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A whitening sunscreen W/O/W multiple emulsion and a preparation method thereof

A multi-emulsion and whitening technology, applied in pharmaceutical formulations, cosmetic preparations, cosmetic preparations, etc., can solve the problems of skin irritation, low extraction efficiency of active raw materials, and fast release speed of whitening ingredients, so as to reduce irritation, The effect of improving bioavailability

Inactive Publication Date: 2019-01-15
SOUTH CHINA UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commonly used whitening active ingredients in whitening cosmetics include arbutin, niacinamide, vitamin C, vitamin A and its derivatives, tranexamic acid, etc., but some whitening ingredients are extremely sensitive to light, oxygen, heat, etc. It is easy to be decomposed, and some whitening ingredients are released too fast in the preparation, which will irritate the skin when the local concentration is too high; chemical sunscreens commonly used in sunscreen cosmetics mainly play a role in sunscreen by absorbing ultraviolet rays of specific wavelengths , when added to a certain concentration, it will affect the skin feel of the product, and the texture is not refreshing enough
[0004] Chinese patent application CN105106039A discloses a preparation method of proanthocyanidin whitening sunscreen. The invention uses macroporous resin separation technology to purify and extract proanthocyanidin to obtain oligomeric proanthocyanidin, which is added to the formula to make moisturizer , to avoid the destruction of its active ingredients and improve the utilization rate, but the active raw materials derived from natural plants have the disadvantage of low extraction efficiency, and the macroporous adsorption resin is expensive, the operation is more complicated, and the cost is higher
Chinese patent application CN101953772A discloses a whitening sunscreen cosmetic and its preparation method and application. The invention uses phospholipids to wrap chemical sunscreens, and natural chitin derivatives to wrap retinol and add them to the composition formula to improve the stability of active substances. Realize the slow release of active substances and reduce skin irritation, but the embedding rate of active substances in phospholipids is low, and the amount of retinol added is limited
Chinese patent CN104042484A discloses a refreshing sunscreen lotion. This invention mixes raw materials and adds multiple moisturizing ingredients to make a refreshing sunscreen lotion. However, due to the small amount of sunscreen added, the sunscreen effect is not good enough

Method used

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  • A whitening sunscreen W/O/W multiple emulsion and a preparation method thereof
  • A whitening sunscreen W/O/W multiple emulsion and a preparation method thereof
  • A whitening sunscreen W/O/W multiple emulsion and a preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The formula of a kind of whitening sunscreen W / O / W multiple emulsion of the present embodiment is as follows:

[0035] Inner water phase:

[0036]

[0037] Oil phase:

[0038]

[0039]

[0040] External aqueous phase:

[0041]

[0042] The preparation method is as follows:

[0043] (1) Put each component in the oil phase into the oil pan and heat it in a constant temperature water bath at 40-50°C until it dissolves evenly. until completely dissolved;

[0044] (2) Add the inner water phase to the oil phase, homogenize in a constant temperature water bath at 40-50°C for 10-15 minutes, then cool to room temperature to obtain W / O colostrum;

[0045](3) Add the components in the external water phase into the water pot and stir until they are completely dissolved. Add the prepared W / O colostrum into the external water phase while stirring at room temperature, stir for 15-20 minutes, and discharge to obtain the Whitening sunscreen W / O / W multiple emulsion.

Embodiment 2

[0047] The formula of a kind of whitening sunscreen W / O / W multiple emulsion of the present embodiment is as follows:

[0048] Inner water phase:

[0049]

[0050]

[0051] Oil phase:

[0052]

[0053] External aqueous phase:

[0054]

[0055] The preparation method is as follows:

[0056] (1) Put each component in the oil phase into the oil pan and heat it in a constant temperature water bath at 40-50°C until it dissolves evenly. until completely dissolved;

[0057] (2) Add the inner water phase to the oil phase, homogenize in a constant temperature water bath at 40-50°C for 10-15 minutes, then cool to room temperature to obtain W / O colostrum;

[0058] (3) Add the components in the external water phase into the water pot and stir until they are completely dissolved. Add the prepared W / O colostrum into the external water phase while stirring at room temperature, stir for 15-20 minutes, and discharge to obtain the Whitening sunscreen W / O / W multiple emulsion.

Embodiment 3

[0060] The formula of a kind of whitening sunscreen W / O / W multiple emulsion of the present embodiment is as follows:

[0061] Inner water phase:

[0062]

[0063] Oil phase:

[0064]

[0065] External aqueous phase:

[0066]

[0067]

[0068] The preparation method is as follows:

[0069] (1) Put each component in the oil phase into the oil pan and heat it in a constant temperature water bath at 40-50°C until it dissolves evenly. until completely dissolved;

[0070] (2) Add the inner water phase to the oil phase, homogenize in a constant temperature water bath at 40-50°C for 10-15 minutes, then cool to room temperature to obtain W / O colostrum;

[0071] (3) Add the components in the external water phase into the water pot and stir until they are completely dissolved. Add the prepared W / O colostrum into the external water phase while stirring at room temperature, stir for 15-20 minutes, and discharge to obtain the Whitening sunscreen W / O / W multiple emulsion.

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Abstract

The invention belongs to the technical field of cosmetics and discloses a whitening sunscreen W / O / W multiple emulsion and a preparation method thereof. The multiple emulsion consists of an internal aqueous phase, an oil phase and an external aqueous phase, wherein the internal aqueous phase comprises 0.1-15 % of whitening antioxidant and 0.1-20 % of water-soluble humectant. The oil phase componentcomprises 0.1% to 5 % of antioxidant, 5% to 18 % of sunscreen, 1% to 7 % of lipophilic emulsifier and 5% to 25 % of lipid solvent; 1% to 5 % of hydrophilic emulsifying agent, 2% to 30 % of water-soluble humectant, 0.1% to 0.8 % of preservative and 0.01% to 0.2 % of water-soluble essence, with the balance being deionized water. As that whiten antioxidant raw material is encapsulated in the water phase in the emulsion, the stability against light, oxygen and heat is increased, and the active substances in the water phase in the emulsion can be slowly and long-term release, the irritation to theskin is reduced, and the bioavailability is improved.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a whitening and sunscreen W / O / W multiple emulsion and a preparation method thereof. Background technique [0002] The ultraviolet radiation in sunlight reaching the surface of the earth is usually divided into two bands, UVA band and UVB band. UVA with longer wavelengths will penetrate deep into the skin, damage the dermis of the skin, and tan the skin, which is an important cause of skin aging. One of the reasons is that the UVB band is the root cause of skin sunburn. In severe cases, erythema and blisters can occur. Strong ultraviolet radiation may also cause skin cancer. [0003] Having healthy and fair skin has become the pursuit of modern people, and cosmetics with both sunscreen and whitening effects have great application potential and value in the market. Commonly used whitening active ingredients in whitening cosmetics include arbutin, niacinamide, vitamin...

Claims

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Application Information

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IPC IPC(8): A61K8/06A61K8/9789A61K8/92A61K8/89A61K8/73A61K8/60A61K8/49A61K8/46A61K8/42A61K8/40A61K8/34A61K8/31A61Q17/04A61Q19/02A61Q19/08A61Q19/00
CPCA61K8/066A61K8/31A61K8/345A61K8/40A61K8/42A61K8/466A61K8/4946A61K8/4973A61K8/4993A61K8/60A61K8/602A61K8/675A61K8/676A61K8/678A61K8/735A61K8/89A61K8/92A61K8/922A61K2800/56A61K2800/5922A61K2800/72A61Q17/04A61Q19/00A61Q19/004A61Q19/02A61Q19/08A61K8/9789
Inventor 胡建强杨佩
Owner SOUTH CHINA UNIV OF TECH
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