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Traditional Chinese medicine composition for treating canine enteritis type parvovirus as well as preparation method and application thereof

A technology of parvovirus and composition, applied in the field of traditional Chinese veterinary medicine, can solve the problems of low vaccine protection rate, large side effects, difficult prevention and the like

Inactive Publication Date: 2019-02-22
JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the high variability of CPV, it has brought certain difficulties to its prevention, and the disease often occurs due to the low protection rate of the vaccine.
In addition, the current treatment of CPV often uses hyperimmune serum, ribavirin, penicillin, gentamicin, dexamethasone, hemostatic drugs, vitamin B, vitamin C and symptomatic therapy, the treatment effect is not ideal and the side effects are great

Method used

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  • Traditional Chinese medicine composition for treating canine enteritis type parvovirus as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Prescription: 12 grams of Dafeng medicine, 17 grams of pomegranate leaves, 16 grams of Sichuan berries, 12 grams of inverted roots

[0061] The specific preparation method is as follows: mix the four traditional Chinese medicines of Dafeng medicine, pomegranate leaf, Chuanberry, and rooting root, add 5 times the weight of the total medicinal materials in water, soak for 30 hours, decoct twice, concentrate the decoction until thick, add 95% Ethanol is adjusted to ethanol concentration and is 60%, after fully stirring, refrigerated precipitation, filtration, collects filtrate and reclaims the ethanol in filtrate, is that the mass concentration of 95% ethanol is adjusted to ethanol concentration in the medicinal liquid after above-mentioned reclaiming ethanol again. 75%, stir well, refrigerate, precipitate, filter, collect the filtrate and recover ethanol, then concentrate until there is no alcohol smell, and the medicinal solution is concentrated; the concentration reached...

Embodiment 2

[0063] Prescription: 14 grams of Dafeng medicine, 20 grams of pomegranate leaves, 18 grams of Chuanberry, 10 grams of inverted root, the specific preparation method is as follows:

[0064] Mix Dafeng medicine, pomegranate leaves, Sichuan berries, and inverted root, add 4 times the total weight of 4 kinds of Chinese medicinal materials, soak in water for 24 hours, decoct 3 times, concentrate the decoction to a thick state after combining, add ethanol with a mass concentration of 95% Adjust the ethanol concentration to 65%, stir well, refrigerate, precipitate for 48 hours, and recover ethanol. Add ethanol with a mass concentration of 95% to 75% of the medicinal solution after recovering ethanol, stir evenly, refrigerate and precipitate for 48 hours, recover ethanol, and then concentrate until there is no alcohol smell, and continue to concentrate the medicinal solution to reach a concentration of 1 gram of crude drug per milliliter.

Embodiment 3

[0066] Prescription: 18 grams of Dafeng medicine, 17 grams of pomegranate leaves, 30 grams of Sichuan berries, 14 grams of inverted roots

[0067] The specific preparation method is as follows:

[0068] Mix Dafeng medicine, pomegranate leaves, Sichuan berries, and inverted roots, add 5 times the total weight of 4 kinds of Chinese herbal medicines, soak in water for 24 hours, decoct 3 times, concentrate the decoctions until thick, add 95% of the mass concentration The ethanol was adjusted to ethanol concentration of 70%, fully stirred, refrigerated, precipitated for 48 hours, and the ethanol was recovered. Add ethanol with a mass concentration of 95% to the ethanol concentration of 80% after recovering the ethanol, stir and refrigerate and precipitate for 48 hours, recover ethanol, concentrate until no alcohol smell, and continue to concentrate the liquid to reach 2 grams of crude drug per ml concentration.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating canine enteritis type parvovirus as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises the following Chinese medicinal herbs in parts by weight: 10-30 parts by weight of rhamnus napalensis, 15-45 parts by weight of pomegranate leaves, 14-42 parts by weight of rubus setchuenensis and 9-27 parts by weight of korean raspberry roots. The traditional Chinese medicine composition provided by the invention has the advantages that both symptoms and root causes are addressed, and the composition is high in overall curative effect, short in treatment period, unlikely to cause drug resistance, low in residue, small in toxic or side effects and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese veterinary medicine, and relates to a traditional Chinese medicine composition for treating canine enteritis-type parvovirus, and also relates to a preparation method of the Chinese medicine composition and the use of the traditional Chinese medicine composition in preparing Chinese veterinary medicine for treating canine enteritis-type parvovirus Applications. Background technique [0002] Canine parvovirus disease is an acute, febrile, infectious disease caused by canine parvovirus (Canine parvovirus, CPV), which is clinically characterized by hemorrhagic enteritis or non-suppurative myocarditis. Dogs of different ages, genders, and breeds can be infected, and the mortality rate is high. It is one of the main diseases that endanger the dog industry. In 1978, for the first time, CPV was isolated from sick dogs suffering from enteritis. The sick dogs were mainly characterized by vomit...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P31/20
CPCA61K36/72A61K36/185A61K36/73A61K2236/331A61K2236/333A61K2236/39A61K2236/55A61P31/20A61K2300/00
Inventor 戴丽红
Owner JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE
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