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General tumor vaccine composition, spray and preparation method thereof

A technology of tumor vaccines and compositions, which is applied in the field of anti-tumor vaccines, and can solve problems such as the failure to widely carry out education on tumor prevention and health care

Inactive Publication Date: 2017-06-20
美国安泰健康投资管理公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] On the one hand, the occurrence of tumors is closely related to environmental pollution and living habits. On the other hand, my country’s cancer prevention and treatment has always been a problem of emphasizing treatment and ignoring prevention. Tumor prevention and health care education has not been widely carried out, or it only exists at the stage of shouting slogans. no actual action

Method used

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  • General tumor vaccine composition, spray and preparation method thereof
  • General tumor vaccine composition, spray and preparation method thereof
  • General tumor vaccine composition, spray and preparation method thereof

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Embodiment Construction

[0028] The principles and features of the present invention are described below in conjunction with examples, which are only used to explain the present invention and are not intended to limit the scope of the present invention.

[0029] 1. Screening of those with anti-tumor ability

[0030] Those with anti-tumor ability were screened from the healthy population. The screening scheme was shown in Table 1, and people with a first-level (score > 85 points) were selected as peripheral blood donors.

[0031] Table 1 Screening of those with anti-tumor ability

[0032]

[0033]

[0034]

[0035] 2. Preparation of Universal Tumor Vaccine Composition

[0036] Prepare a general tumor vaccine composition by the following method

[0037] 1) Volunteers were selected from the group with great anti-tumor ability, and 100ml of peripheral blood containing PBMC was collected with a blood cell apheresis machine;

[0038] 2) Centrifuge the above-mentioned peripheral blood containing ...

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Abstract

The invention relates to a method for preparing a general tumor vaccine composition. The method comprises the following steps of screening a person with anti-tumor ability from healthy groups according to the anti-tumor ability index; collecting peripheral blood from the person with the anti-tumor ability; performing separation from the peripheral blood to obtain mononuclear cells and plasma; extracting protein in the plasma to obtain a first protein coarse extract I; culturing the mononuclear cells into one kind or several kinds of immune cell culture materials; extracting a protein coarse extract II from the immune cell culture materials; uniformly mixing the protein coarse extract I and the protein coarse extract II; performing freeze drying; obtaining the powder which is the general tumor vaccine. The invention also provides a general tumor vaccine composition prepared by the method and an automation spray. The general tumor vaccine composition and the automation spray contain various kinds of anti-tumor factors; good prevention and health care effects can be achieved on tumor susceptible people groups.

Description

technical field [0001] The invention relates to the field of anti-tumor vaccines, and more particularly relates to a general tumor vaccine composition and spray and a preparation method thereof. Background technique [0002] Cancer is a serious threat to human health and life. According to the data released by the International Agency for Research on Cancer, about 8 million people worldwide die of cancer every year. Analysis of detection data reveals that there are regional and familial phenomena in the occurrence of cancer. For example, from 2003 to 2007, the 32 national cancer registries were mainly distributed in coastal areas, including 7 high-incidence sites of cancer, namely Qidong in Jiangsu, Jiashan in Zhejiang, Changle in Fujian, Linzhou in Henan, Yanting in Sichuan, Fusui in Guangxi, Linqu in Shandong, etc. . Cancer family refers to a family with a high incidence of malignant tumors (about 20%), an earlier age of onset, usually inherited in an autosomal dominant ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/16A61K35/17A61K35/15A61K9/12A61P35/00
CPCA61K9/12A61K35/15A61K35/16A61K35/17A61K2300/00
Inventor 闫小君罗进
Owner 美国安泰健康投资管理公司
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