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Hematodialysis concentrate for improving residual renal function

A technology of hemodialysis and concentrates, applied in blood diseases, drug combinations, extracellular fluid diseases, etc., can solve problems such as loss, slow renal function, and patients lose the value of traditional Chinese medicine treatment, and achieve increased excretion rate and anti-platelet aggregation , Improve the effect of residual renal function

Active Publication Date: 2018-08-21
吉林省富生医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is an irresistible slow or rapid loss of residual renal function in hemodialysis patients, and some patients undergoing multiple or even one hemodialysis may lead to rapid loss of residual renal function, making patients lose the value of traditional Chinese medicine treatment and have to completely Reliance on dialysis or kidney transplantation, which is one of the important reasons why many patients refuse hemodialysis

Method used

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  • Hematodialysis concentrate for improving residual renal function
  • Hematodialysis concentrate for improving residual renal function
  • Hematodialysis concentrate for improving residual renal function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A hemodialysis concentrate for improving residual renal function, comprising component A and component B, the composition of component A is as follows: 1023-1124 g of sodium chloride, 0-52 g of potassium chloride, 32-45 g of calcium chloride, 9-26g of magnesium chloride, 21-90g of pH adjuster; the composition of component B is as follows: 714-960g of sodium bicarbonate.

[0025] Prepare A concentrate and B concentrate with 5L and 10L of dialysis water respectively for component A and component B.

Embodiment 2

[0027] A hemodialysis concentrate for improving residual renal function, comprising component A and component B, the composition of component A is as follows: 1032-1136 g of sodium chloride, 0-52 g of potassium chloride, 32-45 g of calcium chloride, Magnesium chloride 9-26g, pH adjuster 98-132g; the composition of component B is as follows: sodium bicarbonate 714-960g.

[0028] Prepare A concentrate and B concentrate with 5L and 10L of dialysis water respectively for component A and component B.

Embodiment 3

[0030] A hemodialysis concentrate for improving residual renal function, comprising component A and component B, the composition of component A is as follows: sodium chloride 743-798g, potassium chloride 0-55g, calcium chloride 34-47g, 9-28g of magnesium chloride, 22-88g of pH regulator; the composition of component B is as follows: 566-754g of sodium bicarbonate and 262-345g of sodium chloride.

[0031] Prepare A concentrate and B concentrate with 5L and 10L of dialysis water respectively for component A and component B.

[0032] Table 1 Common dialysate group

[0033]

[0034]

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Abstract

The invention relates to a hematodialysis concentrate for improving the residual renal function. The hematodialysis concentrate comprises a hematodialysis concentrate and drugs for promoting blood circulation and removing stasis, and the drugs are ligustrazine, vinpocetine or nimodipine. The hematodialysis concentrate inhibits tubular atrophy and proliferation of fibrous tissues and promotes reversion of disused nephron, improves the blood flow and increases the excretion rate of the renal tubule and the fibrous protein solution, improves blood flow volume of internal arteriovenous fistula, protects the lifeline of a hemodialysis patient, and improves the residual renal function of the residual renal function. The drugs directly permeate to a blood zone from a dialysate zone of a dialyzerin each dialysis treatment and play the roles in preventing platelet aggregation and reducing viscosity of blood in the blood zone, so that a hollow fiber of the dialyzer and a micropore of a dialysismembrane are not easy to block, the effective area for dialysis is kept, the micropore of the dialysis membrane is kept smooth, and the metabolic waste in the blood zone is fully dialyzed and cleared. The hematodialysis concentrate has the functions and effects of expanding arteriole and improving microcirculation and the renal function, and the residual nephron is protected, and the function isimproved.

Description

technical field [0001] The invention relates to a hemodialysis concentrate, in particular to a hemodialysis concentrate for improving residual renal function. Background technique [0002] Residual renal function refers to the filtration and endocrine functions of the kidney tissue that survives the damage of the kidney tissue. Under normal circumstances, as long as there is little residual renal function, the body can also excrete and degrade certain small molecular substances, and produce a certain amount of erythropoietin and active vitamin D 3 . [0003] Hemodialysis is currently the main method for the treatment of uremia. However, there is an irresistible slow or rapid loss of residual renal function in hemodialysis patients, and some patients undergoing multiple or even one hemodialysis may lead to rapid loss of residual renal function, making patients lose the value of traditional Chinese medicine treatment and have to completely Reliance on dialysis or kidney tra...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K33/06A61K33/00A61P7/08A61K31/4375A61K31/4422A61K31/4965
CPCA61K31/4375A61K31/4422A61K31/4965A61K33/00A61K33/06A61K33/14A61P7/08A61K2300/00
Inventor 张海悦魏滢孙景春李雪王姝韩峰韩永双翟硕
Owner 吉林省富生医疗器械有限公司
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