In-vitro double dynamic degradation performance analysis device for medical magnesium alloy implant material

Abstract

The invention discloses an in-vitro double dynamic degradation performance analysis device for a medical magnesium alloy implant material. A base is provided with a computer, an electrochemical workstation, a motor, a sample tank, a speed regulating peristaltic pump and a thermostatic bath. The motor drives a crank mechanism through a belt, a pinion and a large gear. The tail end of the crank mechanism is fixedly connected with the upper end of a swing rod, the lower end of the swing rod is provided with a sample, and the swing rod is inserted into a sample groove. The sample groove, the speedregulating peristaltic pump and a liquid storage tank in the thermostatic bath are in communication with each other to form a circulation flow channel. The sample tank is provided with a first thermometer, a pH meter and a flowmeter, and the liquid storage tank is provided with a second thermometer. The data output ends of the first thermometer, the pH meter, the flowmeter and the second thermometer are connected with the computer, and the control signal input ends of the motor, the speed regulating peristaltic pump and the thermostatic bath are connected with the computer. The electrochemical workstation is connected with electrodes in the sample tank to connect with samples, and the electrochemical workstation is in bidirectional data connection with the computer.

Description

technical field [0001] The invention relates to a device for analyzing the degradation performance of medical materials in a simulated human body environment, specifically a device for analyzing the double dynamic degradation performance of medical magnesium alloy implant materials in vitro. Background technique [0002] Magnesium and magnesium alloys are known as "green engineering materials in the 21st century". As structural metal materials, they have excellent mechanical properties. At the same time, magnesium and magnesium alloys also have unique biocompatibility and degradability. The application has received widespread attention, and its use as a new type of degradable medical implant material has always been a research hotspot by scholars at home and abroad. However, magnesium has high activity, and it is prone to corrosion and degradation in aqueous solution or humid environment. Therefore, in the acidic physiological environment of the human body, medical magnesium...

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Problems solved by technology

However, current research focuses on in vitro static immersion experiments, that is, static immersion of medical magnesium alloy implant materials in simulated body fluids, so as to study the in vitro degradation performance of magnesium alloy implant materials, but such static immersion experiments cannot be achieved in the human body. The real simulation of the special environment ignores the constant temperature environment in the human body, the flow of body fluids, and the dual dynamic environment of the movement of human organs on the corrosion and degradation of medical magnesium alloy implant materials, and cannot monitor the simulated body fluid temperature and pH value during the dynamic corrosion degradation process in vitro At the same time, in general in vitro static immersion experiments, the method of drying and weighing the sample or the method of hydrogen evolution is often used to intuitively and roughly estimate the degradation rate. This method is cumbersome and has certain errors that cannot be accurate. It took a lot of manpower and material resources to measure its degradation rate

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