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Medical cold compress gel for treating dermatitis and eczema and preparation method thereof

A dermatitis eczema, gel technology, applied in the field of medical materials, can solve the problems of easy drug resistance, poor drug efficacy, toxic side effects, etc., to inhibit the expression of bacterial cell division signals, protect microcirculation, and eliminate harmful substances. effect of substance

Inactive Publication Date: 2018-07-20
东莞御治医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the commonly used eczema treatment methods have certain limitations, such as slow onset, poor efficacy, and some have certain toxic and side effects and are prone to drug resistance.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A spray type medical cold compress gel for dermatitis eczema, in parts by weight, comprises the following components:

[0032] 7 parts of isothiocyanate, 5 parts of peppermint extract,

[0033] 3 parts sumac, 5 parts peel extract,

[0034] 0.5 parts of 2-octenyl succinic anhydride, 1 part of nano-titanium oxide,

[0035] 1 part of polyvinyl alcohol, 2 parts of ethyl p-hydroxybenzoate,

[0036] 1 part of sodium carboxymethylcellulose, 2 parts of glycerin,

[0037] 10 parts of ethanol, 15 parts of water.

[0038] Its preparation method comprises the following steps:

[0039] (1) Mint mint leaves were chopped and dried, ground into powder to obtain mint powder, dispersed in ethanol, stirred and dispersed evenly transferred to a three-necked flask, refluxed at 70°C for 1 hour, cooled to room temperature, filtered, collected Filtrate, made the ethanol dispersion of Peppermint extract;

[0040] (2) Chop and mix pomegranate peel, citrus peel, orange peel, and pomelo peel...

Embodiment 2

[0044] A spray type medical cold compress gel for dermatitis eczema, in parts by weight, comprises the following components:

[0045] 10 parts of isothiocyanate, 7 parts of peppermint extract,

[0046] 4 parts sumac, 6 parts peel extract,

[0047] 0.7 parts of 2-octenyl succinic anhydride, 1.2 parts of nano titanium oxide,

[0048] 2 parts of polyvinyl alcohol, 2 parts of ethyl p-hydroxybenzoate,

[0049] 1.2 parts of sodium carboxymethylcellulose, 3 parts of glycerin,

[0050] 12 parts of ethanol, 20 parts of water.

[0051] Its preparation method comprises the following steps:

[0052] (1) Mint mint leaves were chopped and dried, ground into powder to obtain mint powder, dispersed in ethanol, stirred and dispersed evenly transferred to a three-necked flask, refluxed at 75°C for 1 hour, cooled to room temperature, filtered, collected Filtrate, made the ethanol dispersion of Peppermint extract;

[0053] (2) Mince and mix pomegranate peel, citrus peel, orange peel, and po...

Embodiment 3

[0057] A spray type medical cold compress gel for dermatitis eczema, in parts by weight, comprises the following components:

[0058] 13 parts of isothiocyanate, 9 parts of peppermint extract,

[0059] 5 parts sumac, 7 parts peel extract,

[0060] 0.9 parts of 2-octenyl succinic anhydride, 1.4 parts of nano-titanium oxide,

[0061] 3 parts of polyvinyl alcohol, 2.5 parts of ethyl p-hydroxybenzoate,

[0062] 1.4 parts of sodium carboxymethylcellulose, 4 parts of glycerin,

[0063] 14 parts of ethanol, 24 parts of water.

[0064] Its preparation method comprises the following steps:

[0065] (1) Mint mint leaves were chopped and dried, ground into powder to obtain mint powder, dispersed in ethanol, stirred and dispersed evenly transferred to a three-necked flask, refluxed at 80°C for 1.5h, cooled to room temperature, filtered, Collect the filtrate to obtain the ethanol dispersion of peppermint extract;

[0066] (2) Mince and mix pomegranate peel, citrus peel, orange peel, ...

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Abstract

The invention discloses a spray type medical cold compress gel for treating dermatitis and eczema. The spray type medical cold compress gel comprises, by weight parts, 7-20 parts of isothiocyanate, 5-15 parts of peppermint extract, 3-8 parts of sappan wood, 5-10 parts of peel extract, 0.5-1.5 parts of 2-octenyl succinic anhydride, 1-2 parts of nano titanium oxide, 1-5 parts of polyvinyl alcohol, 2-4 parts of ethyl p-hydroxybenzoate, 1-2 parts of sodium carboxymethyl cellulose, 2-6 parts of glycerin, 10-20 parts of ethanol, and 15-33 parts of water. The invention also discloses a method for preparing the medical cold compress gel. The gel is of a spray type, can have dual effects of quick itching relief and efficient repair, and is good in effect of treating dermatitis and eczema in adultsand children and small in toxic and side effects.

Description

Technical field: [0001] The invention relates to the field of medical materials, in particular to a medical cold compress gel for dermatitis and eczema. Background technique: [0002] Eczema is a common skin inflammation; including contact dermatitis; seborrheic and intertriginous eczema; atopic dermatitis. The incidence rate of eczema is about 75.7%, wherein 66.1% of eczema occurs in autumn and winter (October to March), and 33.9% occurs in spring and summer (April to September). Patients suffering from eczema are often restless due to itching, and it is even more difficult to fall asleep at night. Frequent scratching of the itching can lead to skin bacterial infection, which can easily lead to repeated attacks. [0003] The pathogenesis of eczema is very complex, and there are interactions between intrinsic factors and extrinsic factors, often multifaceted. Extrinsic factors such as climate change in the living environment can affect the occurrence of eczema. External s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/06A61P17/00A61K31/26
CPCA61K9/0014A61K9/06A61K31/26A61K36/185A61K36/48A61K36/534A61K36/752A61K47/38A61K2300/00
Inventor 赵志豪
Owner 东莞御治医疗器械有限公司
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