Application of merremia yunnanensis extract in drug preparation
A technology of white cloud melon and extract, applied to the new use field of white cloud melon extract in the pharmaceutical field, can solve the problems of increasing the carotid artery and cerebral blood flow of rabbits, prolonging the survival time of mice, etc., and improving the blood flow state. , the effect of improving microcirculation and prolonging survival time
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Embodiment 1
[0026] 1. The white cloud melon medicinal material is cleaned and dried, and then coarsely crushed;
[0027] 2. Take the above-mentioned coarsely crushed medicinal materials and add water to extract twice, add 12 times the amount for the first time, add 8 times the amount for the second time, extract for 1 hour each time, and combine the two extracts;
[0028] 3. The extract was filtered with a membrane, and the filtrate was concentrated under reduced pressure to a specific gravity of 1.30 (60°C) to obtain Baiyun melon liquid extract with a yield of 33.6%;
[0029] 4. Take the above fluid extract and dissolve it in water, then add 0.7% potassium sorbate and 5% glycerin, and finally add water to the specified amount, so that the prepared solution contains 2 grams of Baiyun melon medicinal material per ml, and then use 40% NaOH solution Adjust the pH value to 6.5, mix well, and sterilize to obtain the required Baiyungua oral liquid or mixture for treating cerebrovascular disease...
Embodiment 2
[0031] 1. The white cloud melon medicinal material is cleaned and dried, and then coarsely crushed;
[0032] 2. Take the above coarsely crushed medicinal materials and add 10% ethanol to heat reflux for extraction twice, add 6 times the amount of solvent each time, reflux for 2 hours each time, combine the extracts twice to recover ethanol;
[0033] 3. Add 2 times the amount of water to the extract after recovering the ethanol, boil it, cool it to room temperature, filter it with a membrane, concentrate the filtrate under reduced pressure to a specific gravity of 1.29 (60°C), and set it aside.
[0034] 4. Take the above-mentioned fluid extract, add appropriate amount of sugar powder and dextrin, mix evenly, make granules, vacuum-dry at 60°C, sieve and granulate, pack, and obtain Baiyungua granules for treating cerebrovascular diseases.
Embodiment 3
[0036] 1. The white cloud melon medicinal material is cleaned and dried, and then coarsely crushed;
[0037] 2. Take the above coarsely crushed medicinal materials and add 60% ethanol to heat reflux for extraction 3 times, add 4 times the amount of solvent each time, reflux for 1 hour each time, combine the extracts 3 times to recover ethanol;
[0038] 3. Add 2 times the amount of water to the extract after recovering ethanol, boil it, cool it to room temperature, filter it with a membrane, concentrate the filtrate under reduced pressure until the specific gravity is above 1.30 (60°C), then vacuum dry it at 60°C, crush it, and pass it through 80 mesh Sieve to get the extract powder, the yield is 16.2%;
[0039] 4. Mix 50% by weight extract powder and 50% starch, put it in a ball mill and grind it for 2 hours, mix thoroughly, and make granules with a particle size of over 40 mesh through dry granulation or one-step granulation machine. Add 0.8% magnesium stearate by weight of ...
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