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Traditional Chinese medicine composition with skin freckle removal effect and water extract, fermented product and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition, can solve the problems of difficulty in achieving, inaccurate effect, aggravated and rebound of pigmentation, etc., and achieve the effects of wide application range, simple and convenient addition, and good compatibility.

Active Publication Date: 2019-02-22
温州古木生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Laser is being more and more widely used in the treatment of pigmentation, but the effect is not exact, and there is a potential risk of hyperpigmentation rebound after treatment, making it difficult to achieve the desired goal
However, commonly used tyrosinase inhibitors such as hydroquinone, retinoic acid, or azelaic acid, which has anti-proliferation and toxicity effects on melanocytes, as well as antioxidant agents, chemical peeling, and glucocorticoids, all have obvious effects. Toxic side effects and risk of skin stratum corneum damage

Method used

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  • Traditional Chinese medicine composition with skin freckle removal effect and water extract, fermented product and application thereof
  • Traditional Chinese medicine composition with skin freckle removal effect and water extract, fermented product and application thereof
  • Traditional Chinese medicine composition with skin freckle removal effect and water extract, fermented product and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1: Application of the water extract of the traditional Chinese medicine composition in the repair essence.

[0031] Preparation of the water extract of the traditional Chinese medicine composition: weigh 150g of triangular ribs, 150g of spatholobi, 150g of angelica, 80g of codonopsis, 80g of radix rehmanniae, 80g of white fresh peel, and 80g of licorice, and pack them in sterilized gauze bags after washing. In a vacuum homogenizing emulsifying pot, adding 10 times the pure water according to the weight of the traditional Chinese medicine composition, extracting at 95-100°C for 1 hour, and filtering the medicinal juice to obtain an aqueous extract of the traditional Chinese medicine composition.

[0032] The formula of the water extract repair essence containing 20wt% Chinese medicine composition is shown in Table 1:

[0033]

[0034] Table 1

[0035] The components in the formula of Table 1 were prepared according to the following process:

[0036] (1) First weigh each c...

Embodiment 2

[0039] Example 2: It is the application of traditional Chinese medicine composition in repairing emulsion.

[0040] Preparation of the water extract of the traditional Chinese medicine composition: weigh 250g tricorne, 250g of spatholobi, 250g of angelica, 150g of codonopsis, 150g of rehmannia, 150g of white fresh peel, and 150g of licorice, and pack it in sterilized gauze bag after washing. In a vacuum homogenizing emulsifying pot, adding 10 times the pure water according to the weight of the traditional Chinese medicine composition, extracting at 95-100°C for 1 hour, and filtering the medicinal juice to obtain an aqueous extract of the traditional Chinese medicine composition.

[0041] The formula of the water extract repair emulsion containing 25wt% Chinese medicine composition is shown in Table 2:

[0042]

[0043]

[0044] Table 2

[0045] The components in the formula of Table 2 were prepared according to the following process:

[0046] (1) First weigh each component according to...

Embodiment 3

[0066] Example 3: Application of fermented traditional Chinese medicine in repair essence.

[0067] Preparation of fermented traditional Chinese medicine: weigh 150g tricorne, 150g of spatholobi, 150g of angelica, 80g of Codonopsis, 80g of raw rehmannia, 80g of white fresh skin, 80g of licorice, wash it and put it in a fermentation tank, add 120g of high-active dry yeast With 10 times the weight of pure water, fermented for 4 hours at 42°C and 0 rpm, sterilized and filtered to obtain the filtrate, and then the fermented Chinese medicine can be prepared.

[0068] The formula of the repair essence containing 20wt% fermented Chinese medicine is shown in Table 5:

[0069]

[0070] table 5

[0071] The components in the formula of Table 5 were prepared according to the following process:

[0072] (1) First weigh each component according to the component name and weight in the above table and put it into the mixing pot;

[0073] (2) Mix and stir the 8 components in phase A until they are comp...

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Abstract

The invention relates to the technical field of traditional Chinese medicine compositions with skin freckle removal effect, in particular to a traditional Chinese medicine composition with a skin freckle removal effect and a water extract thereof, fermented product and application thereof. According to the traditional Chinese medicine composition, rhizoma sparganii, caulis spatholobi, angelica, codonopsis, dried rehmannia root, cortex dictamni and licorice are effectively combined to obtain the extract obtained by water extraction and the fermented product by yeast fermentation of the composition; the traditional Chinese composition can directly act on the skin freckle parts, is free of toxic and side effects, simple and safe to use and mild in effects, has the functions of promoting bloodcirculation, preventing blood stasis, resisting oxidation, antagonizing gonadotropin and regulating immune function, and is capable of improving the blood rheology of the freckle parts, reducing theestrogen level and inhibiting the tyrosinase activity so as to inhibit the melanocyte activity and melanin metabolism, destroy and eliminate melanin and then achieve the skin freckle removal effect.

Description

Technical field [0001] The invention relates to the technical field of a traditional Chinese medicine composition with skin freckle removal effect, in particular to the effect of removing chloasma and post-inflammatory pigmentation, and in particular to a traditional Chinese medicine composition with skin freckle removal effect and its water extract and fermented product And application. Background technique [0002] There are many factors that affect the color of skin peptides, among which melanin is the main factor that determines skin color. Melanin is the main pigment that makes the skin brown and black, and it is produced by tyrosine under the action of tyrosinase. Pigmentation is a kind of hyperpigmentation skin diseases, including hyperpigmentation skin diseases and hypopigmentation skin diseases. Freckle removal referred to in the present invention specifically refers to the removal of melasma and post-inflammatory hyperpigmentation skin diseases. [0003] Melasma is an a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/902A61K8/9794A61K8/9789A61Q19/02A61P17/16A61P29/00
CPCA61K36/232A61K36/344A61K36/484A61K36/486A61K36/75A61K36/804A61K36/902A61K2236/19A61K2236/331A61K2800/782A61K2800/85A61Q19/02A61K8/9789A61K8/9794A61P17/16A61P29/00A61K2300/00
Inventor 陈克陈万胜
Owner 温州古木生物科技有限公司
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