Traditional Chinese medicine composition for animal anesthesia and preparation method of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for animal anesthesia and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following medicinal material slices in parts by weight: 5 to 30 parts of flos daturae, 4 to 13 parts of flos rhododendri, 7 to 15 parts of radix aconiti carmichaeli, 1 to8 parts of semen hyoscyami, 3 to 7 parts of venenum bufonis and 2 to 5 parts of rhizoma acori tatarinowii. The preparation method comprises the following steps: after pulverizing the six medicinal material slices through an ultrafine pulverizer, immersing the medicinal materials for 3h by utilizing warm water with the temperature of 60 DEG C, and filtering by utilizing double-layer filter paper; then boiling a concentrated solution extracted through ethanol for three times and sterilizing; centrifuging and taking supernatant; regulating the supernatant to be isotonic by utilizing 0.9 percent sodium chloride and making the volume constant; regulating the pH (Potential of Hydrogen) to 6.8 to 7.0; filtering by utilizing a micropore filter membrane and sterilizing; sterilely filling to form medicinal injection for later use. The traditional Chinese medicine composition disclosed by the invention has relatively good calming, pain easing and anesthetic actions and has an obvious inhibition effect on a central nervous system, and the effective rate reaches 66.7 percent to 93.3 percent; the traditional Chinese medicine composition has high safety performance, basically has no toxic and side effects and no residues, is suitable for clinical popularization and application, and can be industrially produced in a large scale.

Description

technical field [0001] The invention relates to the technical field of anesthetic drugs, in particular to a drug composition of a traditional Chinese veterinary drug anesthetic and a preparation method thereof. Background technique [0002] In clinical operations, anesthesia is a variety of methods used to eliminate pain, ensure the safety of sick animals, and create good surgical conditions during operations or diagnostic inspections. Surgery or inspection operations can also cause mental stress and reflex adverse reactions, such as gastrointestinal surgery can cause nausea and vomiting; prolonged uncomfortable positions can also increase the discomfort and pain of sick animals. Anesthesia allows animals to undergo surgery or diagnostic examinations in a comfortable and quiet environment without responding to adverse stimuli or temporarily losing consciousness. [0003] At present, animal anesthesia generally adopts chemical anesthesia such as non-inhalation anesthetics (S...

AI Technical Summary

Problems solved by technology

[0003] At present, animal anesthesia generally adopts chemical anesthesia such as non-inhalation anesthetics (Sutai, urethane, sodium pentobarbital, chloral hydrate, etc.) and inhalation anesthetics (ether, etc.), and its common disadvantage is the depth of anesthesia. Difficult to master, prone to accidents during anesthesia; and chemical anesthetics have certain toxic and side effects on animals

Traditional Chinese medicine has many targets and has few toxic and side effects. However, after Hua Tuo’s Mafeisan, almost no other traditional Chinese medicine anesthetics have been used in human and animal clinical trials, and Mafeisan has been completely lost.

Images