Phase reconstruction method based on wavelet domain regularization

Abstract

The invention relates to a phase reconstruction method based on wavelet domain regularization. The phase reconstruction method comprises placing a knife edge instrument on the plane position of the object to be imaged, acquiring and obtaining a knife edge image, and obtaining a two-dimensional point spread function;. placing the imaging object, imaging the object, and obtaining a phase contrast imaging result; performing two-layer wavelet transformation on the phase contrast imaging result diagram; performing Fourier transformation on the signal of each wavelet channel, and performing regularization processing to obtain the component of the absorbing item in the wavelet channel; performing inverse Fourier transformation on the component of the absorbing item in the wavelet channel to obtain the absorbing item of each channel of the space domain; performing the wavelet inverse transformation so as to obtain the phase contrast image absorbing item after being subjected to the wavelet domain regularization; and obtaining the phase information reconstruction result.

Description

technical field [0001] The invention belongs to the fields of biomedical engineering and medical imaging, and relates to a phase reconstruction method based on wavelet domain regularization. Background technique [0002] Breast cancer is currently the number one "killer" of women. According to the latest statistics in 2015, the number of breast cancer patients and deaths worldwide increased to 1.7 million and 520,000 in 2012, accounting for 25% and 520,000 of all female cancer cases respectively. 15% of cancer deaths [2]. my country has a large population, and the prevalence of breast cancer has shown a clear upward trend in recent years. The diagnosis and treatment of breast cancer has become an increasingly serious social problem that needs to be solved urgently. Early diagnosis is the key to solving this social problem and improving the survival rate and life of patients. The key to quality. [0003] The current main method of routine breast examination is molybdenum (rh...

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Problems solved by technology

[0009] The gist of the present invention is to propose a phase reconstruction method based on wavelet domain regularization, so as to solve the key problems faced by the phase information reconstruction based on similar coaxial phase contrast imaging under the current engineering technology conditions: due to the current engineering conditions, The X light source, non-ideality of the detector and system noise cause the deterioration of the phase contrast image quality and the decrease of the phase contrast. Based on the traditional phase reconstruction method, the accuracy of the phase information reconstruction result cannot be guaranteed.

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