A microfluidic chip-based automatic cell sample pretreatment device for space station

A technology of microfluidic chips and pretreatment devices, applied in the direction of measuring devices, test sample preparation, instruments, etc., can solve the problems that it is difficult to ensure the consistency of the processing effect, so as to avoid excessive participation, control the fluid position, The effect of reducing human error

Active Publication Date: 2019-11-22
NORTHWESTERN POLYTECHNICAL UNIV
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  • Abstract
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Problems solved by technology

However, this pretreatment method still cannot get rid of the dependence on manual operation, requiring the operator to manually complete multiple mixing within about half an hour; and affected by the operator's mixing technology and time control, it is difficult to ensure the consistency of the treatment effect

Method used

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  • A microfluidic chip-based automatic cell sample pretreatment device for space station
  • A microfluidic chip-based automatic cell sample pretreatment device for space station
  • A microfluidic chip-based automatic cell sample pretreatment device for space station

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Embodiment Construction

[0042] The present invention will be described in detail below in conjunction with the accompanying drawings, but all the accompanying drawings are for reference and illustration of the present invention, and are not intended to limit the present invention. Moreover, the chip material, processing method, microstructure size and shape, application objects and fields that can be used in the present invention are not limited to this embodiment.

[0043] Such as Figure 1 to Figure 4 As shown, the microfluidic chip-based automatic cell sample pretreatment device for the space station mainly includes a microfluidic chip 11 , a chip holder 12 , a multi-channel fluid-driven pump, and a controller 14 . The pressure-driven port on the microfluidic chip is connected to the interface above the chip fixture, and the interface on the side of the chip fixture is connected to the multi-channel fluid-driven pump through the microtube. The multi-channel fluid driven pump can be a syringe pump...

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Abstract

The invention discloses a microfluidic-chip-based cell sample auto-pretreating device for space stations. The device comprises a microfluidic chip, a chip fixture, a multichannel fluid drive pump anda controller. The microfluidic-chip-based cell sample auto-pretreating device for space stations may adapt to microgravity environments in space stations and is suitable for independent use in or being integrated to a micro-flow cytometer. The microfluidic chip is available for single use, is inserted and used, prevents excessive intervention of manpower and is convenient to use. The microfluidic-chip-based cell sample auto-pretreating device for space stations has two sample pretreating functions, allows samples to be pretreated by fluid control, and allows the samples to be pretreated continuously and efficiently.

Description

【Technical field】 [0001] The invention relates to the technical field of microfluidic biochips, in particular to a chip device suitable for preparing cell samples before analysis by a microflow cytometer in a space station microgravity environment. The preparation process may include the following steps: staining and lysing of cells. The device can be used alone or integrated in a microflow cytometer. 【Background technique】 [0002] Space medical supervision and medical support for the health of astronauts is an important guarantee to ensure the smooth execution of manned space missions, and is directly related to whether the mission can be carried out smoothly. Due to harsh conditions such as the environment, it is very difficult to carry out on-orbit health diagnosis of astronauts. Flow cytometer is an instrument based on flow cytometry for single-cell multi-parameter analysis of cells in high-speed sample flow. and treatment evaluation provide important information. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N1/31G01N33/533
CPCG01N1/31G01N33/533
Inventor 常洪龙沙华露寻文鹏杨东
Owner NORTHWESTERN POLYTECHNICAL UNIV
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