Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medical degradable zinc-based composite material and preparation method and application thereof

A composite material and zinc-based technology, applied in medical science, surgery, etc., can solve the problems of difficult cleaning, too fast corrosion of magnesium alloy, slow corrosion of zinc alloy, etc., and achieve the effect of moderate degradation speed

Active Publication Date: 2019-05-24
湖南华翔医疗科技有限公司
View PDF8 Cites 26 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The degradation products of pure magnesium and magnesium-based alloys are non-toxic and degradable, but their corrosion resistance is very poor, and they will be degraded soon in the human body, unable to provide sufficient mechanical support time
Existing alloy degradable materials mix zinc and other metals together through smelting, but the existing magnesium alloys of this type corrode too fast and zinc alloys corrode too slowly, which cannot meet the needs of orthopedic implants.
In the prior art, there is also a combination of multi-layer degradable metal materials through electroplating technology. However, the surface of the core layer needs to be chemically treated during electroplating. Requirements for orthopedic implant materials

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medical degradable zinc-based composite material and preparation method and application thereof
  • Medical degradable zinc-based composite material and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A medical degradable zinc-based composite material. The zinc-based composite material is cylindrical and includes an inner layer and an outer layer. The inner layer 1 is magnesium and the outer layer 2 is a zinc alloy; the zinc alloy is composed of metal Zn, The composition of metal Mg and element X, in terms of weight percentages, metal Zn 99.87%, metal Mg 0.01%, element X 0.1%, and the rest are inevitable impurities; the element X is Cu.

[0030] The preparation method of the medical degradable zinc-based composite material includes the following steps:

[0031] (1) Melting: smelting Zn5Mg and Zn9X master alloys using existing technology, and detecting the final composition content of the master alloy; then in a smelting mold with a cylindrical cavity, a magnesium rod with a diameter of 1 mm is fixed to the shaft of the cavity In the center, an inner layer is formed, and the diameter of the inner cavity is 27mm; then, taking the actual measured values ​​of Zn5Mg and Zn9X a...

Embodiment 2

[0037] A medical degradable zinc-based composite material. The zinc-based composite material is cylindrical and includes an inner layer and an outer layer. The inner layer is magnesium and the outer layer is a zinc alloy; the zinc alloy is composed of metal Zn and metal Mg. And element X is composed of 99.83% metal Zn, 0.05% metal Mg, 0.1% element X, and the rest are unavoidable impurities; the element X is Li.

[0038] The preparation method of the medical degradable zinc-based composite material includes the following steps:

[0039] (1) Melting: smelting Zn5Mg and Zn9X master alloys using existing technology, and detecting the final composition content of the master alloy; then in a smelting mold with a cylindrical cavity, a magnesium rod with a diameter of 1 mm is fixed to the shaft of the cavity In the center, an inner layer is formed, and the diameter of the inner cavity is 27mm; then, taking the actual measured values ​​of Zn5Mg and Zn9X as the standard, Zn, Zn5Mg, and Zn9X ...

Embodiment 3

[0045] A medical degradable zinc-based composite material. The zinc-based composite material is cylindrical and includes an inner layer and an outer layer. The inner layer is magnesium and the outer layer is a zinc alloy; the zinc alloy is composed of metal Zn and metal Mg. And element X, in terms of weight percentage, 99.78% metal Zn, 0.1% metal Mg, 0.1% element X, and the rest are inevitable impurities; the element X is Mn.

[0046] The preparation method of the medical degradable zinc-based composite material includes the following steps:

[0047] (1) Melting: smelting Zn5Mg and Zn9X master alloys using existing technology, and detecting the final composition content of the master alloy; then in a smelting mold with a cylindrical cavity, a magnesium rod with a diameter of 1 mm is fixed to the shaft of the cavity In the center, an inner layer is formed, and the diameter of the inner cavity is 27mm; then, taking the actual measured values ​​of Zn5Mg and Zn9X as the standard, Zn, Z...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
lengthaaaaaaaaaa
tensile strengthaaaaaaaaaa
elongationaaaaaaaaaa
Login to View More

Abstract

The invention discloses a medical degradable zinc-based composite material. The medical degradable zinc-based composite material is cylindrical and comprises an inner layer and an outer layer, whereinthe inner layer is magnesium and the outer layer is zinc alloy; and the zinc alloy is composed of metal Zn, metal Mg, element X and inevitable impurities and is prepared from the components in percentage by weight: 96-99.87% of metal Zn, 0.01-1% of metal Mg, 0.1-3% of element X and 0.005-0.02% of inevitable impurities, wherein the element X is any one of Cu, Fe, Mn, Ca, Sr or Li. Meanwhile, the invention further discloses a preparation method of the medical degradable zinc-based composite material and application of the medical degradable zinc-based composite material in preparing orthopedicimplantation instruments. The medical degradable zinc-based composite material takes magnesium as the inner layer and zinc alloy as the outer layer, can be degraded in layers and can be used for the orthopedic implantation instruments, and degradation speed is moderate in the environment of simulated human body fluid at 37 DEG C.

Description

Technical field [0001] The invention belongs to the technical field of biodegradable metals, and specifically relates to a medical degradable zinc-based composite material and a preparation method and application thereof. Background technique [0002] Zinc ion is an essential nutrient element for the human body and participates in many metabolic activities of the human body. The American Institute of Clinical Innovation recommends that the human body must consume 2.5 to 6.4 mg of zinc per day. Adults consume about 300 mg of zinc per day to be toxic. reaction. A zinc-based biodegradable bone nail releases about 0.2-0.3 mg of zinc per day. Even if all of these zinc ions are released into the blood vessels, it is far below the human intake, which means that zinc-based biodegradable orthopedic implants Zinc ions released from the degradation of medical devices will not cause systemic toxicity. The study also found that the transportation of zinc ions in human tissues is very rapid,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C22C18/02C22C18/00C22C1/03C22F1/16A61L31/02A61L31/14
Inventor 宁靠屈功奇吕轲赵志义陈彪屈雁林
Owner 湖南华翔医疗科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com