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Preparation method of eye nursing composition liposome

A technology for eye care and composition, which is applied in the field of preparation of eye care composition liposomes, can solve the problems of high irritation of vitamin A alcohol, no crow's feet at the corners of the eyes, water retention, etc., and achieve good stability and encapsulation High efficiency and excellent effect

Active Publication Date: 2017-10-20
PROYA COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, vitamin A alcohol is very irritating and can easily cause eye skin allergies; peptides have the problem that the molecular weight is too large and difficult to be absorbed by the skin
For dark circles, whitening agents are generally used to reduce pigmentation, or adding caffeine to accelerate blood circulation, but the main cause of dark circles is poor capillary blood flow, traditional whitening agents cannot solve the problem, and caffeine ranks first in my country Psychotropic drugs, the state implements special management on them, and the procurement and use are restricted
In addition, there are still few skin care products on the market for removing eye bags. A few big brands use the method of promoting blood circulation to decompose fat and soothing the skin to reduce eye bags, because eye bags are mainly caused by water retention, and improper treatment methods lead to actual results. little
[0004] Although there are many kinds of eye care products on the market, there are almost no products that can effectively solve crow's feet, dark circles and bags under the eyes at the same time, and it is difficult to meet the simple and fast use needs of consumers under the pressure of modern life
In addition, most products lack an understanding of the formation mechanism of eye skin problems when designing, and cannot fundamentally solve the problem

Method used

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  • Preparation method of eye nursing composition liposome
  • Preparation method of eye nursing composition liposome
  • Preparation method of eye nursing composition liposome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment example 1

[0050] A preparation method of eye care composition liposome, comprising the following steps:

[0051] 1) Weigh carnosine, fructose diphosphate sodium salt, tranexamic acid, and acetyl hydroxyproline according to a mass ratio of 5:5:6:4, and mix to obtain an eye care composition;

[0052] 2) Weigh the above-mentioned eye care composition and ethanol according to a mass ratio of 1:10, mix and heat the two to 70°C, stir with an IKA stirrer at 500 rpm until completely dissolved, and obtain an eye care composition dispersion;

[0053] 3) Weigh cetearyl glucoside (TEGO CARE CG90, Evonik, Germany), potassium cetyl phosphate (AMPHISOL K, DSM, Netherlands) according to the mass ratio of 5: 1: 30, deionized water, three After mixing, heat to 80°C, and stir at a low speed of 500 rpm with an IKA stirrer until completely dissolved to obtain a surfactant composition solution;

[0054] 4) Weigh 25% of the eye care composition dispersion obtained in step 2, 10% of the surfactant composition...

Embodiment example 2

[0057] A preparation method of eye care composition liposome, comprising the following steps:

[0058] 1) Weigh carnosine, fructose diphosphate sodium salt, tranexamic acid, and acetyl hydroxyproline according to a mass ratio of 5:5:6:4, and mix to obtain an eye care composition;

[0059] 2) Weigh the above-mentioned eye care composition, propylene glycol and glycerin mixture (propylene glycol: glycerol is 1:1) according to the mass ratio of 1:10, mix and heat the three to 80°C, stir with an IKA stirrer at 500rpm until completely dissolved, and obtain eye care composition dispersion;

[0060] 3) Weigh cetearyl glucoside (TEGO CARE CG90, Evonik, Germany), potassium cetyl phosphate (AMPHISOL K, DSM, Netherlands) according to the mass ratio of 5: 1: 30, deionized water, three After mixing, heat to 80°C, and stir at a low speed of 500 rpm with an IKA stirrer until completely dissolved to obtain a surfactant composition solution;

[0061] 4) Weigh 25% of the eye care composition ...

Embodiment example 3

[0064] A preparation method of eye care composition liposome, comprising the following steps:

[0065] 1) Weigh carnosine, fructose diphosphate sodium salt, tranexamic acid, and acetyl hydroxyproline according to a mass ratio of 5:5:6:4, and mix to obtain an eye care composition;

[0066] 2) Weigh the above-mentioned eye care composition and butanediol according to a mass ratio of 1:10, mix and heat the two to 75°C, stir with an IKA stirrer at 500rpm until completely dissolved, and obtain an eye care composition dispersion;

[0067] 3) Weigh cetearyl glucoside (TEGO CARE CG90, Evonik, Germany), potassium cetyl phosphate (AMPHISOL K, DSM, Netherlands) according to the mass ratio of 5: 1: 30, deionized water, three After mixing, heat to 75°C, and stir with an IKA stirrer at a low speed of 500 rpm until completely dissolved to obtain a surfactant composition solution;

[0068] 4) Weigh 25% of the eye care composition dispersion obtained in step 2, 10% of the surfactant compositi...

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Abstract

The invention relates to a preparation method of eye nursing composition liposome. The preparation method is characterized by comprising the following steps: A, mixing carnosine, fructose diphosphate sodium, tranexamic acid and acetyl hydroxyproline according to a mass ratio of 5 to 5 to 6 to 4 to obtain an eye nursing composition; B mixing the eye nursing composition and water-soluble alcohol according to a mass ratio of 1 to 10, and heating a mixture to 70-80 DEG C; C, mixing cetearyl glucoside, potassium cetyl phosphate and deionized water according to a mass ratio of 5 to 1 to 30 to obtain a surfactant composition solution; D, mixing 25 percent of an eye nursing composition dispersion liquid, 10 percent of the surfactant composition solution, 5-10 percent of hydrogenated lecithin and the balance of deionized water, and heating a mixture to 70-80 DEG C to obtain a premixed solution; and E, carrying out high pressure homogenization on the premixed solution for 1-3 times by using a high pressure homogenizer at the pressure of 1000bar and the temperature of 70-75 DEG C, and cooling a product to room temperature to obtain the eye nursing composition liposome. The eye nursing composition liposome has the beneficial effects of removing fishtail lines, dark eye circles and eye haustra.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a preparation method of eye care composition liposome. Background technique [0002] The total thickness of the eye epidermis and dermis is about 0.55 mm, which is only a quarter of the facial skin and is the thinnest part of the human skin. There are almost no sebaceous glands and sweat glands under the eye skin, less sebum content, lack of elastic fibers and collagen structure, easy to lose elasticity and lead to aging. At the same time, the nerve fibers and capillaries around the eyes are densely distributed and are very sensitive. These characteristics make the eye skin appear dull and loose under the influence of the external environment and bad living habits, thus causing problems such as crow's feet, dark circles, and bags under the eyes. [0003] Eye skin is the most fragile but most active part of the human body, and its care has become one of the focuses in the fiel...

Claims

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Application Information

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IPC IPC(8): A61K8/64A61K8/14A61K8/44A61K8/49A61K8/55A61K8/60A61Q19/00
CPCA61K8/14A61K8/44A61K8/4913A61K8/553A61K8/60A61K8/602A61K8/64A61K2800/412A61K2800/413A61K2800/56A61K2800/596A61Q19/005
Inventor 晏青陈玉燕金激王虹霞吕旭阳焦夏青蒋丽刚
Owner PROYA COSMETICS
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