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Instant tablet rich in aronia anthocyanins and preparation method thereof

An anthocyanin and instant tablet technology, which is applied in the field of biomedicine, can solve the problems of storage, transportation and use, which are easily destroyed, poor water solubility of anthocyanin powder, and low anthocyanin content, so as to improve the single variety, facilitate promotion, The effect of high anthocyanin content

Inactive Publication Date: 2018-08-17
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, anthocyanins are easily oxidized in the natural environment and are sensitive to environmental conditions such as light and heat. Therefore, they are easily destroyed during production, storage, transportation and use, which limits their application range.
In addition, anthocyanin powder has poor water solubility, and preparing it into capsules or tablets can effectively improve these deficiencies
However, there are few anthocyanin tablet products currently on the market, and most of them contain low anthocyanin content. For example, Tomson BY-HEALTH grape seed vitamin C plus E tablet contains 18.7g of anthocyanin per 100g; Swisse grape seed Each tablet contains 95mg proanthocyanidins

Method used

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  • Instant tablet rich in aronia anthocyanins and preparation method thereof
  • Instant tablet rich in aronia anthocyanins and preparation method thereof
  • Instant tablet rich in aronia anthocyanins and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1: the preparation method of aronia anthocyanin instant tablet

[0044] The preparation method of aronia anthocyanin instant tablet, main steps are as follows:

[0045] (1) Crushing and sieving: Aronia anthocyanin powder, citric acid, sodium bicarbonate, sodium carboxymethyl starch, soluble starch, dextrin, magnesium stearate, aspartame, lactose, etc. 100 mesh sieve for use.

[0046] (2) Mixing of ingredients: prepare 90% edible alcohol solution containing 1% PEG6000 and propylene glycol, weigh a certain amount of raw and auxiliary materials, first spray the citric acid powder with the edible alcohol solution containing 1% PEG6000 and propylene glycol, and mix with After mixing part of the anthocyanin powder, add the remaining raw and auxiliary materials, add only part of the lubricant magnesium stearate, stir and mix with an appropriate amount of wetting agent to prepare a soft material.

[0047] (3) Granulation: Granulate the mixed raw and auxiliary mater...

Embodiment 2

[0063] Embodiment 2: the preparation method of aronia anthocyanin instant tablet

[0064] The preparation method of aronia anthocyanin instant tablet, main steps are as follows:

[0065] (1) Crushing and sieving: Aronia anthocyanin powder, citric acid, sodium bicarbonate, sodium carboxymethyl starch, soluble starch, dextrin, magnesium stearate, aspartame, lactose, etc. 100 mesh sieve for use.

[0066](2) Mixing of ingredients: prepare 80% edible alcohol solution containing 1.5% (PEG6000 and propylene glycol), weigh a certain amount of raw and auxiliary materials, and spray the citric acid powder with the edible alcohol solution containing 1.5% (PEG6000 and propylene glycol) earlier. Wrapped with foam, mix well with part of anthocyanin powder, add remaining anthocyanin powder, sodium bicarbonate, sodium carboxymethyl starch, soluble starch, dextrin, aspartame, lactose, part of magnesium stearate, use Stir and mix an appropriate amount of wetting agent to prepare a soft materi...

Embodiment 3

[0083] Embodiment 3: the preparation method of aronia anthocyanin instant tablet

[0084] The preparation method of aronia anthocyanin instant tablet, main steps are as follows:

[0085] (1) Crushing and sieving: Aronia anthocyanin powder, citric acid, sodium bicarbonate, sodium carboxymethyl starch, soluble starch, dextrin, magnesium stearate, aspartame, lactose, etc. 100 mesh sieve for use.

[0086] (2) Mixing of ingredients: prepare 75% edible alcohol solution containing 2% (PEG6000 and propylene glycol), weigh a certain amount of raw and auxiliary materials, and spray citric acid with 75% edible alcohol solution of 2% (PEG6000 and propylene glycol) earlier. Wrapped in powder, mixed well with part of anthocyanin powder, then added the remaining other raw and auxiliary materials, part of magnesium stearate, stirred and mixed with an appropriate amount of wetting agent to prepare a soft material.

[0087] (3) Granulation: Granulate the mixed raw and auxiliary materials and ...

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Abstract

The invention discloses an instant tablet rich in aronia anthocyanins and a preparation method thereof, and belongs to the field of biomedicine. An aronia anthocyanin extract is used as raw materials,and corresponding medicinal auxiliary materials are adopted for pulverizing, sieving, blending, granulating, drying, granulating and tableting to prepare the instant tablet. An edible alcohol solution containing PEG6000 and propylene glycol is used as a wetting agent, the product dissolves rapidly, and the content of the aronia anthocyanins is high.

Description

technical field [0001] The invention relates to an instant tablet rich in aronia anthocyanins and a preparation method thereof, belonging to the field of biomedicine. Background technique [0002] Aronia berries are rich in anthocyanins and polyphenols, the content of which ranks first among various berries. Anthocyanins are polyphenolic compounds of a class of flavanol monomers and their polymers, and are currently internationally recognized as the most effective natural antioxidants for removing free radicals in the human body. Experiments have shown that its anti-free radical oxidation ability is 50 times that of vitamin E and 20 times that of vitamin C, and it is absorbed quickly and completely. It can reach the highest blood concentration in 20 minutes after oral administration, and its metabolic half-life is as long as 7 hours. However, anthocyanins are easily oxidized in the natural environment and are sensitive to environmental conditions such as light and heat. The...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61K31/353A61K9/20A61K47/36A61P39/06A23L33/00A23L33/105A61K131/00
CPCA23L33/00A23L33/105A23V2002/00A61K9/0095A61K9/2059A61K31/353A61K36/73A61P39/06A23V2200/30A23V2250/2104
Inventor 毛健周志磊巩敏姬中伟
Owner JIANGNAN UNIV
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