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Preparation method of microcrystalline cellulose

A technology of microcrystalline cellulose and pulp, which is applied in the direction of pulping with inorganic alkali, can solve the problems of many impurities, improvement of product quality, unfavorable microcrystalline cellulose, etc., and achieve the effect of increasing raw material sources and improving quality

Active Publication Date: 2017-05-31
江苏宣泰药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The above-mentioned inventions all use biomass raw materials, which have complex components and many impurities, which are not conducive to the improvement of the quality of microcrystalline cellulose products.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0024] A preparation method of microcrystalline cellulose, comprising the following steps:

[0025] Pretreatment of chemical pulp sheet: disperse the pulp sheet in water, configure it into a pulp suspension with a mass fraction of 0.1%-15%, soak it for 12-72h to make it swell, and then react it in the reactor to obtain slurry;

[0026] Wherein, the commercial chemical pulp board is at least one of coniferous wood pulp board, hardwood pulp board and bamboo pulp board.

[0027] Further, the α-cellulose content of the commercial chemical pulp board is 60%-90%, and the average degree of polymerization is 700-1400.

[0028] Further, in the pretreatment step of the chemical pulp board, the temperature of the reactor is 160°C-200°C, and the reaction time in the reactor is 2-60min.

[0029] Alkali treatment of slurry: Separating the solid and liquid of the slurry obtained after pretreatment, washing the obtained solid slurry with water to neutrality and then treating it with lye; in ...

Embodiment 1

[0037] (1) Disperse the commercial bamboo pulp board in water, configure it into a 0.1% pulp suspension, and soak it for 24 hours to make it fully swell. Place the prepared pulp suspension in a high-temperature reaction kettle and treat it at 180°C for 15 minutes to make it fully react.

[0038] (2) Separating the treated slurry from solid to liquid, and washing the obtained solid slurry with clear water to neutrality, the mass fraction of the washed slurry is 5% potassium hydroxide solution at 60°C and 10% slurry The concentration was treated for 5 minutes.

[0039] (3) The alkali-treated slurry is washed with clear water to neutrality, and then treated with 3mol / L hydrochloric acid: sulfuric acid molar ratio 1:1 mixed acid solution at 65°C for 30 minutes to fully hydrolyze it to obtain Blend containing microcrystalline cellulose.

[0040] (4) The mixture was separated from solid and liquid, washed with water until neutral, and dried in a vacuum oven at 0.08 MPa and 70° C. ...

Embodiment 2

[0043] (1) Disperse the commercial coniferous wood pulp plate in water, configure it into a 1% pulp suspension, and soak it for 36 hours to make it fully swell. Put the configured pulp suspension in a high-temperature reaction kettle, and treat it at 190°C for 30 minutes to make it fully react.

[0044] (2) Separating the treated slurry from solid to liquid, and washing the obtained solid slurry with clear water to neutrality, the mass fraction of the washed slurry is 15% sodium hydroxide solution at 50°C and 20% slurry The concentration was treated for 50 minutes.

[0045] (3) The alkali-treated slurry was washed with water to neutrality, and then treated with 1 mol / L sulfuric acid at 75° C. for 20 minutes to fully hydrolyze it, thereby obtaining a mixture containing microcrystalline cellulose.

[0046] (4) The mixture was separated into solid and liquid, washed with water until neutral, and dried in a vacuum oven at 0.085 MPa and 60° C. for 6 hours. Thereafter, the obtaine...

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Abstract

The invention discloses a preparation method of microcrystalline cellulose. The preparation method is characterized by comprising the following steps: (1) preprocessing a chemical pulp board: dispersing a chemical pulp board in water to prepare a paper pulp turbid liquid (0.1-15%), soaking the pulp board for 12 to 72 hours to swell the pulp board, and delivering the pulp board into a reactor to carry out reactions to obtain slurry; (2) carrying out an alkali treatment on the slurry: after the pretreatment, subjecting the obtained slurry to solid-liquid separation, washing the solid slurry by clean water until the solid slurry becomes neutral, and processing the solid slurry by alkali liquor; (3) carrying out an acid treatment on the slurry: after the alkali treatment, washing the slurry by clean water until the slurry becomes neutral, then adding diluted acid (0.5-5 mol / L), and carrying out hydrolysis at a temperature of 65 to 95 DEG C to obtain a mixture containing microcrystalline cellulose; and (4) obtaining microcrystalline cellulose: subjecting the mixture to solid-liquid separation, washing the solids by clean water until the solid becomes neutral, and drying the solids in vacuum to obtain the microcrystalline cellulose.

Description

technical field [0001] The invention belongs to the technical fields of applied chemistry and pulping and papermaking engineering, and further relates to a preparation method of microcrystalline cellulose. Background technique [0002] Microcrystalline cellulose is a free-flowing extremely fine short rod-shaped or powder-like porous particle that is hydrolyzed to the limit degree of polymerization of natural cellulose. It is a high-value functional cellulose and is widely used in the pharmaceutical industry and food industry. , chemical industry, daily chemical industry, synthetic leather industry, food, light industry and other fields. As a natural polymer compound with rich resources and wide application, microcrystalline cellulose has great research space, broad development and market prospects. In existing studies, the main preparation principles and methods of microcrystalline cellulose are generally the same, that is, the processes of cellulose purification, acid hydr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B15/02D21C3/02
CPCC08B15/02D21C3/02
Inventor 岳小鹏徐洋徐永建
Owner 江苏宣泰药业有限公司
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