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Use collagen and preparation methods for skin repair

A collagen and skin repair technology, applied in the field of peptide or protein preparation, can solve problems such as safety concerns and doubts about the safety of collagen white, and achieve the effects of good solubility, high absorption and high content

Active Publication Date: 2021-08-13
艾苛密(上海)健康科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the collagen used in the market comes from the collagen tissue extracts of mammals or poultry animals such as cattle, pigs, and chickens. One after another, the safety of collagen white from livestock and poultry has been questioned, and some consumers have a tendency to be allergic to collagen from livestock
Therefore, the use of collagen extracted from terrestrial animals has potential safety concerns

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0041] The preparation method of the ginger root extract is as follows: place the ginger root at 50° C. to dry for 6 hours, grind it to 40 meshes and then add it to 50 wt % ethanol aqueous solution, and the mass volume ratio of the ginger root to the 50 wt % ethanol aqueous solution is 1:8 ( g / mL), microwave treatment at 70°C and microwave power of 560W for 5 minutes, filtered through a 100-mesh filter cloth, and the obtained filtrate was placed in a rotary evaporator, concentrated at a temperature of 50°C and an absolute pressure of 0.05MPa Until the water content is 5%, the ginger root extract is obtained.

[0042] The preparation method of perilla leaf extract is as follows: dry perilla leaves at 50°C for 5 hours, crush them to a 40-mesh sieve, add 80wt% ethanol aqueous solution according to a solid-liquid ratio of 1:4, extract at 85°C for 3 hours, After filtering through a 150-mesh filter cloth, the resulting filtrate is concentrated in a rotary evaporator with a temperatu...

Embodiment 1

[0055] A preparation method of collagen for skin repair, comprising the following steps:

[0056] Ⅰ. Soak dried sea cucumbers in deionized water at 50°C, the mass ratio of deionized water to sea cucumbers is 15:1, take out after soaking for 10 hours, let it stand for 15 minutes, drain the water, and cut open the abdomen of sea cucumbers with scissors , remove the spit and wash the sea cucumbers with water at 20°C for 3 times, the mass ratio of water to sea cucumbers used for each washing is 2:1, to obtain pretreated sea cucumbers;

[0057] Ⅱ. Place the above-mentioned pretreated sea cucumbers in the meat grinding equipment at 20°C. The production capacity of the meat grinder is 120kg / h, and the power is 0.55kw. After grinding, the sea cucumbers with a diameter of 6mm are obtained. 1:10 (g / mL) Add deionized water to sea cucumber minced meat, stir at 20°C and 1500r / min for 30min to obtain a homogenate;

[0058] Ⅲ. add 0.5mol / L sodium hydroxide solution to above-mentioned homoge...

Embodiment 2

[0063] It is basically the same as Example 1, except that the deodorizing agent is prepared by mixing ginger root extract and perilla leaf extract in a mass ratio of 1:1.

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Abstract

The invention discloses a collagen for skin repair and a preparation method thereof. The present invention uses sea cucumbers as raw materials, adopts methods such as ultra-high pressure treatment, protease enzymatic hydrolysis, etc. to process sea cucumbers, and simultaneously uses deodorizing agents to deodorize the enzymatic solution, so that the prepared collagen for skin repair has a high content of active ingredients. It has good solubility, high absorption, and no fishy smell. It has various functions such as anti-oxidation, anti-inflammation, DNA protection, moisturizing ability, anti-wrinkle function and skin whitening effect. It can be used as a raw material for cosmetics, nutritional health products, food and Medical and other fields.

Description

technical field [0001] The invention relates to a preparation method of peptide or protein, in particular to collagen for skin repair and a preparation method thereof. Background technique [0002] Collagen is an important functional protein. It has attracted widespread attention because of its strong biological activity and biological function. It has huge market potential and high economic value. It has been widely used in beauty care, medicine, food, and daily use. Chemical industry, biosynthesis, pharmaceutical capsules and other fields. [0003] At present, most collagen treatment methods include acid method, alkali method, enzymatic method, salt method and hot water extraction method, etc. Among them, the enzymatic method has mild conditions and less environmental pollution, which is superior. Most of the collagen used in the market comes from the collagen tissue extracts of mammals or poultry animals such as cattle, pigs, and chickens. One after another, the safety ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07K14/78C12P21/06A61K8/65A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/65A61Q19/00A61Q19/02A61Q19/08C07K14/78C12P21/06
Inventor 张露引
Owner 艾苛密(上海)健康科技股份有限公司
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