Radix codonopsis extract and preparing method and application thereof

A technology of extract and Codonopsis pilosula, applied in the field of Codonopsis pilosula extract and its preparation, can solve the problems of low enzymatic hydrolysis efficiency of amylase, insufficient enzymatic hydrolysis of Codonopsis pilosula cell wall, and insufficient release of active substances such as polysaccharides, so as to ensure food safety properties, the high content of Codonopsis polysaccharides, and the effect of improving extraction efficiency

Inactive Publication Date: 2019-08-23
CHONGQING ACADEMY OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above scheme has the problems of low enzymatic hydrolysis efficiency of amylase, insufficient enzymolysis of the cell wall of Codonopsis pilosula, and insufficient release of active substances such as polysaccharides in Codonopsis pilosula cells.

Method used

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  • Radix codonopsis extract and preparing method and application thereof
  • Radix codonopsis extract and preparing method and application thereof
  • Radix codonopsis extract and preparing method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0046] Experimental Example 1 is to detect the impact of lysine and sodium alginate on the activity of β-glucosidase by filter paper enzyme activity (FPA) assay;

experiment example 2

[0047] Experimental example 2 is to determine the enzymatic hydrolysis efficiency under the synergistic action of lysine, sodium alginate and β-glucosidase.

Embodiment 1

[0048] Embodiment 1: Utilize the technical solution of the present invention to prepare Codonopsis pilosula extract

[0049] (1) Preparation of activator: mix lysine (purity 99%, Shanghai Sangong) and sodium alginate (purity 99%, Shanghai Sangong) according to the mass ratio of 1:4 and grind for 10 minutes to fully mix, pass 80 mesh sieve to obtain a solid dispersion. Add deionized water to dissolve the solid dispersion of lysine-sodium alginate, and make the final concentration of sodium alginate 0.8% by weight and 0.2% by weight of lysine. Stir at room temperature for 15 minutes to make it a uniform system. Stand for defoaming treatment for 2 hours to obtain the activator. The storage condition of the activator is 4°C, protected from light, and used within 24 hours after the preparation is completed.

[0050] (2) Pretreatment of Codonopsis pilosula: Take 50g of fresh Codonopsis pilosula (that is, Codonopsis pilosula), wash it, drain it, cut it into 1-2cm size, put it in a ...

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Abstract

The invention relates to the field of biomedicines, and relates to a radix codonopsis extract and a preparing method and application thereof. When the radix codonopsis extract is prepared, beta-glucosidase and an activating agent are added to a radix codonopsis water extraction system, and the activating agent contains lysine and sodium alginate. According to the technical scheme, radix codonopsiscell walls are degraded through an enzymolysis method, the enzymolysis effect is enhanced through the enzyme activating agent, the release amount of active materials in radix codonopsis cells is increased, and the preparing efficiency of the radix codonopsis extract is increased. According to the scheme, the radix codonopsis extract can be applied to practices such as the extraction of radix codonopsis active components and the preparation, research and development of radix codonopsis healthcare products, cosmetics and medicines.

Description

technical field [0001] The invention relates to the field of biomedicine, relates to a traditional Chinese medicine extract and its preparation method and application, in particular to a Codonopsis pilosula extract and its preparation method and application. Background technique [0002] Radix codonopsis (radix codonopsis) is a traditional precious Chinese herbal medicine in my country. "Chinese Pharmacopoeia" records that Radix Codonopsis is sweet and flat in nature, and belongs to the spleen and lung meridian. The functional components of Codonopsis pilosula are mainly polysaccharides and saponins. The functions of Codonopsis polysaccharides are mainly to enhance immunity, assist in improving memory, relieve physical fatigue, improve nutritional anemia, and assist protection against gastric mucosal damage. The functions of Codonopsis saponins are mainly to assist in lowering blood lipids, assisting in lowering blood pressure, improving hypoxia tolerance, and improving nut...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/344A61K31/715A61K47/18A61K47/36A61P39/06A61P3/06A61K8/9789A61K8/73A61Q19/08A23L33/125A61K125/00
CPCA23V2002/00A61K8/73A61K31/715A61K36/344A61K47/183A61K47/36A61K2236/19A61K2236/331A61Q19/08A23L33/125A61K8/9789A61P3/06A61P39/06A23V2200/30A23V2250/51
Inventor 王玉李滨秦建波程鹏
Owner CHONGQING ACADEMY OF SCI & TECH
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