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A kind of traditional Chinese medicine for treating steroid-induced necrosis of the femoral head and its application

A technology for necrosis of the femoral head and traditional Chinese medicine, which can be used in medical preparations containing active ingredients, pharmaceutical formulas, bone diseases, etc., and can solve problems such as poor prognosis, hip joint dysfunction, and affecting the quality of life of patients.

Active Publication Date: 2021-11-05
THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the most common type of necrosis of the femoral head is steroid-induced necrosis of the femoral head, which mainly occurs in young adults, usually involving both sides, the disease progresses rapidly, and the prognosis is poor, eventually causing hip joint dysfunction and seriously affecting the quality of life of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A traditional Chinese medicine for treating steroid-induced necrosis of the femoral head, which is prepared from the following raw materials in parts by weight: 15-20 parts of epimedium, 15-18 parts of psoralen, 12-18 parts of drynaria, 15-20 parts of chuanxiong 10-12 parts of coix seed. And the traditional Chinese medicine for treating steroid-induced necrosis of the femoral head is made into decoction, pill or capsule.

[0025] Epimedium, Coix Seed, Rhizoma Drynaria and Psoralen used in the formula of the present invention were purchased from Anhui Puren Traditional Chinese Medicine Pieces Co., Ltd., and Chuanxiong was purchased from Anhui Shitian Traditional Chinese Medicine Pieces Co., Ltd.

[0026] The traditional Chinese medicine formula for the treatment of steroid-induced necrosis of the femoral head provided in this example exerts a more significant effect through the interaction between the medicines and promotes each other, so that the Qi and blood can be unb...

Embodiment 2

[0028] A traditional Chinese medicine for treating steroid-induced necrosis of the femoral head, which is prepared from the following raw materials in parts by weight: 17.5 parts of epimedium, 16.5 parts of psoralen, 15 parts of drynaria, 17.5 parts of chuanxiong and 11 parts of coix seed.

[0029] The preparation method of the above-mentioned traditional Chinese medicine for treating steroid-induced femoral head necrosis, the specific steps are as follows: take the above-mentioned raw materials in parts by weight, add water 7 times the total weight of medicinal materials, soak for 1.5 hours, boil on high heat, decoct with slow fire for 30 minutes, cool, and filter to obtain The filtrate is the decoction.

[0030] The traditional Chinese medicine formula for the treatment of steroid-induced necrosis of the femoral head provided in this example exerts a more significant effect through the interaction between the medicines and promotes each other, so that the Qi and blood can be ...

Embodiment 3

[0032] A traditional Chinese medicine for treating steroid-induced necrosis of the femoral head, which is prepared from the following raw materials in parts by weight: 16 parts of epimedium, 15.5 parts of psoralen, 17 parts of drynaria, 16.5 parts of chuanxiong, and 11.5 parts of coix seed.

[0033] The preparation method of the above-mentioned Chinese medicine for the treatment of steroid-induced necrosis of the femoral head, the concrete steps are as follows:

[0034] Take the above-mentioned raw materials by weight, add water that is 8 times the total weight of medicinal materials, soak for 1 hour, boil on high heat, decoct with slow fire for 30 minutes, cool, filter to obtain the filtrate, and concentrate the filtrate to a clear paste with a relative density of 1.20. Measured at ℃, and dried under reduced pressure to form an extract; then add an appropriate amount of starch and dextrin to mix, granulate, dry, and compress into tablets to form tablets, each 0.5g.

[0035] T...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine for treating steroid-induced necrosis of the femoral head and its application. ‑18 parts, Chuanxiong 15‑20 parts, coix seed 10‑12 parts. The traditional Chinese medicine formula for the treatment of steroid-induced femoral head necrosis provided by the invention exerts a more significant effect through the interaction between the medicines and promotes each other, so that the Qi and blood can be unblocked, the liver and kidney can be nourished, and the kidney yang can be strengthened, the bones and muscles can be strengthened, and the blood can be circulated. It can treat both symptoms and root causes of steroid-induced necrosis of the femoral head, and the curative effect is remarkable.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating steroid-induced necrosis of the femoral head and its application. Background technique [0002] Femoral head necrosis is a pathological process caused by the destruction of the blood supply of the femoral head or the death of the active components of bone cells (bone cells, bone marrow cells and fat cells) due to different etiologies. Clinically, it can be divided into two categories: traumatic and non-traumatic. The pathogenesis of the former is relatively clear, while the latter is often a complication of systemic diseases, and the pathogenesis is still unclear. [0003] Steroid-induced necrosis of the femoral head is a non-traumatic necrosis of the femoral head, which mostly occurs in the avascular necrosis of the femoral head caused by long-term or high-dose application of adrenal corticosteroids that exceed th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P19/08
Inventor 李慧英孟东方于建伟
Owner THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
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