Povidone-iodine pharmaceutical composition for treating skin and mucosa infection as well as preparation method and application thereof
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A technology of povidone-iodine and composition, applied in the field of medicine, can solve the problems of lack of laboratory indicators and the like
Inactive Publication Date: 2018-09-07
乐泰药业有限公司
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Due to the unknown etiology, the diagnosis of oral ulcers is entirely based on medical history an
Method used
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Embodiment l
[0046] Embodiment 1: the preparation of povidone-iodine solution (1000ml)
[0047] (1) Weigh 10 g of povidone-iodine, add 9 times its weight in purified water, soak for 24 hours, and set aside.
[0048] (2) Take purified water according to 2 / 3 of the total weight of the povidone-iodine solution to be prepared, add the povidone-iodine solution obtained in step (1) under stirring, and continue to stir for 15 minutes to make it dissolve (no visible insoluble After that, add purified water to make the total volume 1000ml, stir for 30 minutes, filter, and set aside.
[0049] (3) Filling: Fill the prepared liquid medicine into high-density polyethylene bottles (HDPE) and polyester bottles (PET).
Embodiment 2
[0050] Embodiment 2: the preparation of povidone-iodine solution (1000ml)
[0051] (1) Take purified water according to 2 / 3 of the total weight of povidone iodine solution to be prepared, add povidone iodine 10g under stirring, add diethylene glycol monoethyl ether 5ml simultaneously, continue to stir for 15 minutes to make After povidone-iodine is completely dissolved (no visible insoluble matter), add purified water to make up to 1000ml, stir for 30 minutes, filter, and set aside;
[0052] (2) Filling: Fill the prepared medicinal liquid into high-density polyethylene bottles (HDPE) and polyester bottles (PET), and the product is ready.
Embodiment 3
[0053] Embodiment 3: the preparation of povidone-iodine solution (1000ml)
[0054] (1) Take purified water according to 2 / 3 of the total weight of povidone iodine solution to be prepared, add povidone iodine 10g under stirring, add diethylene glycol monoethyl ether 10ml simultaneously, continue to stir for 15 minutes to make After povidone-iodine is completely dissolved (no visible insoluble matter), add purified water to make up to 1000ml, stir for 15 minutes, filter, and set aside;
[0055] (2) Filling: Fill the prepared medicinal liquid into high-density polyethylene bottles (HDPE) and polyester bottles (PET), and the product is ready.
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Abstract
The invention discloses a povidone-iodine pharmaceutical composition for treating skin and mucosa infection as well as a preparation method and application thereof. The pharmaceutical composition is prepared from a povidone-iodine solution and various vitamin zinc tablets, wherein the various vitamin zinc tablets contain zinc gluconate, thiamine hydrochloride (vitamin B1), riboflavin (vitamin B2),pyridoxine hydrochloride (vitamin B6), nicotinic acid and D-alpha-tocopheryl acid succinate. Preferably, the pharmaceutical composition further contains Dingpeng cream. According to the povidone-iodine pharmaceutical composition, the povidone-iodine solution and the various vitamin zinc tablets are combined to use, so that dual effects of prevention and treatment are realized; the povidone-iodinepharmaceutical composition is used for treating both cause and symptoms and accelerating wound healing and has a reliable curative effect. Meanwhile, by matching with the Dingpeng cream, the breedingof the oral pathogens is effectively inhibited, the oral environment is good and the wound is promoted to heal; the povidone-iodine pharmaceutical composition is used for effectively preventing oraldiseases from occurring. The invention provides an effective technical means for treating the skin and mucosa infection.
Description
technical field [0001] The invention relates to a pharmaceutical composition and its application, in particular to a povidone-iodine pharmaceutical composition for treating skin and mucous membrane infection and its preparation method and application, belonging to the technical field of medicine. Background technique [0002] Povidone-iodine (PVP-I) is a yellow-brown to reddish-brown amorphous powder, which is formed by polyvinylpyrrolidone (Povidone, PVP) and iodine in the form of complexation with the help of hydrogen bonds and other external forces. Amorphous complex iodine is a kind of iodophor. Polyvinylpyrrolidone (PVP) is a kind of non-ionic water-soluble polymer with excellent performance and wide application. Since PVP not only has excellent solubility, chemical stability, film-forming properties, low toxicity, physiological inertness and adhesive ability, but also can be combined with many inorganic and organic substances, PVP is gradually widely used in medicine,...
Claims
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