A titanium alloy with ultra-high antibacterial properties used in medical implants and its preparation

Abstract

The invention aims to provide an ultrahigh-antibacterial-performance titanium alloy applied to a medical implant and a manufacturing method of the ultrahigh-antibacterial-performance titanium alloy. The ultrahigh-antibacterial-performance titanium alloy and the manufacturing method of the ultrahigh-antibacterial-performance titanium alloy aim to achieve the effects that under the solid solution and aging heat treatment states of the titanium alloy, a function of effectively resisting high-concentration bacteria (larger than (8-9)*10<6> CFU / mL) is achieved, and the corrosion risk of bacteria microorganisms caused by the use of the titanium alloy is remarkably reduced. The titanium alloy comprises the following chemical components of, by weight, 5.5-6.5% of Al, 6.5-7.5% of Nb, 1.0-3.0% of Gaand the balance Ti. According to the heat treatment mode after material optimization, the temperature of the solid solution treatment is 950-1000 DEG C, heat preservation is carried out for 1.0-2.0 hours, and the temperature is reduced to the room temperature through water cooling. The ultrahigh-antibacterial-performance titanium alloy is widely applied to the multiple kinds of titanium alloy medical implants which are used in the medical clinic fields of a department of stomatology and a department of orthopedics, and the implants particularly refer to the dental implants, bone screws, bonefracture plates, (knee, ankle, shoulder and hip) joints and other common medical surgical implants.

Description

technical field [0001] The invention relates to the field of medical titanium alloy material implants, in particular to a medical titanium alloy that can resist infection in a human body environment with ultra-high concentration of bacteria and a preparation method thereof. Background technique [0002] With its excellent biocompatibility, corrosion resistance and comprehensive mechanical properties, medical titanium alloy has been widely used in the production of various medical implant materials such as stomatology and orthopedics. In the 1960s, pure Ti began to be used clinically as human implants. However, due to its low strength and poor wear resistance, it can only be used for bone replacement and oral restoration in parts that bear less load. With the development of titanium alloy implant materials, TC4 titanium alloy appeared, but because the V element contained in it can cause toxicity to organisms, and the biological toxicity exceeds the constituent elements of mat...

AI Technical Summary

Problems solved by technology

In the 1960s, pure Ti began to be used clinically as human implants, but due to its low strength and poor wear resistance, it can only be used for bone replacement and oral restoration in parts that bear less load.

[0007] Antibacterial functional metal materials are produced by their own antibacterial properties, but such metal materials currently produced or designed have two important limitations in application, such as figure 1 Shown: (a) For bacterial concentration lower than (1-2)*10 5 The killing time of the low concentration of CFU / mL bacteria and microorganisms needs to be as long as 24 hours; (b) the bacterial concentration is higher than (1-2)*10 6 CFU / mL of high concentration of bacteria and microorganisms can not achieve more than 90% sterilization rate

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