeezed out, and the pimples will be cured when the pimples become deflated. Scars and pits on the skin, especially the acne in the triangle area of ​​the mouth and nose, can easily cause sepsis after being squeezed, and sometimes even life-threatening
[0004] 2. Possible causes of intractable acne: Acne is generally seen in young men and women often accompanied by seborrhea. After puberty, it usually heals or alleviates naturally. Chemical factors, unhygienic squeezing by hands, high mental stress and other factors, develop into blackheads, inflammatory papules, secondary abscesses or nodules, which are gradually difficult to heal and gradually aggravate, which has a great impact on work and life, and is urgently ill Indiscriminate medical treatment, abuse of antibiotics and hormones
[0016] Under normal circumstances, patients with severe or intractable acne need comprehensive treatment, but the effect of the comprehensive treatment currently used is still unsatisfactory
[0017] In summary, there is currently no safe, effective and low-cost drug for intractable acne at home and abroad.

Method used

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  • Pharmaceutical composition for treating stubborn acne and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Embodiment 1: Preparation example of pharmaceutical composition

[0074] A pharmaceutical composition, its component is:

[0075] Compound amino acid: containing 2.20g of isoleucine, 3.40g of leucine, 2.65g of lysine acetate, 0.30g of methionine, 0.40g of phenylalanine, 1.15g of threonine, and 0.38 of tryptophan g, valine 2.65g, arginine 2.20g, histidine 1.18g, glycine 1.57g, alanine 2.08g, proline 1.78g, aspartic acid 0.63g, asparagine 0.14g, N-acetyl-L-cysteine ​​0.20g, glutamic acid 1.43g, ornithine hydrochloride 0.42g, serine 0.93g, N-acetyl-L-tyrosine 0.22g, made into 250ml liquid;

[0076] Vitamins: Vitamin B 6 Add 3g and vitamin C 2g to 250ml 0.9% sodium chloride injection;

[0077] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0078] Compound amino acids, vitamins, and calcium gluconate can be divided into three groups and formulated for intravenous infusion sequentially; compound amino acids and vit...

Embodiment 2

[0079] Embodiment 2: Preparation example of pharmaceutical composition

[0080] A pharmaceutical composition, its component is:

[0081] Compound amino acid: containing 2.20g of isoleucine, 3.40g of leucine, 2.65g of lysine acetate, 0.30g of methionine, 0.40g of phenylalanine, 1.15g of threonine, and 0.38 of tryptophan g, valine 2.65g, arginine 2.20g, histidine 1.18g, glycine 1.57g, alanine 2.08g, proline 1.78g, aspartic acid 0.63g, asparagine 0.14g, N-acetyl-L-cysteine ​​0.20g, glutamic acid 1.43g, ornithine hydrochloride 0.42g, serine 0.93g, N-acetyl-L-tyrosine 0.22g, made into 250ml liquid;

[0082] Vitamins: Vitamin B 6 Add 3-5g and 2g of vitamin C to 250ml 0.9% sodium chloride injection;

[0083] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0084] Compound amino acids, vitamins, calcium gluconate, and Rocephine can be divided into four groups and prepared for intravenous infusion sequentially; compound amino ...

Embodiment 3

[0085] Embodiment 3: Preparation example of pharmaceutical composition

[0086] A pharmaceutical composition, its component is:

[0087] Compound amino acid: containing 4.40g of isoleucine, 6.80g of leucine, 5.30g of lysine acetate, 0.60g of methionine, 0.80g of phenylalanine, 2.30g of threonine, and 0.75g of tryptophan g, valine 5.30g, arginine 4.40g, histidine 2.35g, glycine 3.15g, alanine 4.15g, proline 3.55g, aspartic acid 1.25g, asparagine 0.27g, N-acetyl-L-cysteine ​​0.40g, glutamic acid 2.85g, ornithine hydrochloride 0.83g, serine 1.85g, N-acetyl-L-tyrosine 0.43g, mixed into 500ml liquid;

[0088] Vitamins: Vitamin B 6 Add 3-5g and 2g of vitamin C to 250ml 0.9% sodium chloride injection;

[0089] Calcium gluconate: 10ml of 10% calcium gluconate was added to 50ml of 0.9% sodium chloride injection;

[0090] Rocephine (ceftriaxone sodium for injection): Rocephine 2g was added to 100ml 0.9% sodium chloride injection;

[0091] Compound amino acids, vitamins, calcium gl...

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Abstract

The invention belongs to the field of pharmacy, and discloses a pharmaceutical composition for treating stubborn acne and application thereof. The pharmaceutical composition is mainly prepared from compound amino acid, vitamins and calcium gluconate, and in necessity, a therapeutically effective amount of antibiotics can be added. According to the main pathogenesis of the stubborn acne, targeted collaborative treatment is conducted, the metabolic activity of the human life can be quickly activated, and endocrine dyscrasia and hormone metabolism disorders are quickly corrected. The pharmaceutical composition has the effects of diminishing inflammation, reducing exudation, resisting angioneurotic edema, resisting allergy and the like, the functions of body's enzyme metabolism, diuresis, detoxification and brain and nervous system protection are promoted, the nutriture and the immunity function of a body are improved, disease alleviation and recovery of a patient suffering from the stubborn acne are facilitated, and the pharmaceutical composition is suitable for clinical popularization.

Description

technical field [0001] The invention belongs to the field of pharmacy and relates to a pharmaceutical composition for treating intractable acne and its application. Background technique [0002] 1. Intractable acne is a disease that is particularly prone to repeated attacks. It is very difficult to cure this disease: intractable acne is a skin disease that is prone to occur in the human body, and it is a particularly easy It is very difficult to cure the disease that recurs repeatedly. Acne, also known as acne, pimples, pimples, pimples, acne, etc., is a chronic inflammation of the pilosebaceous glands caused by embolism and sebum excretion disorders caused by hyperkeratosis of the skin. It usually occurs on the face, chest and back, often with blackheads The pathogenesis of acne, papulopustular nodules, cysts and other manifestations is not very clear, and some patients have relapsed for more than 9 years, which is very painful. [0003] Intractable acne is generally caus...

Claims

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Application Information

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IPC IPC(8): A61K33/06A61K31/4415A61K31/546A61K31/198A61K31/401A61K31/405A61K31/4172A61K31/375A61K31/191A61K9/08A61P17/10
CPCA61K31/198A61K31/401A61K31/405A61K31/4172A61K31/4415A61K31/375A61K31/191A61K33/06A61K31/546A61K9/0019A61K9/08A61P17/10A61K2300/00
Inventor 岳茂兴
Owner 岳茂兴
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