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Fat injection applied to injection cosmetology and preparation method

An injection and fat technology, applied in the field of injection beauty, can solve the problems of low survival rate of transplanted fat, poor cosmetic effect of injection, liquefaction of transplanted fat, etc., to improve the concentration and survival rate, ensure the curative effect, and promote the effect of autologous fat growth.

Inactive Publication Date: 2018-10-19
CHENDU NEW KELI CHEM SCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Aiming at the currently widely used adipose tissue filling cosmetology injection cosmetology, which generally uses autologous direct filling, there is a low survival rate of transplanted fat, and problems such as liquefaction and necrosis of transplanted fat are prone to occur, resulting in poor cosmetic effect of injection. The present invention proposes a method for injection Fat injection and preparation method for beauty, thereby effectively improving the concentration and survival rate of fat stem cells, ensuring the remarkable curative effect of cosmetic plastic surgery

Method used

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  • Fat injection applied to injection cosmetology and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The preparation process is:

[0036] (1) Extraction of autologous inner thigh fat;

[0037] (2) The fat is frozen and ground by liquid nitrogen; the temperature of the frozen grinding is -50°C, and the particle size of the ground fat is 50 μm.

[0038] (3) Rinse the ground fat with brine under nitrogen atmosphere; the mass concentration of brine is 30%.

[0039] (4) Add water and an emulsifier to the fat, followed by ultrasonic emulsification to obtain an emulsion; the emulsifier is polyethylene glycol. The ultrasonic processing frequency is 300 kHz, and the processing time is 40 min. In the emulsion, 30 parts by weight of fat, 69 parts by weight of water, and 1 part by weight of emulsifier.

[0040](5) Add nano-scale silica airgel into the emulsion, disperse evenly, and then add a demulsifier to destroy the emulsion system, and a large number of fat stem cells remain in the pores of nano-scale silica airgel; the demulsifier is poly Oxyethylene polyoxypropylene stea...

Embodiment 2

[0047] The preparation process is:

[0048] (1) Extraction of autologous inner thigh fat;

[0049] (2) Freezing and grinding the fat with liquid nitrogen; the temperature of the freezing and grinding is -20°C, and the particle size of the ground fat is 100 μm.

[0050] (3) Rinse the ground fat with brine under nitrogen atmosphere; the mass concentration of brine is 30%.

[0051] (4) Add water and an emulsifier to the fat, followed by ultrasonic emulsification to obtain an emulsion; the emulsifier is sodium dodecylsulfonate. The ultrasonic processing frequency is 200 kHz, and the processing time is 50 min. In the emulsion, 35 parts by weight of fat, 63 parts by weight of water, and 2 parts by weight of emulsifier.

[0052] (5) Add nano-scale silica airgel into the emulsion, disperse evenly, and then add a demulsifier to destroy the emulsion system, and a large number of fat stem cells remain in the pores of nano-scale silica airgel; the demulsifier is poly Oxyethylene polyo...

Embodiment 3

[0059] The preparation process is:

[0060] (1) Extraction of autologous inner thigh fat;

[0061] (2) The fat is frozen and ground by liquid nitrogen; the temperature of the frozen grinding is -40°C, and the particle size of the ground fat is 150 μm.

[0062] (3) Rinse the ground fat with brine under nitrogen atmosphere; the mass concentration of brine is 30%.

[0063] (4) Add water and an emulsifier to the fat, followed by ultrasonic emulsification to obtain an emulsion; the emulsifier is fatty acid polyoxyethylene ether. The ultrasonic processing frequency is 300 kHz, and the processing time is 40 min. In the emulsion, 30 parts by weight of fat, 68 parts by weight of water, and 2 parts by weight of emulsifier.

[0064] (5) Add nano-scale silica airgel into the emulsion, disperse evenly, and then add a demulsifier to destroy the emulsion system, and a large number of fat stem cells remain in the pores of nano-scale silica airgel; the demulsifier is fat Alcohol Sulfate. ...

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Abstract

The invention provides fat injection applied to injection cosmetology and a preparation method. The preparation method comprises the following steps: firstly, extracting autologous inner thigh fat; freezing and grinding the autologous inner thigh fat; washing under the nitrogen environment; adding water and an emulsifier to obtain emulsion; then adding nanoscale silicon dioxide aerogel and a demulsifier into the emulsion; evenly dispersing and centrifugally separating the mixture to obtain adipose-derived stem cells; finally, matching the adipose-derived stem cells with vitamin C, collagen andhyaluronic acid to prepare the fat injection applied to injection cosmetology. According to the method, the fat is emulsified and dispersed into silicon dioxide aerogel with nano pores, and the adipose-derived stem cells are preserved in the silicon dioxide aerogel after demulsification; thus, the concentration and the survival rate of the adipose-derived stem cells are improved; when being applied to injection cosmetology, the high-concentration adipose-derived stem cells can promote autologous fat growth and have obvious treating effects on the plastic and aesthetic surgery aspects of rhytidectomy, lip enhancement, chin augmentation, rhinoplasty, nasolabial grooves and the like.

Description

technical field [0001] The invention relates to the field of cosmetic injections, in particular to the preparation of fat injections, in particular to a fat injection for cosmetic injections and a preparation method. Background technique [0002] Injection cosmetology is a cosmetic method that injects filling substances into parts of the human body to correct skin defects. Injection cosmetology is a kind of non-surgical plastic cosmetology. It uses injection method to inject biomaterials or synthetic biocompatible materials into the dermis or subcutaneous layer to reduce skin wrinkles or shape through different mechanisms. The method is safe, painless and efficient. The main advantage of injection cosmetic surgery is that the trauma is small. Compared with traditional plastic surgery, the damage caused by injection cosmetic surgery is only one or a few pinholes, and the recovery time is short or even no recovery time; cheap is injection cosmetic surgery. Another advantage ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/50A61L27/38A61L27/02
CPCA61L27/50A61L27/025A61L27/3804A61L2400/06A61L2430/34
Inventor 陈庆曾军堂
Owner CHENDU NEW KELI CHEM SCI CO LTD
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