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Preparing method of mixed concentrated platelets

A platelet and platelet-rich technology, which is applied in the field of medical blood transfusion, can solve the problems of inconvenient promotion, aggravating the circulation pressure of transfusion patients, and low volume of mixed concentrated platelets, so as to achieve the effect of low volume and saving blood resources

Active Publication Date: 2019-06-14
西安市中心血站(陕西省血液中心)
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Problems solved by technology

[0003] The present invention provides a preparation method of mixed concentrated platelets, which is used to solve the problem in the prior art that the capacity of mixed concentrated platelets is much larger than the treatment volume of apheresis platelets, which is not easy to popularize and will also increase the circulation pressure of transfusion patients problem, achieved the technical effect of low volume of mixed concentrated platelets, and the platelet count can meet the requirements of use, saving blood resources

Method used

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  • Preparing method of mixed concentrated platelets

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Embodiment

[0022] figure 1 It is a preparation method of mixed concentrated platelets in the embodiment of the present invention, such as figure 1 As shown, the method includes:

[0023] Step 1: Obtain the collected whole blood of the first preset volume.

[0024] Specifically, the collected whole blood is the blood of the blood donors at the voluntary blood donation sites, and the blood donors who can collect blood are all in good health, that is to say, the physical condition of the collectors must meet the health indicators, that is, meet the GB18467-2011 "Health Examination Standards for Blood Donors". For example, whole blood with a capacity of 390-410ml can be collected through a five-unit blood collection bag, stored and transported at room temperature, and sent to the component department for further processing within 6 hours after blood collection.

[0025] Step 2: According to the first preset condition, the whole blood is centrifuged with a centrifuge, wherein the whole blo...

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Abstract

The invention discloses a preparing method of mixed concentrated platelets, and belongs to the technical field of medical transfusion. The preparing method comprises the steps of obtaining collected whole blood with a first preset capacity; adopting a centrifugal machine for centrifuging the whole blood under a first preset condition; adopting a blood composition separator for separating plasma layers in the centrifuged whole blood into platelet-poor plasma layers and platelet-rich plasma layers; adopting the blood composition separator for separating albuginea layers in the centrifuged wholeblood; adopting the blood composition separator for transferring platelet-rich plasma into an albuginea layer bag, and obtaining platelet-rich albuginea; putting the platelet-rich albuginea at a preset temperature for storage; repeating the steps above, and obtaining multiple parts of the platelet-rich albuginea with the same blood type; under a second preset condition, obtaining concentrated platelets after centrifugation, and collecting the platelets of the same blood type into a platelet storage blood bag to obtain the mixed concentrated platelets. The preparing method has the technical advantages that the capacity of the mixed concentrated platelets is low, the platelet count can meet the using requirement, and the blood resource is saved.

Description

technical field [0001] The invention relates to the technical field of medical blood transfusion, in particular to a preparation method of mixed concentrated platelets. Background technique [0002] The professional term for platelets separated from whole blood is called concentrated platelets. Generally, 200ml whole blood can separate 1U concentrated platelets, and the PLT is 2×10 10 / bag, and the treatment volume of a patient's infusion is about 10-12U. The traditional process not only has cumbersome preparation process, low platelet recovery rate, but also inconvenient clinical transfusion. There are two conventional methods for preparing mixed platelet concentrates. One is to collect 5-7 bags of concentrated platelets into special platelet storage bags by aseptic splicing to make mixed platelet concentrates. This method is consistent with the terms and definitions in GB18469-2012 "Quality Requirements for Whole Blood and Blood Components"; the other is to pool 5-7 bag...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/02A61K35/19
Inventor 张雅莉
Owner 西安市中心血站(陕西省血液中心)
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