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Lotion containing natural astaxanthin ester and preparation method thereof

An astaxanthin ester, natural technology, applied in the field of emulsion containing natural astaxanthin ester and preparation thereof, can solve the problems of high operating temperature, unsuitable for industrialized large-scale application, etc., achieves low water content and improves storage stability The effect of improving the absorption rate of living body

Active Publication Date: 2019-05-31
睿藻生物科技(苏州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The Chinese invention patent with application number 201410578096.X filed on October 24, 2014 also provides a method for making astaxanthin emulsion, but this method requires a high operating temperature and operates in a nitrogen environment , so it is not suitable for industrialized large-scale application, the water content of the emulsion prepared by this method is as high as more than 90%, and its astaxanthin content is only 0.1% of the total mass of the emulsion, and the astaxanthin emulsion prepared by this method The average particle size is greater than 170nm

Method used

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  • Lotion containing natural astaxanthin ester and preparation method thereof
  • Lotion containing natural astaxanthin ester and preparation method thereof
  • Lotion containing natural astaxanthin ester and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035]Mix 30g of corn oil and 30g of glycerin and heat to 50°C, dissolve 4g of Haematococcus pluvialis extract (ie, astaxanthin ester) (astaxanthin ester) which is 33.2% astaxanthin based on free astaxanthin, and add And 3 g of polyglyceryl-10 laurate, 5 g of soybean lecithin, 0.5 g of tocopherol, and 0.5 g of sorbitol laurate were dissolved to form an oil phase. 5 g of sucrose laurate, 2 g of sorbitol were dissolved in 20 g of water to form an aqueous phase. Mix the oil phase with the water phase, first use a high-speed shear emulsifier (Wiggens, D-500, China) to make the mixture into a coarse emulsion, and then use a high-pressure homogenizer (ATS, AH-NANO, China) to make a finished product lotion.

[0036] After testing, the emulsion astaxanthin accounts for 1.3% by weight. The average particle size of the emulsion prepared by this method is 86nm (as attached figure 1 shown), after sealed storage at 50 degrees Celsius for 30 days, the degradation rate of astaxanthin (cal...

Embodiment 2

[0038] After mixing 20g safflower oil with 40g glycerin, heat it to 45°C, dissolve 9g (astaxanthin content of 33.2% based on free astaxanthin) Haematococcus pluvialis extract (ie astaxanthin ester), successively Add and dissolve 3g polyglyceryl-10 laurate, 5g soybean lecithin, 0.5g sorbitan laurate to form an oil phase. 5 g of sucrose laurate, 2 g of sorbitol, 0.5 g of sodium ascorbate were dissolved in 15 g of water to form an aqueous phase. Mix the oil phase with the water phase, first use a high-speed shear emulsifier (Wiggens, D-500, China) to make the mixture into a coarse emulsion, and then use a high-pressure homogenizer (ATS, AH-NANO, China) to make a finished product lotion.

[0039] After testing, the emulsion astaxanthin accounts for 2.8% of the total weight. The average particle size of the emulsion prepared by this method is 101nm (as attached figure 1 shown), after sealed storage at 50°C for 30 days, the degradation rate of astaxanthin (calculated as free asta...

Embodiment 3

[0041] Mix 15g of olive oil with 40g of glycerin and heat to 50°C, dissolve 9g of Haematococcus pluvialis extract (ie, astaxanthin ester) (astaxanthin ester) which is 33.2% astaxanthin based on free astaxanthin, and add And 3 g of polyglyceryl-10 laurate, 10 g of soybean lecithin, 0.5 g of sorbitol laurate were dissolved to form an oil phase. 5 g of sucrose palmitate, 2 g of sorbitol, 0.5 g of sodium ascorbate were dissolved in 15 g of water to form an aqueous phase. Mix the oil phase with the water phase, first use a high-speed shear emulsifier (Wiggens, D-500, China) to make the mixture into a coarse emulsion, and then use a high-pressure homogenizer (ATS, AH-NANO, China) to make a finished product lotion.

[0042] After testing, the emulsion astaxanthin accounts for 2.7% of the total weight. The average particle size of the emulsion prepared by this method is 93nm (as attached figure 1 shown), after sealed storage at 50°C for 30 days, the degradation rate of astaxanthin ...

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Abstract

The invention discloses a lotion containing natural astaxanthin ester. The lotion is prepared from natural astaxanthin ester, fat, oil, phospholipid, polyalcohols, sucrose ester, polyalcohol aliphaticester, a stabilizer and water. The lotion is low in water content. Under the condition that no chemical processing is performed on the natural astaxanthin ester, the storage stability of the naturalastaxanthin ester is remarkably improved, meanwhile, liquid drops with the average grain size being 100 nanometers are dispersed into water to form a transparent water solution, and meanwhile the natural astaxanthin ester living body absorption rate is remarkably increased. The lotion can be applied to food, beverages, cosmetics, skincare products, medicine and other products.

Description

technical field [0001] The invention belongs to the technical field of biological material preparation, in particular to an emulsion containing natural astaxanthin ester and a preparation method thereof. Background technique [0002] Natural astaxanthin is the strongest antioxidant currently known and can be used as a new type of active factor in food, beverages, cosmetics, skin care products, and medicines. Therefore, natural astaxanthin has huge market potential. Natural astaxanthin mainly exists in the form of astaxanthin ester, which is an oil-soluble substance with extremely poor water solubility. At the same time, as an antioxidant, untreated astaxanthin ester is easily oxidized under natural conditions degrade and lose activity. Through chemical methods, astaxanthin esters can be converted into water-soluble free astaxanthin, which can improve the water solubility of astaxanthin, but it cannot improve the storage stability of astaxanthin. Chemical residues are left...

Claims

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Application Information

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IPC IPC(8): A61K8/37A61K8/06A61K31/225A61K9/107A61Q19/00A23D7/04A23L2/38A23L2/52A23L33/10
Inventor 李彤徐耀刚吕朕晨
Owner 睿藻生物科技(苏州)有限公司
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