Acne gel, preparation method thereof and application of acne gel

A technology of gel and acne, applied in acne gel and its preparation process and application field, can solve the problems of secondary skin damage, ineffective cure, prone to side effects, etc., achieve faster release speed, suitable for promotion , the effect is obvious

Inactive Publication Date: 2019-09-06
GANSU UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the main treatment methods are topical drugs such as vitamin A acids, oral antibiotics such as tetracyclines, oral isotretinoin, anti-androgen therapy and oral glucocorticoids, etc., but the use of the above drugs is prone to side effects and the effect is not good. Ideal, it is easy to relapse after stopping the drug, and it will cause secondary damage to the skin, which cannot be effectively cured

Method used

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  • Acne gel, preparation method thereof and application of acne gel
  • Acne gel, preparation method thereof and application of acne gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The formula of an acne gel is: Scutellaria baicalensis 5g, Coptidis 5g, Phellodendron 5g, Sophora flavescens 5g, Angelica dahurica 5g, Baiji 15g, Poria cocos 5g, Salvia miltiorrhiza 15g, urea 15g, salicylic acid 1g, Carbomer 940 25g, Laurazone 5g, triacetamide amount.

Embodiment 2

[0019] The formula of an acne gel is: Scutellaria baicalensis 15g, Coptidis 15g, Cortex Phellodendri 15g, Sophora flavescens 15g, Angelica dahurica 15g, Baiji 5g, Poria cocos 5g, Salvia miltiorrhiza 5g, urea 15g, salicylic acid 6g, Carbomer 940 15g, Laurazone 15g, appropriate amount of triacetamide.

Embodiment 3

[0021] The formula of an acne gel is: Scutellaria baicalensis 10g, Coptidis 10g, Phellodendron 10g, Sophora flavescens 10g, Angelica dahurica 10g, Baiji 10g, Poria cocos 10g, Salvia miltiorrhiza 10g, urea 10g, salicylic acid 3g, Carbomer 940 20g, Laurocapram 3% is 10g, and triacetamide is an appropriate amount.

[0022] Carbomer 940 with a specific amount of compatibility with other components is used as the matrix, and laurocapram transdermal penetration enhancer increases the coupling effect between the gel and the skin, greatly shortens the time for drug transdermal absorption, and accelerates the drug release rate Absorbed through local transdermal administration, the drug is absorbed quickly, the medicinal ingredients directly reach the affected area, the local drug concentration is high, and there is no toxic side effect such as gastrointestinal reactions; the present invention is a gel dosage form, which improves the antipruritic effect and prolongs the shelf life ;In a...

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Abstract

The invention discloses an acne gel, a preparation method thereof and an application of the acne gel. The acne gel comprises, by weight, 5-15 parts of Baikal skullcap roots, 5-15 parts of Chinese goldthread rhizomes, 5-15 parts of amur corktree barks, 5-15 parts of lightyellow sophora roots, 5-15 parts of dahurian angelica roots, 5-15 parts of common bletilla tubers, 5-15 parts of Indian breads, 5-15 parts of red-rooted salvia roots, 5-15 parts of urea, 1-6 parts of salicylic acid, 15 -25 parts of Carbomer 940, 5-15 parts of laurocapram and an appropriate amount of triacetamide. The acne gel is rigorous in formula and reasonable in demonstration and conforms to the formula principles of 'monarch, minister, assistant and guide', and the synergistic effects among various drugs are achieved.The acne gel can treat surgical surface infections such as various acnes, large carbuncle pyogenic infections, scald and fire burn and is obvious in swelling diminishing and anti-inflammation effect,good in spreadability, well received by the majority of patients and suitable for popularization, and medicinal materials are low in cost and easily acquired.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to an acne gel and its preparation process and application. Background technique [0002] Acne is a chronic inflammatory skin disease that mainly occurs in the pilosebaceous glands of human skin. It is mainly caused by excessive sebum secretion, blockage of pilosebaceous gland ducts, bacterial infection, and inflammatory reactions. The clinical manifestations are mainly acne and papules on the face. It is characterized by pleomorphic skin lesions such as pustules and nodules. At present, the main treatment methods are topical drugs such as vitamin A acids, oral antibiotics such as tetracyclines, oral isotretinoin, anti-androgen therapy and oral glucocorticoids, etc., but the use of the above drugs is prone to side effects and the effect is not good. Ideal, it is easy to relapse after stopping the drug, and it will cause secondary damage...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/06A61K47/22A61K47/32A61P17/10A61P17/02A61P17/00A61P29/00A61P31/00A61K31/17A61K31/60
CPCA61K9/0014A61K9/06A61K31/17A61K31/60A61K36/076A61K36/232A61K36/489A61K36/537A61K36/539A61K36/718A61K36/756A61K36/898A61K47/22A61K47/32A61P17/00A61P17/02A61P17/10A61P29/00A61P31/00A61K2300/00
Inventor 王思农
Owner GANSU UNIV OF CHINESE MEDICINE
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