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Biocompatible microphone and preparation method thereof

A microphone and sound bridge technology, applied in the field of biomedical engineering, to achieve the effect of long vibration attenuation, good sealing and long vibration attenuation

Inactive Publication Date: 2019-08-23
EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 1. How to improve the coupling method of the piezoelectric sensor? The previous experiments were all glue adhesion coupling, and the glue was non-biocompatible industrial glue; 2. How to improve the piezoelectric sensor to improve its stability and biocompatibility? At present, piezoelectric sensors are all made by manual welding. For further clinical and long-term application, they must have stability and biocompatibility.

Method used

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  • Biocompatible microphone and preparation method thereof
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  • Biocompatible microphone and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1 Preparation of a biocompatible piezoelectric ceramic microphone with an acoustic bridge clip structure

[0040] Such as Figure 1~3 as shown,

[0041] 1. Titanium shell production: The titanium shell is a tubular structure with a length of 5.91mm, a rear diameter of 2.02mm, a front diameter of 2.4mm, and a weight of about 40mg. The sound bridge clip is laser welded, which is an extremely thin titanium metal clip with a diameter of 1.38mm. Attaches to the long process of the incus near the stapes;

[0042] 2. Internal connection: Paste and fix the LMV1032 preamplifier system on one end of the piezoelectric ceramic bichip (length 4.0mm) with biological glue;

[0043] Conductive epoxy resin (EPOXY) connects the platinum wire to the terminal of the preamplifier. (The curing temperature of the conductive epoxy resin is ~100°C to 140°C). Two of the platinum wires are directly connected to the terminal, and the remaining two are of appropriate length. A platinum w...

Embodiment 2

[0045] Example 2 In vitro test experiment

[0046] 1) Experimental equipment RIGOL signal generator, Lenovo notebook computer, YJ56 dual-channel DC power supply, IBM speaker, smart sensor AR814 sound level meter, wire clamp, new piezoelectric microphone (NFPM). All experiments are carried out in a quiet soundproof box (background noise ≤ 30dB SPL);

[0047] 2. In the in vitro experiment, the signal generator outputs the acoustic signal to the speaker, and the new piezoelectric microphone picks up the acoustic signal, converts it into an electrical signal, passes through the NI DAQ9162 data acquisition card, outputs it to the recording computer, and uses NI Lab VIEW SignalExpress software to record it for analysis Calculate and compare the amplitude of the frequency response main peak and the frequency response curve of each group;

[0048] 3. The standard test sound emitted by the signal generator in vitro is output through the above-mentioned high-fidelity speaker as the sou...

Embodiment 3

[0055] Example 3 In vivo (fresh temporal bone) experiment of NFPM

[0056] 1. Experimental equipment: ELAC speaker, MARANTZ power amplifier, RIGOL signal generator, AR814 sound level meter, YJ56 dual-channel DC power supply, ear microsurgical instruments and microscope, all experiments are carried out in a quiet soundproof box ( Background noise ≤20 dB SPL);

[0057] 2. Temporal bone: 3 sets of fresh temporal bone specimens, 5 ears in total (2 left ear, 3 right ear), all donated by the Shanghai Red Cross Society, all donated specimens have a body donation certificate;

[0058] 3. Test method: ① Tympanoplasty was performed through a retroauricular incision, and the operation method was a posterior tympanic approach to expose the long process of the incus and the anvil-stirrup joint. The integrity of the bone wall and skin of the external auditory canal is preserved (complete wall type), and all ligaments of the ossicular chain are preserved during the operation, so as to ensur...

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Abstract

The invention belongs to the technical field of biomedical engineering, and relates to a micro-microphone which can be implanted into a middle ear, in particular to a biocompatible piezoelectric ceramic microphone with a sound bridge clamp structure and a preparation method thereof. The micro piezoelectric ceramic implanted microphone of the present invention comprises a strip-shaped thin piezoelectric ceramic bimorph with a length of 2.0 to 6.0 mm, a width of 1.0 to 2.0 mm, a thickness of 0.3 mm, and a piece of LMV1032 preamplifier, a metal square cylindrical copper shell having an outer dimension of 3.0 to 7.0 mm x 1.6 mm to 3.0 mm x 1.3 mm and an inner diameter of 1.3 mm x 1.1 mm, and is prepared in combination with MEMS technology. The implantable piezoelectric ceramic microphone designed and manufactured by the invention can be completely implanted into a human body in a manner of directly coupling and fixing the implantable piezoelectric ceramic microphone to a hammer bone, and has relatively high sensitivity and relatively good frequency response characteristic for a pure sound signal test of 100Hz-20000Hz. Experiments prove that the external microphone can be replaced to transmit and convert sound signals.

Description

technical field [0001] The invention belongs to the technical field of biomedical engineering and relates to a miniature microphone which can be implanted in the middle ear, in particular to a biocompatible piezoelectric ceramic microphone with an acoustic bridge clip structure and a preparation method thereof. Background technique [0002] The prior art discloses that a cochlear implant is a medical device that utilizes functional electrical stimulation (functional electrical stimulation) to directly excite residual spiral nerve cells to restore hearing to patients with extremely severe or severe sensorineural deafness. Cochlear implants currently in clinical use are mainly composed of external parts (microphone, battery, speech processor, transmitting coil) and internal implanted parts (receiving coil / stimulator, electrodes). In clinical practice, the above-mentioned cochlear implants are all partially implanted, that is, microphones, signal amplifiers, voice processors, a...

Claims

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Application Information

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IPC IPC(8): H04R17/02H04R31/00
CPCH04R17/02H04R31/006
Inventor 迟放鲁高娜贾贤浩吴拥真许信达
Owner EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
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