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A spaced non-slip vascular stent capable of chronic drug delivery

A vascular stent and a chronic technology, applied in the field of vascular stents, can solve problems such as poor anti-slip effect, poor thrombolytic treatment effect, and easy slippage, and achieve the effects of enhancing anti-slip effect, prolonging drug action time, and improving anti-slip performance.

Inactive Publication Date: 2019-12-06
青岛市即墨区人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, for the above-mentioned anti-slip vascular stent, there are still the following obvious defects during use: 1. Due to the setting of the upper protrusion and the lower protrusion, only one side of the same section of blood vessel is squeezed, and there is no The pressure of the raised hollow mesh tube wall on the blood vessels is very uniform, which makes the anti-skid effect extremely poor and slips easily;
[0006] 2. When the anti-slip vascular stent is used for support, thrombolytic drugs are usually coated on the outer wall of the vascular stent, but by directly coating the outer wall, after the vascular stent is placed in the blood vessel, the medicinal time is short The blood is flowing, and the effect of thrombolytic therapy is extremely poor

Method used

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  • A spaced non-slip vascular stent capable of chronic drug delivery
  • A spaced non-slip vascular stent capable of chronic drug delivery
  • A spaced non-slip vascular stent capable of chronic drug delivery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0040] Embodiment: Using the vascular stent of the present invention, the drug cavity of the stent is filled with 5 g of the same thrombolytic drug as in the comparative example, and then put into the blood vessel, and the remaining amount of the drug is measured and correspondingly timed.

[0041] The experimental data of the drug action time experiment are shown in Table 1 below:

[0042] Table 1

[0043]

[0044] According to the data in Table 1 above, it can be concluded that after the vascular stent in the embodiment of the present invention is placed inside the blood vessel, the drug action time is significantly improved compared with the drug action time in the comparative example.

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Abstract

The invention discloses a spacing antiskid vascular scaffold capable of slowly discharging drugs. The spacing antiskid vascular scaffold comprises a plurality main scaffolds which are parallelly arranged at intervals, the main scaffolds are fixedly connected through auxiliary scaffolds, a plurality of through holes are formed in the main scaffolds, the auxiliary scaffolds are inserted into the through holes, gaps are reserved among the auxiliary scaffolds and the outer side walls of the main scaffolds, drug cavities are formed among the main scaffolds and the auxiliary scaffolds, and drug discharging holes are formed in one side, close to the outer wall of the corresponding main scaffold, of each drug cavity. According to the vascular scaffold, the main scaffolds are arranged at intervals,antiskid effect is further enhanced, the action time of thrombolysis drugs can be greatly prolonged through action of the drug cavities and the drug discharging holes, and the vascular scaffold is quite effective and worthy of popularization.

Description

technical field [0001] The invention relates to the technical field of vascular stents, in particular to a spaced non-slip vascular stent capable of chronic drug delivery. Background technique [0002] Percutaneous puncture angioplasty, referred to as PTA, is under the guidance of medical imaging equipment, using a puncture needle, a guide wire and a guide sheath to insert a balloon catheter with a tightened stent into a human blood vessel and deliver it to the blood vessel At the stenosis, with the expansion of the balloon, the stent is also stretched. After the balloon is retracted and retracted, the plastically deformed metal stent remains in place and is embedded in the blood vessel, playing the role of dilating the blood vessel. This method is currently widely used in the treatment of cardiovascular diseases. [0003] There are many forms of vascular stents in the prior art. The most common one is that the stent matrix is ​​braided with shape memory alloy wire or cut a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/82
CPCA61F2/82A61F2250/0067
Inventor 李中昕柳光栋杨敏
Owner 青岛市即墨区人民医院
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