Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Extraction method and purification method of acorus gramineus volatile oil

The technology of an extraction method and a purification method is applied in the field of extraction and purification of the volatile oil of Acorus calamus, can solve the problems of low extraction efficiency, high technical requirements, damage to the chemical substance structure of the volatile oil, etc., achieves mild extraction conditions, is suitable for popularization and application, and improves the The effect of extraction efficiency

Active Publication Date: 2019-10-08
SHANXI UNIV OF CHINESE MEDICINE
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, many researchers have carried out in-depth research on the pharmacognosy and chemical components of Shichangpu, but the corresponding production process reports are few and rough. According to many research results, there is no optimal extraction method for the volatile oil of Shichangpu. and suitable for promotion
[0004] The commonly used volatile oil extraction methods are steam distillation and supercritical CO 2 Extraction method, etc., steam distillation method has long extraction time, low extraction efficiency, high extraction temperature, easy to destroy active ingredients, low yield of extracted volatile oil and many impurities; while supercritical CO 2 Although the extraction method has the advantages of relatively thorough separation and no solvent residue, this method has high technical requirements and a large investment in equipment costs. It is difficult to balance the cost for extracting volatile oils. The extracted volatile oils are expensive and are not suitable for industrialization. In addition, Carbon dioxide is an acidic gas, and it may also destroy the structure of chemical substances in the volatile oil during the extraction process

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Extraction method and purification method of acorus gramineus volatile oil
  • Extraction method and purification method of acorus gramineus volatile oil
  • Extraction method and purification method of acorus gramineus volatile oil

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0143] Embodiment 1 (preferred embodiment):

[0144] A method for extracting volatile oil of Acorus calamus, said extraction method comprising the following steps:

[0145] ①Pretreatment: take 20.000g of Shichangpu traditional Chinese medicine decoction pieces, dry, pulverize, and pass through a 30-mesh sieve to obtain Shichangpu powder;

[0146] ②Ultrasonic extraction: Put the calamus powder in step ① into a round-bottomed flask, add petroleum ether at a material-liquid ratio of 1:12.5 (g / ml), then put the round-bottomed flask into an ultrasonic cleaning machine for ultrasonic extraction , the ultrasonic power is 182W, the ultrasonic extraction time is 37min, the ultrasonic extraction temperature is 30°C, and a reflux condenser is installed on the neck of the round bottom flask to condense and recover the extract;

[0147] ③Decompression suction filtration: Transfer the extract obtained in step ② into a Buchner funnel for circulating water vacuum decompression suction filtra...

Embodiment 2

[0155] A method for extracting volatile oil of Acorus calamus, said extraction method comprising the following steps:

[0156] ①Pretreatment: take 20.000g of Shichangpu traditional Chinese medicine decoction pieces, dry, pulverize, and pass through a 30-mesh sieve to obtain Shichangpu powder;

[0157] ②Ultrasonic extraction: Put the calamus powder in step ① into a round-bottomed flask, add petroleum ether at a material-liquid ratio of 1:24 (g / ml), then put the round-bottomed flask into an ultrasonic cleaning machine for ultrasonic extraction , the ultrasonic power is 100W, the ultrasonic extraction time is 50min, the ultrasonic extraction temperature is 50°C, and a reflux condenser is installed on the neck of the round bottom flask to condense and recover the extract;

[0158] ③Decompression suction filtration: Transfer the extract obtained in step ② into a Buchner funnel for circulating water vacuum decompression suction filtration. After the residue at the bottom of the roun...

Embodiment 3

[0166] A method for extracting volatile oil of Acorus calamus, said extraction method comprising the following steps:

[0167] ①Pretreatment: take 20.000g of Shichangpu traditional Chinese medicine decoction pieces, dry, pulverize, and pass through a 30-mesh sieve to obtain Shichangpu powder;

[0168] ②Ultrasonic extraction: Put the calamus powder in step ① into a round-bottomed flask, add petroleum ether at a material-to-liquid ratio of 1:8 (g / ml), then put the round-bottomed flask into an ultrasonic cleaning machine for ultrasonic extraction , the ultrasonic power is 250W, the ultrasonic extraction time is 24min, the ultrasonic extraction temperature is 25°C, and a reflux condenser is installed on the neck of the round bottom flask to condense and recover the extract;

[0169] ③Decompression suction filtration: Transfer the extract obtained in step ② into a Buchner funnel for circulating water vacuum decompression suction filtration. After the residue at the bottom of the ro...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of traditional Chinese medicine extraction, and discloses an extraction method and a purification method of acorus gramineus volatile oil. The extraction method of the acorus gramineus volatile oil includes the steps of pre-treatment, ultrasonic extraction, vacuum suction filtration, rotary evaporation and other steps; and the purification method of theacorus gramineus volatile oil is to obtain the high-purity refined acorus gramineus volatile oil through ethanol immersion, vacuum and suction filtration and rotary evaporation carrying on the acorusgramineus volatile oil. The extraction method of the acorus gramineus volatile oil is reasonable in design and simple in technology, an ultrasonic extraction method is adopted, the extraction methodhas the advantages of being short in extraction time, mild in extraction conditions, high in product yield, high in active ingredient content of the obtained acorus gramineus volatile oil, no residualin solvent extraction, energy saving and environmental protection, and the purification method of the acorus gramineus volatile oil has the advantages of being simple in operation, high in purification efficiency, high in product active ingredient content and no residual in solvent.

Description

technical field [0001] The invention relates to the technical field of extraction of traditional Chinese medicines, in particular to a method for extracting and purifying volatile oil of Acorus calamus. Background technique [0002] Shichangpu is the dry rhizome of the perennial herbaceous plant Shichangpu in the family Araceae. It tastes pungent and bitter. Stroke aphasia embolism. At present, in clinical practice, Shichangpu is widely used in the treatment of diseases related to central nervous system and cardiovascular and cerebrovascular diseases. [0003] The main medicinal ingredient of Shichangpu is volatile oil, and the main component of volatile oil is asarone. At present, it is generally believed that the volatile oil of Shichangpu has a two-way regulating effect on the central nervous system, which not only calms the nerves (sedation, anti-convulsion), but also refreshes the mind (excitement, anti-depression). In recent years, many researchers have carried out ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/888C11B9/02A61K125/00
CPCA61K36/888A61K2236/15A61K2236/35C11B9/025
Inventor 杨丽霞冯婷婷王堃
Owner SHANXI UNIV OF CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com