A mouse heart imaging system and method based on prospective ECG gating

Abstract

The invention belongs to the technical field of image processing and discloses a mouse cardiac imaging system and method based on prospective ECG (electrocardiogram) gating. The system comprises: an ECG signal acquisition front end for acquiring mouse real-time heartbeat information during CT (computed tomography) image acquisition; a control board that acquires mouse ECG information to generate a triggering level and trigger an X-ray detector so as to finish mouse projection image acquisition; a Micro-CT acquisition system for reconstructing 360 pieces of projection data. Motion phase of mouse heart is judged by capturing ECG information of a live mouse and extracting R-wave peaks of the mouse ECG signals; the X-ray detector is triggered by the R-wave peaks to perform projection data sequence acquisition on the mouse heart via the Micro-CT imaging technology, multiple phase images of the mouse at each angle within the whole cardiac motion period are acquired, and the reconstructed multiple phase images of the mouse heart within the whole heartbeat period are restored.

Description

technical field [0001] The invention belongs to the technical field of image processing, and in particular relates to a mouse heart imaging system and method based on prospective ECG gating. Background technique [0002] As a medical imaging system for small animals, Micro-CT has the characteristics of high imaging resolution compared with traditional medical CT. The spatial resolution can reach the micron level, and its reconstruction accuracy is also higher than that of traditional medical CT. Micro-CT imaging is of great significance to cardiac imaging, but there are some problems in traditional Micro-CT imaging: due to the use of gating technology for time-sharing extraction of projection data, traditional dynamic Micro-CT systems have only The problem of being able to acquire an image, which leads to too slow acquisition speed, greatly increases the exposure of X-rays and reduces the efficiency; the shortening of acquisition time means that the exposure time is reduced,...

AI Technical Summary

Problems solved by technology

[0003] To sum up, the problems existing in the existing technology are: traditional Micro-CT imaging has too slow acquisition speed, which greatly increases the exposure of X-rays and reduces the efficiency; the contrast of the image is low, which reduces the confidence of the reconstruction result. noise ratio

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