Oral donkey-hide gelatin preparation and preparation method thereof
A technology of oral preparations and donkey-hide gelatin, which is applied in the field of donkey-hide gelatin oral preparations and its preparation, can solve the problems of donkey-hide gelatin component loss, uneven composition of donkey-hide gelatin, and destruction of donkey-hide gelatin nutrients, and achieve high absorption efficiency
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[0028] The preparation method of the donkey-hide gelatin oral preparation includes the following steps:
[0029] S1. Mix the superfine powder of donkey-hide gelatin with purified water, ultrasonically treat it for 20-30 minutes, stir continuously during the ultrasonic treatment, and then increase the temperature to pressurize the glue to obtain a melted glue solution, the temperature of which is 70-90°C , The pressure is 0.3-0.4Mpa, and the time for gelatinization is 0.5-1h;
[0030] S2. The rock sugar is melted into a syrup with purified water, precipitated for 2-4h, filtered through a 100-110 mesh sieve, pumped into the melted gum solution obtained from the treated S1, add soybean oil, tea oil and yellow wine and mix well. Stir at 1500-2500r / min for 1-2h to obtain material a;
[0031] S3. Mix Jerusalem artichoke, astragalus, medlar and purified water evenly, soak in 25% ethanol solution for 20-26h, percolate at 2ml / min, and evaporate and concentrate to obtain material b;
[0032] S...
Embodiment 1
[0037] An oral preparation of donkey-hide gelatin, in parts by weight, comprising the following raw materials: 50 parts of donkey-hide gelatin, 32 parts of rock sugar, 26 parts of soybean oil, 3.8 parts of tea oil, 5.7 parts of yellow wine, 9.8 parts of Jerusalem artichoke, 5.7 parts of fish bone meal, 4.6 parts of astragalus, 13.5 parts of wolfberry, 7.4 parts of chitosan, 18.6 parts of sustained-release aids;
[0038] The sustained-release auxiliary agent is prepared according to the following process: 22.3 parts of α-starch, 3.4 parts of sodium glutamate, 4.2 parts of sugar terpenes, 5.8 parts of spirulina, 4.3 parts of decoction, and 5.7 parts of soy eggs are combined by weight. Mix the phospholipids evenly, stir at 520r / min for 24min, then dry in a freeze dryer at -42℃ for 32min, then add 17 parts of polylactic acid and mix well, stir at 5200r / min for 14min, then add 18 parts of ethanol gel and mix well , Then stirred at 285r / min for 4h, then centrifuged at 10500r / min for co...
Embodiment 2
[0047] An oral preparation of donkey-hide gelatin, in parts by weight, comprising the following raw materials: 5 parts of donkey-hide gelatin, 40 parts of rock sugar, 20 parts of soybean oil, 6 parts of tea oil, 4 parts of yellow wine, 15 parts of Jerusalem artichoke, 4 parts of fish bone meal, 6 parts of astragalus, 8 parts of wolfberry, 9 parts of chitosan, 15 parts of sustained-release aids;
[0048] The sustained-release aid is prepared according to the following process: 15 parts by weight of α-starch, 5 parts of sodium glutamate, 3 parts of sugar terpenes, 8 parts of spirulina, 3 parts of decoating, and 8 parts of soy eggs Phospholipids are mixed uniformly, stirred at 350r / min for 30 minutes, then dried in a freeze dryer at -30°C for 40 minutes, then 12 parts of polylactic acid are added and mixed well, stirred at 5500r / min for 10 minutes, and then 20 parts of ethanol gel are added and mixed well , Then stirred at 250r / min for 5h, then centrifuged at 8500r / min for collectio...
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