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A kind of rapid hemostatic chitosan sponge pad band-aid and preparation method thereof

A technology of sponge pads and chitosan, which can be used in absorbent pads, pharmaceutical formulations, bandages, etc., and can solve the problem of single pharmacological effects

Active Publication Date: 2020-10-27
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Above-mentioned novel rapid hemostatic band-aid and medical chitosan rapid hemostatic composite dressing all can play the effect of hemostasis, but there are problems such as single pharmacological effect, and still need to further improve aspect the hemostatic effect, therefore, from giving full play to chitosan in band-aid Considering the hemostatic performance and improving the hemostatic effect, a kind of fast hemostatic chitosan sponge pad band-aid is still lacking in the prior art

Method used

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  • A kind of rapid hemostatic chitosan sponge pad band-aid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1, a kind of rapid hemostatic chitosan sponge pad Band-Aid

[0037] The fast hemostatic chitosan sponge pad band-aid is made up of medical release paper, sponge pad and viscose cloth, the sponge pad is located in the middle of the viscose cloth, and the release paper is attached to the viscose cloth and the sponge pad. The sponge cushion layer contains a rapid hemostatic agent, and the rapid hemostatic agent is composed of the following components and their mass parts: 35 parts of chitosan mixture, 10 parts of glucose aqueous solution with a mass concentration of 45% and 5 parts of mannose.

[0038] The chitosan mixture is composed of chitosan with a deacetylation degree of 80%, chitosan quaternary ammonium salt and hydroxypropyl chitosan in a mass ratio of 5:3:1.

[0039] Preparation:

[0040] S1: Take the chitosan mixture, aqueous glucose solution and mannose according to the specified mass parts, place them in the reactor, and add an aqueous acetic acid s...

Embodiment 2

[0046] Embodiment 2, a kind of rapid hemostasis chitosan sponge pad Band-Aid

[0047] The fast hemostatic chitosan sponge pad band-aid is made up of medical release paper, sponge pad and viscose cloth, the sponge pad is located in the middle of the viscose cloth, and the release paper is attached to the viscose cloth and the sponge pad. The sponge cushion layer contains rapid hemostatic agent, which consists of the following components and their mass parts: 55 parts of chitosan mixture, 15 parts of glucose aqueous solution with a mass concentration of 55% and 8 parts of mannose.

[0048] The chitosan mixture is composed of chitosan with a deacetylation degree of 90%, chitosan quaternary ammonium salt and hydroxypropyl chitosan in a mass ratio of 8:2:1.

[0049] Preparation:

[0050] S1: Take the chitosan mixture, glucose aqueous solution and mannose according to the specified mass parts, place them in the reactor, add the acetic acid aqueous solution with a volume concentrati...

Embodiment 3

[0056] Embodiment 3, a kind of rapid hemostasis chitosan sponge pad Band-Aid

[0057] The fast hemostatic chitosan sponge pad band-aid is made up of medical release paper, sponge pad and viscose cloth, the sponge pad is located in the middle of the viscose cloth, and the release paper is attached to the viscose cloth and the sponge pad. The sponge cushion layer contains a rapid hemostatic agent, which consists of the following components and their mass parts: 48 parts of chitosan mixture, 12 parts of glucose aqueous solution with a mass concentration of 50% and 7 parts of mannose.

[0058] The chitosan mixture is composed of chitosan with a deacetylation degree of 85%, chitosan quaternary ammonium salt and hydroxypropyl chitosan in a mass ratio of 7:2.5:1.

[0059] Preparation:

[0060] S1: Take the chitosan mixture, glucose aqueous solution and mannose according to the specified mass parts, place them in the reactor, add the acetic acid aqueous solution with a volume concent...

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Abstract

The invention belongs to the technical field of medical instruments and particularly relates to a chitosan sponge mat adhesive bandage capable of rapidly stopping bleeding and a preparation method of the chitosan sponge mat adhesive bandage. The chitosan sponge mat adhesive bandage comprises medical isolation paper, a sponge mat layer and adhesive cloth, wherein the sponge mat layer is located in the middle section of the adhesive cloth, the adhesive cloth and the sponge mat layer are adhered with the isolation paper, and the sponge mat layer contains a rapid bleed-stopping medicament; and the rapid bleed-stopping medicament contains the following components in parts by mass: 35-55 parts of a chitosan mixture, 10-15 parts of a glucose water solution and 5-8 parts of mannose. The chitosan sponge mat adhesive bandage provided by the invention is capable of rapidly and effectively stopping bleeding, has the effects of resisting bacteria, easing and relieving pain, promoting wound healing and the like, has no toxicity and irritation and is high in use safety and applicable to the medical rapid bleed stopping, the promotion of wound healing and the like.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a rapid hemostasis chitosan sponge pad band-aid and a preparation method thereof. Background technique [0002] Band-aid, also known as "hemostatic plaster", is the most commonly used surgical drug in people's lives. It is usually used for emergency treatment of small trauma, so as to temporarily stop bleeding and protect the wound surface. The hemostatic materials currently used for Band-Aids mainly include zeolite, collagen powder, potato starch, gelatin sponge, collagen sponge, oxidized regenerated cellulose, and fibrin glue, etc., each of which has certain shortcomings, such as tissue adhesion of gelatin and collagen The hemostatic function of both depends on sufficient platelets and coagulation factors; oxidized regenerated cellulose and fibrin glue may cause infection; porous zeolite and potato starch release a lot of heat after absorbing water in the bl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61L15/20A61L15/42A61L15/44A61L15/46A61F13/02
CPCA61F13/00063A61F13/0266A61F13/0289A61F2013/00089A61L15/20A61L15/28A61L15/425A61L15/44A61L15/46A61L2300/232A61L2300/402A61L2300/404A61L2400/04C08L5/08
Inventor 车七石
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
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