Preparation method of bioactive glass-wrapping modified zirconium oxide dental ceramic material

Abstract

The invention discloses a preparation method of a bioactive glass-wrapping modified zirconium oxide dental ceramic material. The method comprises the specific steps that a hydrolysable silicon-containing compound, triethyl phosphate and nitrate are dissolved in a solvent, the pH value is adjusted, the mixed solution is subjected to a hydrolytic condensation reaction, and bioactive glass precursorsol is obtained; a zirconium oxide suspension solution which is evenly dispersed in advance is added to the bioactive glass precursor sol and evenly dispersed, the sol is converted into gel through aging, a layer of extremely-thin bioactive glass wraps the peripheries of zirconium oxide particles, and after high-temperature sintering, the bioactive glass-wrapping modified zirconium oxide dental ceramic material is obtained. The zirconium oxide dental ceramic material has good biological activity and excellent mechanical properties, proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells can also be promoted at the same time, and accordingly the material helps to improve the osseointegration capacity; the effect of repairing the dental material is improved, the wider clinical application of the material is promoted, and the material has high social economic value.

Description

technical field [0001] The invention relates to the field of dental restoration medical materials, in particular to a method for preparing a bioactive glass-coated modified zirconia dental ceramic material. Background technique [0002] Tooth loss due to dental caries, periodontitis, dental trauma, etc. is one of the most common oral diseases faced by humans. Before the 1950s, The professor proposed for the first time to use titanium metal to replace the gold and precious metals in the past to become a new oral implant. Since then, dental implants have been hailed as the "third set of teeth" for human beings due to their strong functions and good retention. At present, the mainstream planting products on the market are titanium metal and its alloys. Although they are widely used, they still have problems such as poor aesthetics, toxicity, and poor biomechanical adaptability. Bioceramics, especially zirconia ceramics, have more and more clinical application potential becau...

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Problems solved by technology

Around this mechanism, there are mainly the following three modification methods: the first is to directly compound the second phase material with relatively good biological activity in the zirconia matrix, such as hydroxyapatite, bioactive glass, calcium phosphate, etc., although biological The activity is significantly improved, but because the strength of the second phase is low, it will cause a sharp drop in the overall mechanical strength of the ceramic; Depositing bioactive coatings, such as phosphate coatings, bioactive glass coatings, and hydroxyapatite coatings, this method can significantly improve the bioactivity of ceramic surfaces to a certain extent, and is widely used, but because the surface The bonding between the coating and the substrate is mainly physical bonding, the interface bonding force is not high, it is easy to dissolve and peel off in the oral environment, and the long-term repair effect is not good; the third method is mainly through sandblasting, acid-base treatment , laser or ultraviolet treatment and micropatterning to change the properties of the surface of ceramic materials, such as roughness, superhydrophilicity, or generate Zr-OH, improve the adhesion and integration of cells on the surface of the material, thereby improving the implantation effect, However, the effect obtained by this method is often uncertain, and it is easy to induce the transition from tetragonal phase to monoclinic phase on the surface of zirconia ceramics, which affects the reliability and mechanical stability of the material.

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