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Nasal influenza vaccine composition

A technology of influenza vaccine and composition, applied in the direction of drug combination, microorganism, drug delivery, etc., to achieve the effects of small side effects, long-term distribution, and induction of immune response

Inactive Publication Date: 2019-07-23
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NAT INST OF INFECT IOUS DISEASES +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] As mentioned above, it is urgently desired to develop and put into practical use a nasal administration type vaccine as a next-generation influenza vaccine based on existing influenza vaccines administered subcutaneously or intramuscularly. There are various problems in the face of practical application, such as the toxicity of the adjuvant

Method used

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  • Nasal influenza vaccine composition
  • Nasal influenza vaccine composition
  • Nasal influenza vaccine composition

Examples

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Embodiment 1

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Embodiment 2

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Embodiment 3

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Abstract

The present invention relates to a nasal mucosal spray delivery type influenza vaccine composition which is characterized in that the composition comprises a gel base including an influenza virus inactivated whole particle antigen and a carboxyl vinyl polymer but does not comprise an adjuvant.

Description

[0001] This application is a divisional application of the original application of the PCT international application PCT / JP2013 / 078721 with the international filing date of October 23, 2013, which entered the Chinese national phase with the application number 201380068031.4 and the invention name "nasal influenza vaccine composition" . technical field [0002] The invention relates to a nasal mucosa spray administration type influenza vaccine composition. Background technique [0003] Influenza is an acute respiratory infectious disease caused by influenza virus, especially in winter, which is prevalent every year. In addition, sometimes it becomes a worldwide pandemic, and there are many cases where the disease becomes severe and leads to death. Influenza is known to have a certain preventive effect through influenza vaccination, and the vaccination is widely performed before the epidemic period. [0004] In Japan, influenza vaccines are approved only for subcutaneous adm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/145A61K9/06A61K47/32A61P31/16
CPCA61K9/06A61K47/32A61K9/0043A61K2039/543C12N2760/16134A61K2039/5252A61K2039/55555C12N2760/16234A61K39/12A61K39/145A61P31/00A61P31/16A61P37/04A61K47/30C12N7/00C12N2760/16121
Inventor 长谷川秀树铃木忠树相内章上下泰造宫崎隆
Owner JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NAT INST OF INFECT IOUS DISEASES
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