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Single-pole nano knife treatment unit

A treatment device and nano-knife technology, which is applied in medical science, surgery, surgical instrument parts, etc., can solve the problems of difficult and long-time nano-knife cloth needles, and achieve shortening ablation treatment time, reducing trauma, and ablation time short effect

Inactive Publication Date: 2019-08-16
ANHUI SHAOSHI HUAAI BIOLOGICAL MEDICAL ELECTRONICS TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of this, the purpose of the present invention is to propose a monopolar nano-knife treatment device, to overcome the difficulty of nano-knife cloth needles in the prior art and take a long time

Method used

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Embodiment Construction

[0020] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be described in further detail below in conjunction with specific embodiments and with reference to the accompanying drawings.

[0021] It should be noted that all expressions using "first" and "second" in the embodiments of the present invention are to distinguish two entities with the same name but different parameters or parameters that are not the same, see "first" and "second" It is only for the convenience of expression, and should not be construed as a limitation on the embodiments of the present invention, which will not be described one by one in the subsequent embodiments.

[0022] Tumor ablation therapy technology refers to the extremely precise puncture of radio frequency, microwave, freezing, laser, electric field and other energies to the tumor target area under the guidance of images, and implements precise minimally invasive ablation...

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Abstract

The invention discloses a single-pole nano knife treatment unit. Through arranging a single ablation electrode, a plurality of neutral electrodes and a pulse generator, adopting the field energy and using irreversible electroporation, the purpose of tissue ablation is realized, through applying a high-strength external electric field to make a cell membrane be permanently transparent and destroy the steady state in a cell, the ablation time is short without being influenced by blood flow, so that complete cell death can be generated around a blood vessel; since living cells are ablated, cell matrix and cell surrounding structure can be retained, and the structures and functions of great vessels and bile ducts remain complete. According to the single-pole nano knife treatment unit, the single ablation electrode is arranged, so that the puncture difficulty is reduced, the trauma of a patient is also reduced; the plurality of neutral electrodes are used for adjusting electric field distribution, so as to provide a return loop for current; the pulse generator is arranged to apply an electric field intensity which exceeds a threshold value between the ablation electrode and the neutralelectrodes, so that the volume of single ablation can be increased, the ablation frequency is reduced, and the ablation treatment time is further shortened.

Description

technical field [0001] The invention relates to the technical field of tumor tissue ablation, in particular to a unipolar nano-knife treatment device. Background technique [0002] Nanoknife ablation is a non-thermal ablation technique that uses irreversible electroporation to achieve tissue ablation. Irreversible electroporation refers to the process of permanently permeabilizing cell membranes by applying a high-intensity external electric field. The transmembrane potential induced by an external electric field leads to the formation of countless nanoscale pores in the cell membrane, which disrupts the homeostasis of the cell. If the applied electric field exceeds a certain threshold, it will cause permanent damage to the cell membrane structure and the homeostasis of the cell, causing an immune response, leading to cell apoptosis. [0003] The multipolar nanoknife tumor ablation device needs multi-electrode needles to puncture into the tumor in parallel to increase the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/00
CPCA61B18/00A61B2018/00577A61B2018/00613A61B2018/00964
Inventor 邵西良
Owner ANHUI SHAOSHI HUAAI BIOLOGICAL MEDICAL ELECTRONICS TECH CO LTD
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