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Natural cosmetic anti-corrosion composition with strong-effect broad-spectrum antibacterial activity

A natural antiseptic and composition technology, applied in the directions of medical preparations, cosmetics, cosmetic preparations containing active ingredients, etc., can solve the problems of poor bacteriostatic activity, etc., and achieve high-efficiency bacteriostatic effect and wide bacteriostatic spectrum.

Inactive Publication Date: 2017-05-31
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to replace or reduce the consumption of chemical preservatives, and to overcome the defect of poor antibacterial activity of a single plant antibacterial extract, to provide a kind of antiseptic composition containing several plant extracts. The synergistic effect between them greatly improves the antibacterial effect and antibacterial spectrum of the antiseptic composition

Method used

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  • Natural cosmetic anti-corrosion composition with strong-effect broad-spectrum antibacterial activity
  • Natural cosmetic anti-corrosion composition with strong-effect broad-spectrum antibacterial activity
  • Natural cosmetic anti-corrosion composition with strong-effect broad-spectrum antibacterial activity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1 natural antiseptic composition

[0018]

[0019]

Embodiment 2

[0020] Example 2 Bacteriostatic effect evaluation of natural antiseptic composition

[0021] 1. Preparation of Sample Solution

[0022] Weigh the same amount of Magnolia officinalis extract, Phyllostachys pubescens extract, Speranthema osmanthus extract and cinnamon extract respectively, make 200mg / mL sample solution with ethanol aqueous solution, combine according to the proportion in Example 1, set aside .

[0023] 2. Preparation of bacterial suspension

[0024] 1) Test strains: Staphylococcus aureus (ATCC6538), Escherichia coli (ATCC11229), Candida albicans (ATCC10231), Aspergillus niger (ATCC16404).

[0025] 2) Medium:

[0026] Beef extract-peptone medium (for bacteria): 3g beef extract, 10g tryptone, 5g sodium chloride, add water to 1000mL, adjust pH to 7.2-7.4, autoclave (103.4kPa, 121°C, 20min), set aside . Add 20g of agar when preparing solid medium.

[0027] Wort medium (for yeast): Dilute the raw material of fermented beer (without adding hops) to 10 Berlin, hi...

Embodiment 3

[0038] The minimum inhibitory concentration (MIC) of embodiment 3 natural preservative composition and the mensuration of minimum bactericidal concentration (MBC)

[0039] 1. Minimum Inhibitory Concentration (MIC)

[0040] The minimum inhibitory concentration was determined by the constant broth dilution method. The plant extract was dissolved in dimethyl sulfoxide (DMSO) to 1000 mg / mL as the stock solution, and then serially diluted to a series of concentrations. Take several sterilized test tubes, add 1.8mL liquid culture medium to each test tube, 0.1mL1×10 7 CFU / mL bacterial suspension (spore suspension) and 0.1mL plant extract. Bacteria were incubated in a constant temperature water bath shaker (200r / min) at 37°C for 24 hours, yeast and mold were incubated in a water bath shaker at 28°C for 48 hours, and then observed whether there was bacterial growth in each test tube to inhibit the growth of bacteria The lowest concentration was taken as the MIC. Each sample was rep...

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Abstract

The invention discloses a natural plant extraction composition for cosmetic anti-corrosion. The composition is prepared by compounding 2 to 8 kinds of antibacterial and antifungal plant extracts, and the weight percentage of each kind of extract is 10 to 80 percent. The prepared natural anti-corrosion composition has the advantages that through the matching of plant extracts with antibacterial and antifungal effects, the effects of simultaneously damaging positions of bacterium and fungus cytomembranes, cell walls, nucleic acid, zymoprotein and the like are achieved; the antibacterial capability of the natural plant extraction composition is enhanced, so that the strong-effect and broad-spectrum antibacterial effects can be achieved. The natural anti-corrosion composition is obtained through compounding plant extracts; the antibacterial effect is high; the antibacterial spectrum is broad; the composition can be used as a preservative to be safely and efficiently applied to the fields of cosmetics and the like.

Description

technical field [0001] The invention belongs to the technical field of natural antiseptic cosmetics, and in particular relates to the preparation and compounding of a natural antiseptic composition with strong and broad-spectrum antibacterial activity. Background technique [0002] Cosmetics are easily polluted by microorganisms and deteriorate during production, storage and use, and with the increase in functional diversification of cosmetics, the addition of nutrients will make it easy for microorganisms to grow and reproduce in the product, while the addition of preservatives will inhibit The growth of these microorganisms prevents the spoilage of products and reduces the harm to the skin caused by product deterioration. At this level, preservatives are essential ingredients in cosmetics. [0003] However, in recent years, with people’s awareness of the safety of preservatives and the “disgust” of synthetic preservatives, after long-term research, it has been found that c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/9789A61Q19/00A61Q19/08A61Q17/04A61Q19/02
CPCA61K8/97A61K2800/524A61K2800/5922A61Q17/04A61Q19/00A61Q19/02A61Q19/08
Inventor 梁蓉曹光群杨成张美龄
Owner JIANGNAN UNIV
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