Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Phellinus igniarius traditional Chinese medicine composition as well as extraction method thereof and application thereof in preparation of anti-tumor drugs

A technology of anti-tumor drugs and compositions, applied in the directions of anti-tumor drugs, drug combinations, food ingredients containing natural extracts, etc.

Inactive Publication Date: 2017-12-29
ZHEJIANG ACAD OF TRADITIONAL CHINESE MEDICINE
View PDF9 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are few research reports on other chemical components of Phellinus, such as flavonoids and triterpenoids, but the flavonoids of Phellinus have antioxidant effects, and furanones have anti-tumor effects. It is necessary to study the non-polysaccharide components of Phellinus Phellinus for further popularization and application

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Phellinus igniarius traditional Chinese medicine composition as well as extraction method thereof and application thereof in preparation of anti-tumor drugs
  • Phellinus igniarius traditional Chinese medicine composition as well as extraction method thereof and application thereof in preparation of anti-tumor drugs
  • Phellinus igniarius traditional Chinese medicine composition as well as extraction method thereof and application thereof in preparation of anti-tumor drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] Optimum ratio of composition

[0030] The optimal ratio of Ganoderma lucidum, Phellinus japonica, and Clover is 3:1:3, and the optimal daily prescription amount is 21g.

[0031] Composition Extraction Method

[0032] Weigh the various medicinal materials in the composition in proportion, add 8 times the mass concentration of the medicinal materials in an aqueous ethanol solution with a mass concentration of 50%, soak for 0.5h, and perform ultrasonic extraction (ultrasonic intensity 100, temperature 40°C) for 0.5h; filter, ethanol extraction Liquid standby;

[0033] Add water 10 times the mass of medicinal material to the filter residue, ultrasonically extract (ultrasonic intensity 100, temperature 50°C) for 0.5h, and filter; add water 6 times the mass of medicinal material to the filter residue, ultrasonically extract for 0.5h under the same conditions, and filter; combine water extract, spare;

[0034] The alcohol extract and the water extract are respectively conce...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a phellinus igniarius traditional Chinese medicine composition as well as an extraction method thereof and application thereof in preparation of anti-tumor drugs. The phellinus igniarius traditional Chinese medicine composition is prepared from the following components by mass percent: 30-50% of ganoderma lucidum, 10-20% of phellinus igniarius and 30-50% of radix tetrastigme. The extraction method adopts ultrasonic-assisted extraction; the prepared composition extract contains the following main ingredients: polysaccharides, triterpenes, protocatechuic aldehyde, inoscavin, naringenin, 7-methoxy dihydrocamphene, phellinus igniarius flavone, dehydrovomifoliol, sakuranetin, methyl phellinus igniarius flavone, ganodenic acid, quercetin, kaempferol, and the like. The composition extract has an obvious improvement effect for cyclophosphamide-induced immune loss mice, and has a remarkable inhibiting effect for stomach cancer strains SGC7901 and BGC823, liver cancer strains HepG2 and SMMC7721, colon cancer strain HT-29, and the like. Compared with the singly used phellinus igniarius and radix tetrastigme, the composition has an obvious synergistic effect.

Description

technical field [0001] The invention relates to a Phellinus Chinese medicinal composition, its extraction method and its application in the preparation of antitumor drugs. Background technique [0002] Cancer is the second leading cause of death in humans after cardiovascular disease, posing a serious threat to human health. It is estimated that by 2030, there will be about 21 million new cancer patients worldwide, and about 13.2 million deaths. There are about 2.2 million new cancer cases and 1.6 million deaths in my country every year. Therefore, the prevention and research of malignant tumors has become a research field that global medical workers pay close attention to. [0003] Chinese medicine treatment of cancer, because of its multi-target, multi-link and multi-effect characteristics, can improve the body's immunity and play an important role in prolonging the survival period and improving the quality of life. Efficacy and unique advantages. The discovery and in-d...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61K36/48A61P35/00A23L31/00A23L33/10A23L33/105
CPCA23L31/00A23L33/10A23L33/105A23V2002/00A61K36/07A61K36/074A61K36/48A61K36/87A61K2236/331A61K2236/333A61K2236/39A61K2300/00A23V2200/308A23V2250/208A23V2250/21A23V2300/14A23V2300/48
Inventor 寿旦董宇
Owner ZHEJIANG ACAD OF TRADITIONAL CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com